_highlighting_the_sustentacular_cells_in_a_[[paraganglioma._[[S100_protein.html" style="text-decoration: none;"class="mw-redirect" title="paraganglioma.html" style="text-decoration: none;"class="mw-redirect" title="Micrograph highlighting the sustentacular cells in a [[paraganglioma">Micrograph highlighting the sustentacular cells in a [[paraganglioma. [[S100 protein">S100 [[immunostain
A sustentacular cell is a type of cell primarily associated with structural support, they can be found in various tissues.
* Sustentacular cells of the olfactory epithelium
(also called supporting cells) have been shown to be involved in the phagocytosis of dead neurons, odorant transformation and xenobiotic metabolism.
* One type of sustentacular cell is the Sertoli cell
, in the testicle
. It is located in the walls of the seminiferous tubules
and supplies nutrients to sperm. They are responsible for the differentiation of spermatids, the maintenance of the blood-testis barrier
, and the secretion of inhibin
, androgen-binding protein
and Mullerian-inhibiting factor
* The organ of Corti
in the inner ear
and taste bud
s also contain sustentacular cells.
* Another type of sustentacular cell is found with glomus cell
s of the carotid
and aortic bodies
* About 40% of carcinoid
s have a scattering of sustentacular cells, which stain positive for S-100