Zosurabalpin (RG6006, Abx-MCP, Ro7223280) is an experimental
antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...
developed in a collaboration between the pharmaceutical company
Roche and scientists from
Harvard University, for the treatment of
carbapenem-resistant ''
Acinetobacter baumannii'' (CRAB). It targets a
lipopolysaccharide transporter.
It works by recognizing a composite binding site made up of both the Lpt transporter and its LPS substrate. The chemical family to which it belongs was first disclosed in 2019, but the particular structure of RG6006 remained confidential until publication of the testing results in 2023.
See also
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Clovibactin
Clovibactin (Novo29) is an experimental antibiotic isolated from an uncultured soil Gram-negative β-proteobacterium ''Eleftheria terrae'' ssp. ''carolina'', which is one of many soil bacteria
Soil microbiology is the study of microorganisms ...
*
Novobiocin
Novobiocin, also known as albamycin or cathomycin, is an aminocoumarin antibiotic that is produced by the actinomycete '' Streptomyces niveus'', which has recently been identified as a subjective synonym for ''S. spheroides'' a member of the clas ...
*
Teixobactin
References
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Antibiotics
Peptides
Heterocyclic compounds with 3 rings
Sulfur heterocycles
Biphenyls
Pyridines