Centenarian
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A centenarian is a
person A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, ...
who has reached the age of 100 years. Because
life expectancies Life expectancy is a statistical measure of the average time an organism is expected to live, based on the year of its birth, current age, and other demographic factors like sex. The most commonly used measure is life expectancy at birth ...
worldwide are below 100, the term is invariably associated with
longevity The word " longevity" is sometimes used as a synonym for "life expectancy" in demography. However, the term ''longevity'' is sometimes meant to refer only to especially long-lived members of a population, whereas ''life expectancy'' is always d ...
. The
United Nations The United Nations (UN) is an intergovernmental organization whose stated purposes are to maintain international peace and international security, security, develop friendly relations among nations, achieve international cooperation, and be ...
estimated that there were 316,600 living centenarians worldwide in 2012, and 573,000 in 2020, almost quadruple the 2000 estimate of 151,000. As
world population In demographics, the world population is the total number of humans currently living. It was estimated by the United Nations to have exceeded 8 billion in November 2022. It took over 200,000 years of human prehistory and history for the ...
and life expectancy continue to increase, the number of centenarians is expected to increase substantially in the twenty-first century. According to the Office of National Statistics in the United Kingdom, one-third of babies born in the country in 2013 are expected to live to 100. According to a 1998 United Nations demographic survey, Japan is expected to have 272,000 centenarians by 2050; other sources suggest that the number could be closer to 1 million. The incidence of centenarians in Japan was one per 3,522 people in 2008. In Japan, the number of centenarians is highly skewed towards females. Japan in fiscal year 2016 had 57,525 female centenarians, while there were 8,167 males, a ratio of 7:1. The increase of centenarians was even more skewed at 11.6:1.


Worldwide incidence by country

The total number of centenarians in the world is uncertain. Th
Population Division
of the United Nations estimated that there were 23,000 in 1950, 110,000 in 1990, 150,000 in 1995, 209,000 in 2000, 324,000 in 2005, 455,000 in 2009,"World Population Ageing 2009"
(PDF) ST/ESA/SER.A/295. Population Division – Department of Economic and Social Affairs. United Nations. October 2010. p.27.
and 935,000 in 2024. These older estimates, however, did not take into account downward adjustments of national estimates made by several countries such as the United States. The UN estimated in 2012, as a result of these adjustments, that there were only 316,600 centenarians worldwide. The following table gives estimated centenarian populations by country, including both the latest and the earliest known estimates, where available.


Supercentenarians

A
supercentenarian A supercentenarian (sometimes hyphenated as super-centenarian) is a person who has reached the age of 110 years. This age is achieved by about one in 1,000 centenarians. Supercentenarians typically live a life free of major age-related diseases u ...
, sometimes hyphenated as super-centenarian, is a person who has reached the age of 110 years. This age milestone is only achieved by about one in a thousand centenarians. Even rarer is a person who has lived to 115. There are 72 people in
recorded history Recorded history or written history describes the historical events that have been recorded in a written form or other documented communication which are subsequently evaluated by historians using the historical method. For broader world hist ...
who have indisputably reached 115. Only three of the people who have reached 115 are men. Maria Branyas, Tomiko Itooka,
Inah Canabarro Lucas Inah Canabarro Lucas (also known as Sister Inah; born 8 June 1908) is a Brazilian nun and supercentenarian who has been the world's oldest living nun since the death of Lucile Randon on 17 January 2023. Biography Canabarro was born on 8 June ...
and Elizabeth Francis are the only verified people currently alive who have reached the 115 years milestone.
Jeanne Calment Jeanne Louise Calment (; 21 February 1875 – 4 August 1997) was a French supercentenarian and the oldest human whose age is documented, with a lifespan of 122 years and 164 days. Her longevity attracted media attention and medical studies ...
from
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pac ...
is the only age-verified person in human history to have reached the age of 120 years.


