anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having it ...

, the orbit is the cavity or socket of the

skull The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, th ...

in which the

eye Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and conv ...

and its appendages are situated. "Orbit" can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is , of which the eye occupies . The orbital contents comprise the eye, the orbital and retrobulbar fascia,

extraocular muscles The extraocular muscles (extrinsic ocular muscles), are the seven extrinsic muscles of the human eye. Six of the extraocular muscles, the four recti muscles, and the superior and inferior oblique muscles, control movement of the eye and the ...

cranial nerve Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and f ...

s II, III, IV, V, and VI, blood vessels, fat, the

lacrimal gland The lacrimal glands are paired exocrine glands, one for each eye, found in most terrestrial vertebrates and some marine mammals, that secrete the aqueous layer of the tear film. In humans, they are situated in the upper lateral region of each or ...

with its sac and duct, the

eyelid An eyelid is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. The human eyeli ...

s, medial and lateral palpebral ligaments, cheek ligaments, the

suspensory ligament A suspensory ligament is a ligament that supports a body part, especially an organ. Types include: * Suspensory ligament of axilla, also known as Gerdy's ligament * Cooper's ligaments, also known as the suspensory ligaments of Cooper or Suspensor ...

septum In biology, a septum (Latin for ''something that encloses''; plural septa) is a wall, dividing a cavity or structure into smaller ones. A cavity or structure divided in this way may be referred to as septate. Examples Human anatomy * Interatr ...

ciliary ganglion The ciliary ganglion is a bundle of nerve parasympathetic ganglion located just behind the eye in the posterior orbit. It is 1–2 mm in diameter and in humans contains approximately 2,500 neurons. The ganglion contains postganglionic parasympath ...

and

short ciliary nerves The short ciliary nerves are nerves of the orbit around the eye. They are branches of the ciliary ganglion. They supply parasympathetic and sympathetic nerve fibers to the ciliary muscle, iris, and cornea. Damage to the short ciliary nerve may ...

Structure

The orbits are conical or four-sided pyramidal cavities, which open into the midline of the face and point back into the head. Each consists of a base, an apex and four walls."eye, human."Encyclopædia Britannica from

Encyclopædia Britannica 2006 Ultimate Reference Suite DVD An encyclopedia (American English) or encyclopædia (British English) is a reference work or compendium providing summaries of knowledge either general or special to a particular field or discipline. Encyclopedias are divided into articles ...

2009

Openings

There are two important

foramina In anatomy and osteology, a foramen (;Entry "foramen"
in

, or windows, two important

fissure A fissure is a long, narrow crack opening along the surface of Earth. The term is derived from the Latin word , which means 'cleft' or 'crack'. Fissures emerge in Earth's crust, on ice sheets and glaciers, and on volcanoes. Ground fissure A ...

s, or grooves, and one

canal Canals or artificial waterways are waterways or engineered channels built for drainage management (e.g. flood control and irrigation) or for conveyancing water transport vehicles (e.g. water taxi). They carry free, calm surface fl ...

surrounding the

globe A globe is a spherical model of Earth, of some other celestial body, or of the celestial sphere. Globes serve purposes similar to maps, but unlike maps, they do not distort the surface that they portray except to scale it down. A model globe o ...

in the orbit. There is a

supraorbital foramen The supraorbital foramen, is a bony elongated opening located above the orbit (eye socket) and under the forehead. It is part of the frontal bone of the skull. The supraorbital foramen lies directly under the eyebrow. In some people this foramen i ...

, an

infraorbital foramen In human anatomy, the infraorbital foramen is one of two small holes in the skull's upper jawbone (maxillary bone), located below the eye socket and to the left and right of the nose. Both holes are used for blood vessels and nerves. In anatomica ...

, a

superior orbital fissure The superior orbital fissure is a foramen or cleft of the skull between the lesser and greater wings of the sphenoid bone. It gives passage to multiple structures, including the oculomotor nerve, trochlear nerve, ophthalmic nerve, abducens nerve ...

