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In
cardiovascular physiology Cardiovascular physiology is the study of the cardiovascular system The circulatory system, also called the cardiovascular system or the vascular system, is an organ system An organ system is a group of organs An organ is a group of tissu ...
, end-diastolic volume (EDV) is the volume of blood in the right and/or left ventricle at end load or filling in (
diastole Diastole ( ) is the part of the cardiac cycle and adjacent deflections. Re the cardiac cycle, ''atrial systole'' begins at the P wave; ''ventricular systole'' begins at the Q deflection of the QRS complex. The cardiac cycle is the performance ...
) or the amount of blood in the ventricles just before systole. Because greater EDVs cause greater distention of the ventricle, ''EDV'' is often used synonymously with '' preload'', which refers to the length of the
sarcomere A sarcomere (Greek σάρξ ''sarx'' "flesh", μέρος ''meros'' "part") is the smallest functional unit of striated muscle tissue Striated muscle tissue is a muscle tissue Muscle tissue is a soft tissue that composes muscles in animal bodi ...

sarcomere
s in
cardiac muscle Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate Vertebrates () comprise all species of animal Animals (also called Metazoa) are multicellular A multicellular organism is an organism ...

cardiac muscle
prior to contraction (
systole The systole ( ) is the part of the cardiac cycle The cardiac cycle is the performance of the human heart The heart is a cardiac muscle, muscular Organ (biology), organ in most animals, which pumps blood through the blood vessels of ...
). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (
stroke volume In cardiovascular physiologyCardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, unde ...
). __TOC__


Sample values

The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL. The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/ BSA and ranges between 60 and 100 mL/m2.


See also

* End-systolic volume *
Stroke volume In cardiovascular physiologyCardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, unde ...


References

{{DEFAULTSORT:End-Diastolic Volume Cardiovascular physiology