Recognition and congratulations


History, blessings and traditions

An aspect of
blessing In religion, a blessing (also used to refer to bestowing of such) is the impartation of something with grace, holiness, spiritual redemption, or divine will. Etymology and Germanic paganism The modern English language term ''bless'' likely ...
in many cultures is to offer a wish that the recipient lives to 100 years old. Among
Hindu Hindus (; ) are people who religiously adhere to Hinduism.Jeffery D. Long (2007), A Vision for Hinduism, IB Tauris, , pages 35–37 Historically, the term has also been used as a geographical, cultural, and later religious identifier for ...
s in India, where touching feet of elders and respected is a tradition, people who touch the feet of elders are often blessed with "May you live a hundred years". In Sweden, the traditional birthday song states, ''May he/she live for one hundred years''. In
Judaism Judaism ( he, ''Yahăḏūṯ'') is an Abrahamic, monotheistic, and ethnic religion comprising the collective religious, cultural, and legal tradition and civilization of the Jewish people. It has its roots as an organized religion in the ...
, ''May you live to be 120 years old'' is a common blessing. In Poland, ''
Sto lat ''Sto lat'' (One Hundred Years) is a traditional Poland, Polish song that is sung to express good wishes, good health and long life to a person. It is also a common way of wishing someone a happy birthday in Polish. ''Sto lat'' is used in many bi ...
'', a wish to live a hundred years, is a traditional form of praise and good wishes, and the song "sto lat, sto lat" is sung on the occasion of the birthday celebrations—arguably, it is the most popular song in Poland and among Poles around the globe. According to legends,
Sage Sage or SAGE may refer to: Plants * ''Salvia officinalis'', common sage, a small evergreen subshrub used as a culinary herb ** Lamiaceae, a family of flowering plants commonly known as the mint or deadnettle or sage family ** ''Salvia'', a large ...
s from ancient India lived and meditated for tens of thousands of years while Great Kings ruled their kingdoms for thousands of years.
Chinese emperors ''Huangdi'' (), translated into English as Emperor, was the superlative title held by monarchs of China who ruled various imperial regimes in Chinese history. In traditional Chinese political theory, the emperor was considered the Son of Heaven ...
were hailed to live ten thousand years, while empresses were hailed to live a thousand years. In Italy, "A hundred of these days!" (''cento di questi giorni'') is an
augury Augury is the practice from ancient Roman religion of interpreting omens from the observed behavior of birds. When the individual, known as the augur, interpreted these signs, it is referred to as "taking the auspices". "Auspices" (Latin ''aus ...
for birthdays, to live to celebrate 100 more birthdays. Some Italians say "A cent'anni!", which means "(up) To a hundred years", in that they wish that they could all live happily for a hundred years. In Greece, wishing someone Happy Birthday ends with the expression (), which can be loosely translated as "may you make it one hundred birthdays". In Sri Lanka, it is a custom to bless as "you may live 220 instead of 120". In many countries, people receive a gift or congratulations from federal/state institutions on their 100th birthday.


United States

As of 2019, there were an estimated 72,000 centenarians living in the U.S.; the 2020 census officially counted 80,139, and the 2010 census had 53,364.''Mortality'' by Richard Saul Wurman and Nigel Holmes, p. 41, 2019. ISBN 978-0-578-50305-9 However, the U.S. Census Bureau claimed in 1999 that as many as a third of people stating their age as over 100 might be exaggerating. In the United States, centenarians may request a letter of congratulation from the
United States president The president of the United States (POTUS) is the head of state and head of government of the United States of America. The president directs the executive branch of the federal government and is the commander-in-chief of the United State ...
to mark their longevity. ''Today'' also presents a segment honoring centenarians and older, sponsored by
Smuckers The J.M. Smucker Company, also known as Smuckers, is an American manufacturer of food and beverage products. Headquartered in Orrville, Ohio, the company was founded in 1897 as a maker of apple butter. J.M. Smucker currently has three major bus ...
. The tradition was created in 1983 by weather presenter Willard Scott, and is now presented by his successor Al Roker.


