phosphopantothenoylcysteine decarboxylase
   HOME

TheInfoList



OR:

The enzyme phosphopantothenoylcysteine decarboxylase ()
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the chemical reaction :N- R)-4'-phosphopantothenoylL-cysteine \rightleftharpoons pantotheine 4'-phosphate + CO2 This enzyme belongs to the family of
lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, to be specific the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is N- R)-4'-phosphopantothenoylL-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming). This enzyme participates in
coenzyme A Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a subs ...
(CoA) biosynthesis from pantothenic acid.


Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and .


References

* * EC 4.1.1 Enzymes of known structure {{4.1-enzyme-stub