, an

inferior orbital fissure The inferior orbital fissure is formed by the sphenoid bone and the maxilla. It is located posteriorly along the boundary of the floor and lateral wall of the orbit. It transmits a number of structures, including: * the zygomatic branch of the m ...

and the

optic canal The ''optic foramen'' is the opening to the optic canal. The canal is located in the sphenoid bone; it is bounded medially by the body of the sphenoid and laterally by the lesser wing of the sphenoid. The superior surface of the sphenoid bone is b ...

, each of which contains structures that are crucial to normal eye functioning. The supraorbital foramen contains the supraorbital nerve, the first division of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewin ...

or V1 and lies just lateral to the

frontal sinus The frontal sinuses are one of the four pairs of paranasal sinuses that are situated behind the brow ridges. Sinuses are mucosa-lined airspaces within the bones of the face and skull. Each opens into the anterior part of the corresponding middle n ...

. The infraorbital foramen contains the second division of the trigeminal nerve, the

infraorbital nerve The infraorbital nerve is a branch of the maxillary nerve, itself a branch of the trigeminal nerve (CN V). It travels through the orbit and enters the infraorbital canal to exit onto the face through the infraorbital foramen. It provides sensory ...

or V2, and sits on the anterior wall of the

maxillary sinus The pyramid-shaped maxillary sinus (or antrum of Highmore) is the largest of the paranasal sinuses, and drains into the middle meatus of the nose through the osteomeatal complex.Human Anatomy, Jacobs, Elsevier, 2008, page 209-210 Structure It i ...

. Both foramina are crucial as potential pathways for cancer and infections of the orbit to spread into the brain or other deep facial structures. The

contains the (

cranial nerve II In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual information from the retina to the brain. In humans, the optic nerve is derived from ...

) and the

ophthalmic artery The ophthalmic artery (OA) is an artery of the head. It is the first branch of the internal carotid artery distal to the cavernous sinus. Branches of the ophthalmic artery supply all the structures in the orbit around the eye, as well as some str ...

, and sits at the junction of the sphenoid sinus with the ethmoid air cells, superomedial and posterior to structures at the orbital apex. It provides a pathway between the orbital contents and the

middle cranial fossa The middle cranial fossa, deeper than the anterior cranial fossa, is narrow medially and widens laterally to the sides of the skull. It is separated from the posterior fossa by the clivus and the petrous crest. It is bounded in front by the po ...

. The superior orbital fissure lies just

lateral Lateral is a geometric term of location which may refer to: Healthcare *Lateral (anatomy), an anatomical direction *Lateral cricoarytenoid muscle *Lateral release (surgery), a surgical procedure on the side of a kneecap Phonetics *Lateral cons ...

and inferior to the optic canal, and is formed at the junction of the lesser and

greater wing The greater wing of the sphenoid bone, or alisphenoid, is a bony process of the sphenoid bone; there is one on each side, extending from the side of the body of the sphenoid and curving upward, laterally, and backward. Structure The greater win ...

of the

sphenoid bone The sphenoid bone is an unpaired bone of the neurocranium. It is situated in the middle of the skull towards the front, in front of the basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the o ...

. It is a major pathway for intracranial communication, containing cranial nerves III, IV, VI which control eye movement via the

, and the ophthalmic branches of cranial nerve V, or V1. The second division of the trigeminal nerve enters the skull base at the

foramen rotundum The foramen rotundum is a circular hole in the sphenoid bone of the skull. It connects the middle cranial fossa and the pterygopalatine fossa. It allows for the passage of the maxillary nerve (V2), a branch of the trigeminal nerve. Structure T ...

, or V2. The inferior orbital fissure lies inferior and lateral to the ocular globe at the lateral wall of the maxillary sinus. It is not as important in function, though it does contain a few branches of the maxillary nerve and the infraorbital artery and vein. Other minor structures in the orbit include the

anterior Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...

and

posterior ethmoidal foramen Lateral to either olfactory groove are the internal openings of the anterior and posterior ethmoidal foramina (or canals). The posterior ethmoidal foramen opens at the back part of this margin under cover of the projecting lamina of the sphenoi ...

and zygomatic orbital foramen.