Asia

Japanese centenarians receive a silver cup and a certificate from the
prime minister of Japan The prime minister of Japan (Japanese: 内閣総理大臣, Hepburn: ''Naikaku Sōri-Daijin'') is the head of government of Japan. The prime minister chairs the Cabinet of Japan and has the ability to select and dismiss its Ministers of Stat ...
upon the
Respect for the Aged Day is a public holiday in Japan celebrated annually to honor elderly citizens. It started in 1966 as a national holiday and was held on every September 15. Since 2003, Respect for the Aged Day is held on the third Monday of September due to the Ha ...
following their 100th birthday, honouring them for their longevity and prosperity in their lives. In
Madhya Pradesh Madhya Pradesh (, ; meaning 'central province') is a state in central India. Its capital is Bhopal, and the largest city is Indore, with Jabalpur, Ujjain, Gwalior, Sagar, and Rewa being the other major cities. Madhya Pradesh is the seco ...
,
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
, the award known as
Shatayu Samman Shatayu Samman is an award given to persons who lived for a century, by the Government of Madhya Pradesh Madhya Pradesh (, ; meaning 'central province') is a state in central India. Its capital is Bhopal, and the largest city is Indore, w ...
is given out to people who live at least 100 years to promote awareness of good health. North Korean centenarians receive a birthday congratulatory letter from the Supreme Leader of the DPRK. On 6 July 2022, Pak Hak Sil, a centenarian living in Koup-ri of
Kangnam County Kangnam County is one of the two suburban counties of Pyongyang, North Korea. It is north-west of Songrim, north-east of Hwangju County, west of Chunghwa County, and south of Nakrang-guyok. It is the location of cooperative farms and smaller ind ...
,
Pyongyang Pyongyang (, , ) is the capital and largest city of North Korea, where it is known as the "Capital of the Revolution". Pyongyang is located on the Taedong River about upstream from its mouth on the Yellow Sea. According to the 2008 populatio ...
, received a birthday letter sent by Kim Jong Un. In Taiwan, people aged 100 or above receive a golden pendant necklace on Chong Yang Festival each year from the
president President most commonly refers to: *President (corporate title) *President (education), a leader of a college or university *President (government title) President may also refer to: Automobiles * Nissan President, a 1966–2010 Japanese ful ...
and Ministry of Health and Welfare.


Europe

German centenarians receive a letter of congratulations from the
president of Germany The president of Germany, officially the Federal President of the Federal Republic of Germany (german: link=no, Bundespräsident der Bundesrepublik Deutschland),The official title within Germany is ', with ' being added in international corres ...
. In Ireland, centenarians can receive a €2,540 "Centenarians' Bounty" and a letter from the
president of Ireland The president of Ireland ( ga, Uachtarán na hÉireann) is the head of state of Republic of Ireland, Ireland and the supreme commander of the Defence Forces (Ireland), Irish Defence Forces. The president holds office for seven years, and can ...
, even if they are resident abroad. Irish people celebrating their 101st birthday may also receive a special silver minted coin with a quote by a famous Irish writer or poet. Centenarians born in Italy receive a letter of congratulations from the president of Italy. In the Netherlands,
the monarch This is a list of main and recurring fictional characters from ''The Venture Bros.'', a comic science fiction television series broadcast on Adult Swim. Overview Team Venture Team Venture comprises the central characters in the show; they for ...
and their commissioner sends a letter on the 100th birthday and on every birthday beginning with the 105th. Swedish centenarians receive a telegram from the king and queen of Sweden.


British and Commonwealth realms

In
Commonwealth realm A Commonwealth realm is a sovereign state in the Commonwealth of Nations whose monarch and head of state is shared among the other realms. Each realm functions as an independent state, equal with the other realms and nations of the Commonwealt ...
s including the United Kingdom, Canada, Australia and New Zealand centenarians can receive congratulations card greetings from the
monarch A monarch is a head of stateWebster's II New College DictionarMonarch Houghton Mifflin. Boston. 2001. p. 707. Life tenure, for life or until abdication, and therefore the head of state of a monarchy. A monarch may exercise the highest authority ...
King Charles III on their 100th birthday. In the UK, greeting cards are also sent by the monarch on every birthday beginning with the 105th. In Commonwealth realms in which the monarch does not ordinarily reside, honorees can also receive congratulations from the
governor-general Governor-general (plural ''governors-general''), or governor general (plural ''governors general''), is the title of an office-holder. In the context of governors-general and former British colonies, governors-general are appointed as viceroy t ...
. In Canada, application must be made through the GGS official website. Similarly, in New Zealand, honorees must apply for greetings through the official government website.


