vectorial synthesis
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Vectorial synthesis is synthesis of exported
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
s by
ribosome Ribosomes () are molecular machine, macromolecular machines, found within all cell (biology), cells, that perform Translation (biology), biological protein synthesis (messenger RNA translation). Ribosomes link amino acids together in the order s ...
s in which the
ribosome-nascent chain complex Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polypeptide may be stalled by one of several method ...
is bound directly to the
endoplasmic reticulum The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryote, eukaryotic cell, and has many other important functions such as protein folding. The word endoplasmic means "within the cytoplasm", and reticulum is Latin for ...
(ER) and the nascent peptide chain moves through the ER membrane as it emerges from the ribosome.


References


Further reading

Fuller-Pace, F., Peters, G., Dickson, C
''Cell transformation by kFGF requires secretion but not glycosylation''
Journal of Cell Biology (1991) 115 (2), pp. 547–555 Protein folding Protein biosynthesis {{Protein-stub