Bony walls

The bony walls of the orbital canal in humans do not derive from a single bone, but a mosaic of seven embryologically distinct structures: the

zygomatic bone In the human skull, the zygomatic bone (from grc, ζῠγόν, zugón, yoke), also called cheekbone or malar bone, is a paired irregular bone which articulates with the maxilla, the temporal bone, the sphenoid bone and the frontal bone. It is si ...

laterally, the

, with its lesser wing forming the optic canal and its greater wing forming the lateral posterior portion of the bony orbital process, the

maxillary bone The maxilla (plural: ''maxillae'' ) in vertebrates is the upper fixed (not fixed in Neopterygii) bone of the jaw formed from the fusion of two maxillary bones. In humans, the upper jaw includes the hard palate in the front of the mouth. The tw ...

inferiorly Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...

and medially which, along with the lacrimal and

ethmoid bone The ethmoid bone (; from grc, ἡθμός, hēthmós, sieve) is an unpaired bone in the skull that separates the nasal cavity from the brain. It is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to ...

s, forms the medial wall of the orbital canal. The ethmoid air cells are extremely thin, and form a structure known as the

lamina papyracea The orbital lamina of ethmoid bone, (or lamina papyracea or orbital lamina) is a smooth, oblong bone plate which forms the lateral surface of the labyrinth of the ethmoid bone in the skull. The plate covers in the middle and posterior ethmoidal ...

, the most delicate bony structure in the skull, and one of the most commonly fractured bones in orbital trauma. The lacrimal bone also contains the

nasolacrimal duct The nasolacrimal duct (also called the tear duct) carries tears from the lacrimal sac of the eye into the nasal cavity. The duct begins in the eye socket between the maxillary and lacrimal bones, from where it passes downwards and backwards. The o ...

. The superior bony margin of the orbital rim, otherwise known as the

orbital process In the human skull, the zygomatic bone (from grc, ζῠγόν, zugón, yoke), also called cheekbone or malar bone, is a paired irregular bone which articulates with the maxilla, the temporal bone, the sphenoid bone and the frontal bone. It is si ...

, is formed by the frontal bone. The roof (superior wall) is formed primarily by the orbital plate

frontal bone The frontal bone is a bone in the human skull. The bone consists of two portions.''Gray's Anatomy'' (1918) These are the vertically oriented squamous part, and the horizontally oriented orbital part, making up the bony part of the forehead, part ...

, and also the lesser wing of sphenoid near the apex of the orbit. The orbital surface presents medially by trochlear fovea and laterally by lacrimal fossa. The floor (inferior wall) is formed by the orbital surface of

maxilla The maxilla (plural: ''maxillae'' ) in vertebrates is the upper fixed (not fixed in Neopterygii) bone of the jaw formed from the fusion of two maxillary bones. In humans, the upper jaw includes the hard palate in the front of the mouth. The t ...

, the orbital surface of

and the minute orbital process of

palatine bone In anatomy, the palatine bones () are two irregular bones of the facial skeleton in many animal species, located above the uvula in the throat. Together with the maxillae, they comprise the hard palate. (''Palate'' is derived from the Latin ''pal ...

. Medially, near the orbital margin, is located the groove for

. Near the middle of the floor, located infraorbital groove, which leads to the infraorbital foramen. The floor is separated from the lateral wall by

, which connects the orbit to pterygopalatine and infratemporal fossa. The medial wall is formed primarily by the orbital plate of

ethmoid The ethmoid bone (; from grc, ἡθμός, hēthmós, sieve) is an unpaired bone in the skull that separates the nasal cavity from the brain. It is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to ...

, as well as contributions from the frontal process of maxilla, the

lacrimal bone The lacrimal bone is a small and fragile bone of the facial skeleton; it is roughly the size of the little fingernail. It is situated at the front part of the medial wall of the orbit. It has two surfaces and four borders. Several bony landmarks of ...

, and a small part of the body of the sphenoid. It is the thinnest wall of the orbit, evidenced by pneumatized ethmoidal cells. The lateral wall is formed by the frontal process of zygomatic and more posteriorly by the orbital plate of the greater wing of sphenoid. The bones meet at the zygomaticosphenoid suture. The lateral wall is the thickest wall of the orbit, important because it is the most exposed surface, highly vulnerable to blunt force trauma.