British traditions

The traditions of British centenarians receiving greetings and congratulations was established by
King Edward VII Edward VII (Albert Edward; 9 November 1841 – 6 May 1910) was King of the United Kingdom of Great Britain and Ireland and Emperor of India, from 22 January 1901 until his death in 1910. The second child and eldest son of Queen Victoria a ...
in 1908. The famous acrobat and
tightrope walker Tightrope walking, also called funambulism, is the skill of walking along a thin wire or rope. It has a long tradition in various countries and is commonly associated with the circus. Other skills similar to tightrope walking include slack rope ...
Henry Johnson received a congratulatory letter from Edward VII via his royal courtier
Viscount Knollys Viscount Knollys (), of Caversham in the County of Oxford, is a title in the Peerage of the United Kingdom. It was created in 1911 for the court official Francis Knollys, 1st Baron Knollys, Private Secretary to the Sovereign from 1901 to 19 ...
in 1906. The tradition of royal congratulations continued in 1908, when the secretary for King Edward VII sent a congratulatory letter to Reverend Thomas Lord of
Horncastle Horncastle is a town and civil parish in the East Lindsey district in Lincolnshire, east of Lincoln. Its population was 6,815 at the 2011 census and estimated at 7,123 in 2019. A section of the ancient Roman walls remains. History Romans Alt ...
, Lincolnshire, in a newspaper clipping, declaring, "I am commanded by the King to congratulate you on the attainment of your hundredth year, after a most useful life". The practice was formalised from 1917, under the reign of King
George V George V (George Frederick Ernest Albert; 3 June 1865 – 20 January 1936) was King of the United Kingdom and the British Dominions, and Emperor of India, from 6 May 1910 until Death and state funeral of George V, his death in 1936. Born duri ...
, who also sent congratulations then sent by a telegram on the attainment of a diamond wedding anniversary (or jubilee) marking 60 years of marriage. During the reign of King George V, only 24 telegrams were sent; however, with the aging population, this increased to 273 during 1952, when the longest-reigning monarch Queen
Elizabeth II Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until her death in 2022. She was queen regnant of 32 sovereign states during ...
ascended the throne. The Queen also sent a telegram, and later a portrait-style greeting card with the notation, "I am so pleased to know that you are celebrating your one hundredth birthday. I send my congratulations and best wishes to you on such a special occasion." Each few years the card was updated with a current updated picture of the Queen to ensure people did not receive the same card more than once. The Queen further sent her congratulations on one's 105th birthday and every year thereafter as well as on special wedding anniversaries.


