A sweat allergy is the exacerbation of
atopic dermatitis associated with an
elevated body temperature and resulting increases in the production of
sweat. It appears as small reddish
welts that become visible in response to increased temperature and resulting production of sweat. It can affect all ages. Sweating can trigger intense itching or
cholinergic urticaria. The protein MGL_1304 secreted by
mycobiota (fungi) present on the skin such as ''
Malassezia globosa'' acts as a
histamine
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Since histamine was discover ...
or
antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune respon ...
. People can be
desensitized using their own samples of sweat that have been purified that contains small amounts of the allergen.
The allergy is not due to the sweat itself but instead to an allergy-producing protein secreted by bacteria found on the skin.
(CU) is one of the
physical urticaria (hives) which is provoked during sweating events such as exercise, bathing, staying in a heated environment, or emotional stress. The hives produced are typically smaller than classic hives and are generally shorter-lasting.
Multiple subtypes have been elucidated, each of which require distinct treatment.
has been found to suppress the allergic response, along with showering.
See also
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Miliaria
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Exercise-induced anaphylaxis
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Idiopathic pure sudomotor failure
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Hypohidrosis
Hypohidrosis is a disorder in which a person exhibits diminished sweating in response to appropriate stimuli. In contrast with hyp''er''hidrosis, which is a socially troubling yet often benign condition, the consequences of untreated hypohidros ...
*
Fabry disease
Fabry disease, also known as Anderson–Fabry disease, is a rare genetic disease that can affect many parts of the body, including the kidneys, heart, and skin. Fabry disease is one of a group of conditions known as lysosomal storage diseases. ...
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Allergy
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derm ...
*
Food allergy
*
List of allergens
*
Tree nut allergy
*
Cholinergic urticaria
References
Allergology
Dermatitis
Immunology
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