The Zincke nitration is a nitration reaction in which a bromine is replaced by a

nitro Nitro may refer to: Chemistry *Nitrogen, a chemical element and a gas except at very low temperatures, with which many compounds are formed: **Nitro compound, an organic compound containing one or more nitro functional groups, -NO2 **Nitroalkene, ...

group on an electron-rich aryl compound such as a phenol or cresol. Typical reagents are nitrous acid or sodium nitrite. The reaction is a manifestation of nucleophilic aromatic substitution and is named after

Theodor Zincke Ernst Carl Theodor Zincke (19 May 1843 – 17 March 1928) was a German chemist and the academic adviser of Otto Hahn. Life Theodor Zincke was born in Uelzen on 19 May 1843. He became a pharmacist and graduated in Göttingen with his Staatsexame ...

, who first reported it in 1900. Two examples: and: The Zincke nitration should not be confused with the

Zincke–Suhl reaction The Zincke–Suhl reaction is a special case of a Friedel-Crafts alkylation and was first described by Theodor Zincke and Suhl in 1906.M Newman. ''A Study of the Zincke and Suhl Reaction'', ''J. Am. Chem. Soc.'' 19(6) (1954) p978M Newman. ''The Alu ...

or the

Zincke reaction The Zincke reaction is an organic reaction, named after Theodor Zincke, in which a pyridine is transformed into a pyridinium salt by reaction with 2,4-dinitro-chlorobenzene and a primary amine. The Zincke reaction should not be confused with th ...

References

{{Reflist Nitration reactions Substitution reactions Name reactions 1900 in science

See also

References