Centenarians in antiquity

While the number of centenarians per capita was much lower in ancient times than today, the data suggest that they were not unheard of. Estimates of
life expectancy Life expectancy is a statistical measure of the average time an organism is expected to live, based on the year of its birth, current age, and other demographic factors like sex. The most commonly used measure is life expectancy at birth ...
in antiquity are far lower than modern values mostly due to the far greater incidence of deaths in infancy or childhood. Those who lived past early childhood had a reasonable chance of living to a relatively old age. The assumption of what constitutes "old age", or being "elderly", at least, seems to have remained unchanged since antiquity, the line being generally drawn at either sixty or sixty-five years;
Psalm 90 Psalm 90 is the 90th psalm from the Book of Psalms and the opening psalm of Book 4 of the psalms. Uniquely among the Psalms, it is attributed to Moses. It is well known for its reference in verse 10 to human life expectancy being 70 or 80 ("thre ...
:10 in the
Hebrew Bible The Hebrew Bible or Tanakh (;"Tanach"
''Random House Webster's Unabridged Dictionary''.
Hebrew: ''Tān ...
appears to give seventy to eighty years as the natural life expectancy of a person surviving into old age, "The years of our life are seventy, or even by reason of strength eighty". A survey of the lifespans of male individuals with entries in the '' Oxford Classical Dictionary'' (i.e., a sample pre-selected to include those who lived long enough to attain historical notability) found a median lifespan of 72 years, and a range of 32 to 107 years, for 128 individuals born before 100 BC (though the same study found a median lifespan of 66 years for 100 individuals born after 100 BC but no later than 602 AD); by comparison, male individuals listed in ''Chambers Biographical Dictionary'' who died between 1900 and 1949 had a median lifespan of 71.5 years, with a range between 29 and 105 years. The author of the 1994 study concluded that it was only in the second half of the 20th century that medical advances have extended the life expectancy of those who live into adulthood. Reliable references to individuals in antiquity who lived past 100 years are quite rare, but they do exist. For instance, Cicero's wife
Terentia Terentia (; 98 BC – AD 6) was the wife of the renowned orator Marcus Tullius Cicero. She was instrumental in Cicero's political life both as a benefactor and as a fervent activist for his cause. Family background Terentia was born into a wea ...
was reported by
Pliny the Elder Gaius Plinius Secundus (AD 23/2479), called Pliny the Elder (), was a Roman author, naturalist and natural philosopher, and naval and army commander of the early Roman Empire, and a friend of the emperor Vespasian. He wrote the encyclopedic '' ...
to have lived from 98 BC to 6 AD, 104 years. Regnal dates of Bronze Age monarchs are notoriously unreliable; the sixth dynasty Egyptian ruler
Pepi II Pepi II Neferkare (2284 BC – after 2247 BC, probably either  2216 or  2184 BC) was a pharaoh of the Sixth Dynasty in Egypt's Old Kingdom who reigned from  2278 BC. His second name, Neferkare (''Nefer-ka-Re''), means "Beautiful is ...
is sometimes listed as having lived , as he is said to have reigned for 94 years, but alternative readings cite a reign of just 64 years.
Adad-guppi Adad-guppi (Babylonian cuneiform: ''Adad-gûppîʾ''; c. 648-544 BC), also known as Addagoppe, was an Assyrian priestess, a devotee of the moon god Sîn in the northern Assyrian city of Harran, and the mother of King Nabonidus (ruled 556–39 BC ...
, mother of the last king of the
Neo-Babylonian Empire The Neo-Babylonian Empire or Second Babylonian Empire, historically known as the Chaldean Empire, was the last polity ruled by monarchs native to Mesopotamia. Beginning with the coronation of Nabopolassar as the List of kings of Babylon, King of B ...
Nabonidus Nabonidus (Babylonian cuneiform: ''Nabû-naʾid'', meaning "May Nabu be exalted" or "Nabu is praised") was the last king of the Neo-Babylonian Empire, ruling from 556 BC to the fall of Babylon to the Achaemenid Empire under Cyrus the Great in 539 ...
apparently lived from -544 BC (c. 104 years) according to inscriptions on funeral
stele A stele ( ),Anglicized plural steles ( ); Greek plural stelai ( ), from Greek , ''stēlē''. The Greek plural is written , ''stēlai'', but this is only rarely encountered in English. or occasionally stela (plural ''stelas'' or ''stelæ''), whe ...
s.
Diogenes Laërtius Diogenes Laërtius ( ; grc-gre, Διογένης Λαέρτιος, ; ) was a biographer of the Ancient Greece, Greek philosophers. Nothing is definitively known about his life, but his surviving ''Lives and Opinions of Eminent Philosophers'' is a ...
() gives one of the earliest references regarding the plausible centenarian longevity given by a scientist, the astronomer
Hipparchus Hipparchus (; el, Ἵππαρχος, ''Hipparkhos'';  BC) was a Greek astronomer, geographer, and mathematician. He is considered the founder of trigonometry, but is most famous for his incidental discovery of the precession of the equi ...
of Nicaea (), who, according to the doxographer, said that the philosopher
Democritus of Abdera Democritus (; el, Δημόκριτος, ''Dēmókritos'', meaning "chosen of the people"; – ) was an Ancient Greek pre-Socratic philosopher from Abdera, primarily remembered today for his formulation of an atomic theory of the universe. No ...
() lived 109 years. Other ancient accounts of Democritus agree that the philosopher lived at least 90 years. The case of Democritus differs from those of, for example,
Epimenides Epimenides of Cnossos (or Epimenides of Crete) (; grc-gre, Ἐπιμενίδης) was a semi-mythical 7th or 6th century BC Greek seer and philosopher-poet, from Knossos or Phaistos. Life While tending his father's sheep, Epimenides is said to ...
of Crete (7th and 6th centuries BC), who is said to have lived an implausible 154, 157, or 290 years, depending on the source. Other ancient Greek philosophers thought to have lived beyond the age of 90 include Xenophanes of Colophon (),
Pyrrho Pyrrho of Elis (; grc, Πύρρων ὁ Ἠλεῖος, Pyrrhо̄n ho Ēleios; ), born in Elis, Greece, was a Greek philosopher of Classical antiquity, credited as being the first Greek skeptic philosopher and founder of Pyrrhonism. Life ...
of Ellis (), and
Eratosthenes Eratosthenes of Cyrene (; grc-gre, Ἐρατοσθένης ;  – ) was a Greek polymath: a mathematician, geographer, poet, astronomer, and music theorist. He was a man of learning, becoming the chief librarian at the Library of Alexandria ...
of Cirene (). Also, the Greek rhetorician Isocrates of Athens (436-338 BC) lived 97/98 years and the famous Greek tragedian Sophocles (497/496-406/405 BC) lived at least 90 years. Hosius of Córdoba, the man who convinced
Constantine the Great Constantine I ( , ; la, Flavius Valerius Constantinus, ; ; 27 February 22 May 337), also known as Constantine the Great, was Roman emperor from AD 306 to 337, the first one to Constantine the Great and Christianity, convert to Christiani ...
to call the First Council of Nicaea, reportedly lived to age 102. A rare record of an ordinary person who lived to be a centenarian is the tombstone of Roman British legionary veteran Julius Valens, inscribed "VIXIT ANNIS C". In the medieval period, Albert Azzo II, Margrave of Milan (d. 1097) is said by
Bernold of Constance Bernold of Constance (c. 1054–Schaffhausen, September 16, 1100) was a chronicler and writer of tracts, and a defender of the Church reforms of Pope Gregory VII. Life He was educated at Constance under the renowned teacher Bernard of Const ...
to have lived past 100 years (''iam maior centenario'').


