The enzyme exodeoxyribonuclease VII (EC 3.1.11.6, ''Escherichia coli'' exonuclease VII, ''E. coli'' exonuclease VII, endodeoxyribonuclease VII, exodeoxyribonuclease VII) is a
bacterial
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were amon ...
exonuclease enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
.
It is composed of two nonidentical subunits; one large subunit and 4 small ones.
that
catalyses exonucleolytic cleavage in either 5′- to 3′- or 3′- to 5′-direction to yield nucleoside 5′-phosphates. The large subunit also contains an
''N''-terminal OB-fold domain that binds to
nucleic acids.
References
{{Portal bar, Biology, border=no
Protein families
EC 3.1.11