Borders

The base, orbital margin, which opens in the face, has four borders. The following bones take part in their formation: # Superior margin:

# Inferior margin:

and

# Medial margin:

and

# Lateral margin:

and

Function

The orbit holds and protects the

Eye movement

The movement of the eye is controlled by six distinct extraocular muscles, a

superior Superior may refer to: *Superior (hierarchy), something which is higher in a hierarchical structure of any kind Places *Superior (proposed U.S. state), an unsuccessful proposal for the Upper Peninsula of Michigan to form a separate state *Lake ...

, an inferior, a medial and a

rectus, as well as a

and an

inferior oblique The inferior oblique muscle or obliquus oculi inferior is a thin, narrow muscle placed near the anterior margin of the floor of the orbit. The inferior oblique is one of the extraocular muscles, and is attached to the maxillary bone (origin) and ...

. The superior ophthalmic vein is a sigmoidal vessel along the superior margin of the orbital canal that drains deoxygenated blood from surrounding musculature. The

is a crucial structure in the orbit, as it is often the only source of collateral blood to the brain in cases of large

internal carotid The internal carotid artery (Latin: arteria carotis interna) is an artery in the neck which supplies the anterior circulation of the brain. In human anatomy, the internal and external carotids arise from the common carotid arteries, where these ...

infarcts, as it is a collateral pathway to the

circle of Willis The circle of Willis (also called Willis' circle, loop of Willis, cerebral arterial circle, and Willis polygon) is a circulatory anastomosis that supplies blood to the brain and surrounding structures in reptiles, birds and mammals, including huma ...

. In addition, there is the

, which contains the optic nerve, or cranial nerve II, and is formed entirely by the lesser wing of the sphenoid, separated from the supraorbital fissure by the optic strut. Injury to any one of these structures by infection, trauma or neoplasm can cause temporary or permanent visual dysfunction, and even blindness if not promptly corrected. The orbits also protect the eye from mechanical injury.

Clinical significance

In the orbit, the surrounding fascia allows for smooth rotation and protects the orbital contents. If excessive tissue accumulates behind the ocular globe, the eye can protrude, or become exophthalmic. Enlargement of the

, located superotemporally within the orbit, produces protrusion of the eye inferiorly and medially (away from the location of the lacrimal gland). Lacrimal gland may be enlarged from

inflammation Inflammation (from la, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molec ...

(e.g. sarcoid) or

neoplasm A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...

(e.g.

lymphoma Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). In current usage the name usually refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enla ...

adenoid cystic carcinoma Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. This tumor most often occurs in the salivary glands, but it can also be found in many anatomic sites, including the breast, lacrimal gland, lung, brain ...

). Tumors (e.g.

glioma A glioma is a type of tumor that starts in the glial cells of the brain or the spine. Gliomas comprise about 30 percent of all brain tumors and central nervous system tumours, and 80 percent of all malignant brain tumours. Signs and symptoms ...

and

meningioma Meningioma, also known as meningeal tumor, is typically a slow-growing tumor that forms from the meninges, the membranous layers surrounding the brain and spinal cord. Symptoms depend on the location and occur as a result of the tumor pressing o ...

of the

optic nerve In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual information from the retina to the brain. In humans, the optic nerve is derived from ...

) within the cone formed by the horizontal rectus muscles produce axial protrusion (bulging forward) of the eye.

Graves disease Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyro ...

may also cause axial protrusion of the eye, known as

Graves' ophthalmopathy Graves’ ophthalmopathy, also known as thyroid eye disease (TED), is an autoimmune inflammatory disorder of the orbit and periorbital tissues, characterized by upper eyelid retraction, lid lag, swelling, redness (erythema), conjunctivitis, and b ...

, due to buildup of

extracellular matrix In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide struct ...

proteins and

fibrosis Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of perma ...

in the rectus muscles. Development of Graves' ophthalmopathy may be independent of thyroid function.

Additional images

File:Orbita2.jpg, Orbita File:Gray192.png, Medial wall of left orbit File:Gray787.png, Dissection showing origins of right ocular muscles, and nerves entering by the superior orbital fissure File:Orbita mensch.jpg File:Lateral orbit nerves.jpg, Lateral orbit nerves File:Temporal fossa.jpg, Orbital cavity

References

External links

* – "Arterial Supply, Orbit" * * *
Interactive tutorial at anatome.ncl.ac.uk
{{Authority control Skull Human eye anatomy