Research

Research in Italy suggests that healthy centenarians have high levels of both
vitamin A Vitamin A is a fat-soluble vitamin and an essential nutrient for humans. It is a group of organic compounds that includes retinol, retinal (also known as retinaldehyde), retinoic acid, and several provitamin A carotenoids (most notably bet ...
and
vitamin E Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitami ...
and that this seems to be important in causing their extreme longevity. Other research contradicts this, however, and has found that this theory does not apply to centenarians from
Sardinia Sardinia ( ; it, Sardegna, label=Italian, Corsican and Tabarchino ; sc, Sardigna , sdc, Sardhigna; french: Sardaigne; sdn, Saldigna; ca, Sardenya, label=Algherese and Catalan) is the second-largest island in the Mediterranean Sea, after ...
, for whom other factors probably play a more important role. A preliminary study carried out in Poland showed that, in comparison with young healthy female adults, centenarians living in Upper Silesia had significantly higher red blood cell glutathione reductase and
catalase Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a very important enzyme in protecting t ...
activities, although serum levels of
vitamin E Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitami ...
were not significantly higher. Researchers in Denmark have also found that centenarians exhibit a high activity of glutathione reductase in red blood cells. In this study, the centenarians having the best cognitive and physical functional capacity tended to have the highest activity of this
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
. Other research has found that people whose parents became centenarians have an increased number of naïve
B cell B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or ...
s. It is well known that the children of parents who have a long life are also likely to reach a healthy age, but it is not known why, although the inherited genes are probably important. A variation in the gene
FOXO3 Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the ''FOXO3'' gene. Function FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-bin ...
A is known to have a positive effect on the life expectancy of humans, and is found much more often in people living to 100 and beyond – moreover, this appears to be true worldwide. Men and women who are 100 or older tend to have extroverted personalities, according to Thomas T. Perls, the director of the New England Centenarian Study at Boston University. Centenarians will often have many friends, strong ties to relatives and high self-esteem. In addition, some research suggests that the offspring of centenarians are more likely to age in better cardiovascular health than their peers.


DNA repair

Lymphoblastoid cell lines established from blood samples of centenarians have significantly higher activity of the DNA repair protein PARP ( Poly ADP ribose polymerase) than cell lines from younger (20 to 70 years old) individuals. The lymphocytic cells of centenarians have characteristics typical of cells from young people, both in their capability of priming the mechanism of repair after H2O2 sublethal oxidative DNA damage and in their PARP capacity. PARP activity measured in the permeabilized mononuclear
leukocyte White blood cells, also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from mult ...
blood cells of thirteen
mammal Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...
ian species correlated with maximum lifespan of the species. These findings suggest that PARP mediated DNA repair activity contributes to the longevity of centenarians, consistent with the DNA damage theory of aging.


