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Aromatherapy is based on the usage of aromatic materials including
essential oils An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
and other
aroma compound An aroma compound, also known as an odorant, aroma, fragrance or flavoring, is a chemical compound that has a smell or odor. For an individual chemical or class of chemical compounds to impart a smell or fragrance, it must be sufficiently v ...
s, with claims for improving psychological and physical
well-being Well-being, or wellbeing, also known as wellness, prudential value or quality of life, refers to what is intrinsically valuable relative ''to'' someone. So the well-being of a person is what is ultimately good ''for'' this person, what is in th ...
. It is offered as a
complementary therapy Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
or as a form of alternative medicine, the first meaning alongside standard treatments, the second instead of conventional, evidence-based treatments. Aromatherapists, people who specialize in the practice of aromatherapy, utilize blends of supposedly therapeutic essential oils that can be used as topical application, massage, inhalation or water immersion. There is no good medical evidence that aromatherapy can either prevent, treat or cure any disease. Placebo-controlled trials are difficult to design as the point of aromatherapy is the smell of the products. There is disputed evidence that it may be effective in combating
postoperative nausea and vomiting Postoperative nausea and vomiting (PONV) is the phenomenon of nausea, vomiting, or retching experienced by a patient in the postanesthesia care unit (PACU) or within 24 hours following a surgical procedure. PONV affects about 10% of the population ...
.


History

The use of essential oils for therapeutic, spiritual, hygienic and ritualistic purposes goes back to ancient civilizations including the Indians, Chinese, Egyptians, Greeks, and Romans who used them in cosmetics, perfumes and drugs. Oils were used for aesthetic pleasure and in the beauty industry. They were a luxury item and a means of payment. It was believed the essential oils increased the shelf life of wine and improved the taste of food. Oils are described by
Dioscorides Pedanius Dioscorides ( grc-gre, Πεδάνιος Διοσκουρίδης, ; 40–90 AD), “the father of pharmacognosy”, was a Greek physician, pharmacologist, botanist, and author of '' De materia medica'' (, On Medical Material) —a 5-vo ...
, along with beliefs of the time regarding their healing properties, in his ''
De Materia Medica (Latin name for the Greek work , , both meaning "On Medical Material") is a pharmacopoeia of medicinal plants and the medicines that can be obtained from them. The five-volume work was written between 50 and 70 CE by Pedanius Dioscorides, ...
'', written in the first century. Distilled cedarwood oil was used by the ancient Egyptians, and the process of
distilling Distillation, or classical distillation, is the process of separating the components or substances from a liquid mixture by using selective boiling and condensation, usually inside an apparatus known as a still. Dry distillation is the heating ...
essential oils like rose essence was refined by the 11th century Persian scholar Ibn Sina.
Hildegard of Bingen Hildegard of Bingen (german: Hildegard von Bingen; la, Hildegardis Bingensis; 17 September 1179), also known as Saint Hildegard and the Sibyl of the Rhine, was a German Benedictine abbess and polymath active as a writer, composer, philosopher ...
used distilled lavender oil for medicinal treatments in the 12th century, and by the 15th century, oils were commonly distilled from various plant sources. In the era of modern medicine, the naming of this treatment first appeared in print in 1937 in a French book on the subject: ''Aromathérapie: Les Huiles Essentielles, Hormones Végétales'' by , a chemist. An English version was published in 1993. In 1910, Gattefossé burned a hand very badly and later claimed he treated it effectively with
lavender oil Lavender oil is an essential oil obtained by distillation from the flower spikes of certain species of lavender. There are over 400 types of lavender worldwide with different scents and qualities. Two forms of lavender oil are distinguished, '' ...
. A French surgeon, , pioneered the medicinal uses of essential oils, which he used as
antiseptic An antiseptic (from Greek ἀντί ''anti'', "against" and σηπτικός ''sēptikos'', "putrefactive") is an antimicrobial substance or compound that is applied to living tissue/skin to reduce the possibility of infection, sepsis, or putre ...
s in the treatment of wounded soldiers during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing ...
.


