''N'',''N′''-Diisopropylcarbodiimide is a
carbodiimide used in
peptide synthesis. As a liquid, it is easier to handle than the commonly used
''N'',''N′''-dicyclohexylcarbodiimide, a waxy solid. In addition, ''N'',''N′''-diisopropylurea, its byproduct in many chemical reactions, is soluble in most
organic solvents, a property that facilitates
work-up
In chemistry, work-up refers to the series of manipulations required to isolate and purify the product(s) of a chemical reaction.
Typically, these manipulations may include:
* quenching a reaction to deactivate any unreacted reagents.
* coolin ...
.
Further reading
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Peptide coupling reagents
Carbodiimides
Reagents for biochemistry
Biochemistry
Biochemistry methods
Isopropyl compounds