Japanese bio-study

Many experts attribute Japan's high life expectancy to the typical Japanese diet, which is particularly low in refined simple carbohydrates, and to hygienic practices. The number of centenarians in relation to the total population was, in September 2010, 114% higher in
Shimane Prefecture is a prefecture of Japan located in the Chūgoku region of Honshu. Shimane Prefecture is the second-least populous prefecture of Japan at 665,205 (February 1, 2021) and has a geographic area of 6,708.26 km2. Shimane Prefecture borders Yamaguc ...
than the national average. This ratio was also 92% higher in
Okinawa Prefecture is a prefecture of Japan. Okinawa Prefecture is the southernmost and westernmost prefecture of Japan, has a population of 1,457,162 (as of 2 February 2020) and a geographic area of 2,281 km2 (880 sq mi). Naha is the capital and largest city o ...
.Santrock, John (2008). "Physical Development and Biological Aging". In Mike Ryan, Michael J. Sugarman, Maureen Spada, and Emily Pecora (eds.): ''A Topical Approach to Life-Span Development'' (pp. 129-132). New York: McGraw-Hill Companies, Inc. In Okinawa, studies have shown five factors that have contributed to the large number of centenarians in that region: # A diet that is heavy on grains, fish, and vegetables and light on meat, eggs, and dairy products. # Low-stress lifestyles, which are proven significantly less stressful than that of the mainland inhabitants of Japan. # A caring community, where older adults are not isolated and are taken better care of. # High levels of activity, where locals work until an older age than the average age in other countries, and more emphasis on activities like walking and gardening to keep active. # Spirituality, where a sense of purpose comes from involvement in spiritual matters and prayer eases the mind of stress and problems. Although these factors vary from those mentioned in the previous study, the culture of Okinawa has proven these factors to be important in its large population of centenarians. A historical study from Korea found that male
eunuchs A eunuch ( ) is a male who has been castrated. Throughout history, castration often served a specific social function. The earliest records for intentional castration to produce eunuchs are from the Sumerian city of Lagash in the 2nd millennium ...
in the royal court had a centenarian rate of over 3%, and that eunuchs lived on average 14 to 19 years longer than uncastrated men.


Epigenetic studies

By measuring the biological age of various tissues from centenarians, researchers may be able to identify tissues that are protected from aging effects. According to a study of 30 different body parts from centenarians and younger controls, the
cerebellum The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebel ...
is the youngest brain region (and probably body part) in centenarians (about 15 years younger than expected) according to an epigenetic biomarker of tissue age known as
epigenetic clock An epigenetic clock is a biochemical test that can be used to measure age. The test is based on DNA methylation levels, measuring the accumulation of methyl groups to one's DNA molecules. History The strong effects of age on DNA methylation le ...
. These findings could explain why the cerebellum exhibits fewer neuropathological hallmarks of age related dementias compared to other brain regions. Further, the offspring of semi-supercentenarians (subjects who reached an age of 105–109 years) have a lower epigenetic age than age-matched controls (age difference=5.1 years in peripheral blood mononuclear cells) and centenarians are younger (8.6 years) than expected based on their chronological age.


Media references

Centenarians are often the subject of news stories, which often focus on the fact that they are over 100 years old. Along with the typical birthday celebrations, these reports provide researchers and cultural historians with evidence as to how the rest of society views this elderly population. Some examples: * William A. Del Monte, 109 years old, was the last known survivor of the
1906 San Francisco earthquake At 05:12 Pacific Standard Time on Wednesday, April 18, 1906, the coast of Northern California was struck by a major earthquake with an estimated moment magnitude of 7.9 and a maximum Mercalli intensity of XI (''Extreme''). High-intensity sha ...
. He died in a nursing facility, in
Marin County Marin County is a county located in the northwestern part of the San Francisco Bay Area of the U.S. state of California. As of the 2020 census, the population was 262,231. Its county seat and largest city is San Rafael. Marin County is acros ...
in 2016. * In 2013, a 107-year-old man from Pine Bluff, Arkansas, Monroe Isadore, died in a shootout with
SWAT In the United States, a SWAT team (special weapons and tactics, originally special weapons assault team) is a police tactical unit that uses specialized or military equipment and tactics. Although they were first created in the 1960s to ...
. * The last native speaker of Livonian,
Grizelda Kristiņa The Livonian language ( liv, līvõ kēļ, link=no or ; et, liivi keel, link=yes) is a Finnic language whose native land is the Livonian Coast of the Gulf of Livonia, located in the north of the Kurzeme peninsula in Latvia. Although its last n ...
, died in 2013 in
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
at the age of 103. * 101-year-old Nepalese man Funchu Tamang was rescued from the April 2015 Nepal earthquake. * In May 2015 Marjorie "Bo" Gilbert, from
South Wales South Wales ( cy, De Cymru) is a loosely defined region of Wales bordered by England to the east and mid Wales to the north. Generally considered to include the historic counties of Glamorgan and Monmouthshire, south Wales extends westwards ...
, became the first centenarian to appear in the magazine ''
Vogue Vogue may refer to: Business * ''Vogue'' (magazine), a US fashion magazine ** British ''Vogue'', a British fashion magazine ** ''Vogue Arabia'', an Arab fashion magazine ** ''Vogue Australia'', an Australian fashion magazine ** ''Vogue China'', ...
'', when she was featured as part of an advertisement for the department store
Harvey Nichols Harvey Nichols is a British luxury department store chain founded in 1831, at its flagship store in Knightsbridge, London. It sells designer fashion collections for men and women, fashion accessories, beauty products, fine wines and luxury f ...
.