Choice and purchase

Aromatherapy products, and essential oils, in particular, may be regulated differently depending on their intended use. A product that is marketed with a therapeutic use in the US is regulated by the US Food & Drug Administration (FDA); a product with a cosmetic use is not (unless information shows that "it is unsafe when consumers use it according to directions on the label, or in the customary or expected way, or if it is not labeled properly".) The US Federal Trade Commission (FTC) regulates any aromatherapy advertising claims. There are no standards for determining the quality of essential oils in the United States; while the term "therapeutic grade" is in use, it does not have a regulatory meaning. Analysis using gas chromatography and mass spectrometry has been used to identify bioactive compounds in essential oils. These techniques are able to measure the levels of components to a few parts per billion. This does not make it possible to determine whether each component is natural or whether a poor oil has been "improved" by the addition of synthetic aromachemicals but the latter is often signalled by the minor impurities present. For example,
linalool Linalool () refers to two enantiomers of a naturally occurring terpene alcohol found in many flowers and spice plants. Linalool has multiple commercial applications, the majority of which are based on its pleasant scent (floral, with a touch of ...
made in plants will be accompanied by a small amount of hydro-linalool whilst synthetic linalool has traces of dihydro-linalool.


Effectiveness

There is no good medical evidence that aromatherapy can prevent or cure any disease. However, for cancer patients, aromatherapy tests showed mixed results in lowering anxiety and depression symptoms. In 2015, the Australian Government's Department of Health published the results of a review of alternative therapies that sought to determine if any were suitable for being covered by health insurance; aromatherapy was one of 17 therapies evaluated for which no clear evidence of effectiveness was found. * Evidence for the efficacy of aromatherapy in treating medical conditions is poor, with a particular lack of studies employing rigorous methodology. A number of systematic reviews have studied the clinical effectiveness of aromatherapy in respect to pain management in labor, the treatment of
post-operative nausea and vomiting Postoperative nausea and vomiting (PONV) is the phenomenon of nausea, vomiting, or retching experienced by a patient in the postanesthesia care unit (PACU) or within 24 hours following a surgical procedure. PONV affects about 10% of the population ...
, managing challenging behaviors in people suffering from
dementia Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affe ...
and symptom relief in
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
. However, some studies have come to the conclusion that while it does improve the patient's mood, there is no conclusive evidence on how it works with pain management. Studies have been inconclusive because no straightforward evidence exists. All of these reviews report a lack of evidence on the effectiveness of aromatherapy.


