Pyronaridine is an
antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s.
In a small (n=88) malaria study in Camaroon, pyronaridine had a 100% cure rate, compared with 60% for
chloroquine.
It is one of the components of the
artemisinin combination therapy
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young c ...
pyronaridine/artesunate
Artesunate/pyronaridine, sold under the brand name Pyramax, is a fixed-dose combination medication for the treatment of malaria. It can be used for malaria of both the '' P. falciparum'' and '' P. vivax'' types. It combines artesunate and pyronar ...
(Pyramax).
It has also been studied as a potential anticancer drug, and treatment for Ebola. The combination of pyronaridine and artesunate has been evaluated to have a synergistic effect of stronger antiviral effect and less toxicity. The combination of pyronaridine and artesunate is being studied as a possible treatment for moderate to severe SARS-COV-2.
References
Antimalarial agents
Chinese discoveries
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