Famous centenarians in media


Athletes

*In 2015,
Hidekichi Miyazaki Hidekichi Miyazaki (September 22, 1910 – January 23, 2019) was a Japanese centenarian masters athlete in sprinting, affectionally nicknamed Golden Bolt, a name play on former Jamaican sprinter Usain Bolt. He was a former official holder of the ...
, a Japanese masters athlete affectionately nicknamed ''Golden Bolt'' (a word-play on athlete
Usain Bolt Usain St. Leo Bolt, , (; born 21 August 1986) is a retired Jamaican sprinter, widely considered to be the greatest sprinter of all time. He is the world record holder in the 100 metres, 200 metres, and 4 × 100 metres relay. An eight- ...
) became the world's oldest sprinter to complete the 100m aged 105 and was certified by
Guinness World Records ''Guinness World Records'', known from its inception in 1955 until 1999 as ''The Guinness Book of Records'' and in previous United States editions as ''The Guinness Book of World Records'', is a reference book published annually, listing world ...
. * In 2015, Mieko Nagaoka, a 100-year-old Japanese woman, became the first centenarian to complete a 1500m swim in a 25-meter pool; specifically, she completed 30 laps in the pool in 1 hour, 15 minutes, 54 seconds. * On 30 April 2016, Ida Keeling, a
track and field Track and field is a sport that includes athletic contests based on running, jumping, and throwing skills. The name is derived from where the sport takes place, a running track and a grass field for the throwing and some of the jumping events ...
athlete, became the first woman in history to complete a 100-meter run aged 100. Her time of 1:17.33 was witnessed by a crowd of 44,469 at the 2016 Penn Relays. * In 2017, Julia Hawkins (age 101) became the oldest woman ever in the USA Track and Field Outdoors Masters Championships, and ran the 100 meters in 40.12 seconds. Previously that year she had run the 100 meters in 39.62 seconds. That is a new world record for women 100 or older.


See also

*
Food choice of older adults Food preferences in older adults and seniors take into consideration how people's dietary experiences change with aging, and help people understand how taste, nutrition, and food choices can change throughout one's lifetime. This can occur when p ...
*
Life extension Life extension is the concept of extending the human life expectancy, lifespan, either modestly through improvements in medicine or dramatically by increasing the maximum lifespan beyond its generally-settled oldest people, limit of 125 years. S ...
* Lists of centenarians *
New England Centenarian Study The New England Centenarian Study is a study of persons aged 100 and over (centenarians) in the Boston area. The study began in 1994 and was originally focused on research into Alzheimer's. However, it soon became apparent that most centenarians d ...
*
Okinawa Centenarian Study The Okinawa Centenarian Study is a study of the elderly people of Okinawa, Japan. The study, funded by Japan's ministry of health, is the largest of its kind ever carried out. Over the years, the scientists involved have had access to more than 6 ...
* Oldest people *
Queensland Community Care Network Queensland Community Care Network Inc. (QCCN) is a charity organisation based in Queensland, Australia. QCCN was established in June 1990 to provide broad-based community services directly to people requiring some level of community or home supp ...
, which operates the centenarians-only 100+ club


References


Further reading

*


External links


New England Centenarian Study

Okinawa Centenarian Study

Mortality of Centenarians
via Princeton University (archived 16 February 2006)

via Political Graveyard (archived 11 January 2009)
Noted Nonagenarians and Centenarians
via Genarians.com
Centenarian research and celebration
via AdlerCentenarians.org
Living Beyond 100
via International Longevity Center UK (archived 16 June 2017)

via Demogr.mpg.de

(archived 24 June 2007)
Oldest People in Britain
{{Authority control *Centenarians Senescence