Biological
cell
Cell most often refers to:
* Cell (biology), the functional basic unit of life
Cell may also refer to:
Locations
* Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery w ...
s which form
bonds with a substrate and are at the same time subject to a flow can form long thin membrane cylinders called tethers, which connect the adherent area to the main body of the cell. Under physiological conditions,
neutrophil
Neutrophils (also known as neutrocytes or heterophils) are the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form an essential part of the innate immune system, with their functions varying in ...
tethers can extend to several micrometers.
In biochemistry, a tether is a molecule that carries one or two carbon intermediates from one active site to another. They are commonly used in lipid synthesis, gluconeogenesis, conversion of pyruvate into Acetyl CoA via PDH complex. Common tethers are lipoate -lysine residue complex associated with dihydrolipoyl transacetylase, which is used for carrying hydroxyethyl from hydroxyethyl TPP. This compound forms Acetyl- CoA, a convergent molecule in metabolic pathways.
Another tether is biotin- lysine residue complex associated with pyruvate carboxylase, an enzyme which plays an important role in gluconeogenesis. It is involved in the production of oxaloacetate from pyruvate.
One of the biological tethers used in the synthesis of fats is a β- mercaptoethylamine-pantothenate complex associated with an acyl carrier protein.
{{DEFAULTSORT:Tether (Cell Biology)
Biochemistry
Cell biology