HOME

TheInfoList



OR:

Pendimethalin is an
herbicide Herbicides (, ), also commonly known as weedkillers, are substances used to control undesired plants, also known as weeds.EPA. February 201Pesticides Industry. Sales and Usage 2006 and 2007: Market Estimates. Summary in press releasMain page f ...
of the dinitroaniline class p.328 used in premergence and postemergence applications to control annual grasses and certain
broadleaf weeds Broadleaf weeds are unwanted tough plants that may grow in lawns, gardens or yards. They can be easy to spot when growing among grasses. They multiply with ease and can be very hard to eradicate. Basic characteristics Broadleaf weeds can emerge ...
. It inhibits cell division and cell elongation. Pendimethalin is listed in the K1-group according to the Herbicide Resistance Action Committee (HRAC) classification and is approved in Europe, North America, South America, Africa, Asia and Oceania for different crops including cereals (wheat, barley, rye, triticale), corn, soybeans, rice, potato, legumes, fruits, vegetables, nuts as well as lawns and ornamental plants.


Use

Pendimethalin protects crops like wheat, corn, soybeans, potatoes, cabbage, peas, carrots, and asparagus. It is used to control annual grasses and certain broadleaf weeds which interfere with growth, development, yield and quality of agricultural and horticultural crops by competing on nutrients, water and light. In areas where weed infestation is particularly high, yield losses can render wheat production economically unviable. In addition to wheat, a large number of crops are grown in Europe that are a relatively small percentage of total agricultural output. Herbicide options are limited for these minor crops, with few effective herbicides available in the vegetable sector. Long-term field studies performed in Germany by governmental research and advisory institutes together with farmers rank Pendimethalin as an efficient herbicide to control blackgrass, regarding to weed control efficacy, crop yield, treatment costs and environmental impact.


Mode of action

Pendimethalin acts both pre-emergence, that is before weed seedlings have emerged, and early post-emergence. Pendimethalin inhibits root and shoot growth. It controls the weed population and prevents weeds from emerging, particularly during the crucial development phase of the crop. Its primary
mode of action A mode of action (MoA) describes a functional or anatomical change, resulting from the exposure of a living organism to a substance. In comparison, a mechanism of action (MOA) describes such changes at the molecular level. A mode of action is impo ...
is to prevent plant cell division and elongation in susceptible species. In the HRAC classification of herbicides according their mode of action, pendimethalin is listed in group K1.


Risk factor for developing pancreatic cancer

In a controversial study, published in the ''International Journal of Cancer'', it has been suggested that Pendimethalin exposure is associated with higher incidence of
pancreatic cancer Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the ability to invade other parts of the body. A number of types of pancr ...
. No compelling data exists that it causes pancreatic or any other cancer. It remains in good standing with the regulatory agencies in virtually all world markets, again where it is enormously economically important and would cost large amounts of resources to stop being used.


Resistance

Herbicide resistance typically increases production costs and limits options for herbicide selection, cultivations and rotations. Up to 2009 Pendimethalin did not show resistance. It is not cross-resistant with other grass weed herbicides. This means that Pendimethalin supports the effects of other supplementary grass weed herbicides that use a different mode of action.Moss, S. R. and R. Hull: '' The value of pre-emergence herbicides for combating herbicide-resistant Alopecurus myosuroides (blackgrass).'' In: '' Aspects of Applied Biology.'' Nr. 91, 2009. ''
Lolium rigidum ''Lolium rigidum'' is a species of annual grass. Common names by which it is known include annual ryegrass, a name also given to Italian ryegrass (''Lolium multiflorum''), rigid ryegrass, stiff darnel, Swiss ryegrass and Wimmera ryegrass. It is ...
'' has evolved resistance to pendimethalin, at least in part due to increased
cytochrome P450 Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various co ...
activity.


Registrative status

Pendimethalin is registered globally for a wide range of crops, according to human and environmental safety standards by the European Commission, US-EPA, Canada-PMRA, Japan, Brazil-ANVISA and others.


Tradenames

Tradenames include Satellite, Halts, Prowl, PRE-M, Stomp, Stealth and Pendulum, Hilpendi etc.


References


External links

* {{Herbicides Anilines Nitrobenzenes Endocrine disruptors Preemergent herbicides Alkyl-substituted benzenes Secondary amines