Safety concerns

Aromatherapy carries a number of risks of
adverse effects An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complica ...
and with this in consideration, combined with the lack of evidence of its therapeutic benefit, makes the practice of questionable worth. Many studies exploring the concerns that essential oils are highly concentrated and can irritate the skin when used in undiluted form often referred to as neat application. Therefore, they are normally diluted with a carrier oil for topical application such as
jojoba oil Jojoba oil is the liquid produced in the seed of the ''Simmondsia chinensis'' ( jojoba) plant, a shrub, which is native to southern Arizona, southern California, and northwestern Mexico. The oil makes up approximately 50% of the jojoba seed by w ...
, olive oil, sweet almond oil or coconut oil.
Phototoxic Phototoxicity, also called photoirritation, is a chemically induced skin irritation, requiring light, that does not involve the immune system. It is a type of photosensitivity. The skin response resembles an exaggerated sunburn. The involved chemi ...
reactions may occur with many cold pressed
citrus ''Citrus'' is a genus of flowering trees and shrubs in the rue family, Rutaceae. Plants in the genus produce citrus fruits, including important crops such as oranges, lemons, grapefruits, pomelos, and limes. The genus ''Citrus'' is native to ...
peel oils such as lemon or
lime Lime commonly refers to: * Lime (fruit), a green citrus fruit * Lime (material), inorganic materials containing calcium, usually calcium oxide or calcium hydroxide * Lime (color), a color between yellow and green Lime may also refer to: Botany ...
. Also, many essential oils have chemical components that are sensitisers (meaning that they will, after a number of uses, cause reactions on the skin and more so in the rest of the body). Chemical composition of essential oils could be affected by herbicides if the original plants are cultivated versus wild-harvested. Some oils can be toxic to some domestic animals, with cats being particularly prone. Most oils can be toxic to humans as well. A report of three cases documented gynecomastia in prepubertal boys who were exposed to topical lavender and
tea tree oil Tea tree oil, also known as melaleuca oil, is an essential oil with a fresh camphoraceous odor and a colour that ranges from pale yellow to nearly colourless and clear. It is derived from the leaves of the tea tree, '' Melaleuca alternifolia'', ...
s. The Aromatherapy Trade Council of the UK issued a rebuttal. The Australian Tea Tree Association, a group that promotes the interests of Australian tea tree oil producers, exporters and manufacturers issued a letter that questioned the study and called on the ''
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. His ...
'' for a retraction. Another article published by a different research group also documented three cases of
gynecomastia Gynecomastia (also spelled gynaecomastia) is the abnormal non-cancerous enlargement of one or both breasts in males due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens. Updated by Brent Wisse ( ...
in prepubertal boys who were exposed to topical lavender oil. A recent research, made by
NIEHS The National Institute of Environmental Health Sciences (NIEHS) conducts research into the effects of the environment on human disease, as one of the 27 institutes and centers of the National Institutes of Health (NIH). It is located in the Rese ...
scientists and published on Endocrine Society's ''
Journal of Clinical Endocrinology and Metabolism ''The Journal of Clinical Endocrinology and Metabolism'' is a peer-reviewed medical journal in the field of endocrinology and metabolism. The current editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publ ...
'', concluded that persistent exposure to lavender products is associated with premature breast development in girls and "that chemicals in lavender oil and tea tree oil are potential
endocrine disruptors Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause ca ...
with varying effects on receptors for two hormones —
estrogen Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal ac ...
and
androgen An androgen (from Greek ''andr-'', the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This in ...
". Essential oils can be extremely toxic when ingested or absorbed internally. Doses as low as 2 ml have been reported to cause clinically significant symptoms and severe poisoning can occur after ingestion of as little as 4 ml. A few reported cases of toxic reactions like
liver The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it ...
damage and seizures have occurred after ingestion of sage, hyssop, thuja and cedar oils. Accidental ingestion may happen when oils are not kept out of reach of children. As with any bioactive substance, an essential oil that may be safe for the general public could still pose hazards for pregnant and lactating women. Oils both ingested and applied to the skin can potentially have negative interactions with conventional medicine. For example, the topical use of
methyl salicylate Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often a ...
-heavy oils like
wintergreen Wintergreen is a group of aromatic plants. The term "wintergreen" once commonly referred to plants that remain green (continue photosynthesis) throughout the winter. The term "evergreen" is now more commonly used for this characteristic. Most ...
may cause bleeding in users taking the anticoagulant
warfarin Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner). It is commonly used to prevent blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent st ...
. In late 2021, an aromatherapy spray was recalled after it was found to be contaminated with ''
Burkholderia pseudomallei ''Burkholderia pseudomallei'' (also known as ''Pseudomonas pseudomallei'') is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It is a soil-dwelling bacterium endemic in tropical and subtropical regions worldwide, particularly in T ...
'', the bacteria that causes
melioidosis Melioidosis is an infectious disease caused by a gram-negative bacterium called ''Burkholderia pseudomallei''. Most people exposed to ''B. pseudomallei'' experience no symptoms; however, those who do experience symptoms have signs and symptoms t ...
, which led to four cases of the disease and two deaths.


See also

* Aromachologist * List of unproven and disproven cancer treatments


References


External links


Aromatherapy and Essential Oils
– health professional
patient
PDQ (Physician Data Query) summaries from the
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
* {{Authority control Herbalism Mind–body interventions Fringe science Alternative medicine