Zeda Fran Rosenberg is an American

microbiologist A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, f ...

and

epidemiologist Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and risk factor, determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decision ...

, active in

HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...

biology and prevention. She is the

chief executive officer A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially ...

of the

International Partnership for Microbicides The International Partnership for Microbicides or IPM is a non-profit product development partnership (PDP) founded by Dr. Zeda Rosenberg in 2002 to prevent HIV transmission by accelerating the development and availability of a safe and effective ...

(IPM). IPM was founded by Rosenberg in 2002 and is a

nonprofit organization A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in co ...

dedicated to developing

microbicides An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals ar ...

and other innovative HIV prevention products and making them available for women in

developing countries A developing country is a sovereign state with a lesser developed industrial base and a lower Human Development Index (HDI) relative to other countries. However, this definition is not universally agreed upon. There is also no clear agreem ...

. Rosenberg received her undergraduate degree (BA) in

biology Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary i ...

and

mathematics Mathematics is an area of knowledge that includes the topics of numbers, formulas and related structures, shapes and the spaces in which they are contained, and quantities and their changes. These topics are represented in modern mathematics ...

from Douglass College,

Rutgers University Rutgers University (; RU), officially Rutgers, The State University of New Jersey, is a Public university, public land-grant research university consisting of four campuses in New Jersey. Chartered in 1766, Rutgers was originally called Queen's ...

, and both her master's degree (SM) in

epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...

and her doctoral degree (ScD) in

microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, prot ...

from the

Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first ...

. Rosenberg is a champion for developing new

prevention products, women's empowerment and protecting women's health. Her opinions and commentary have been featured in a variety of international media, including

New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid d ...

The Globe and Mail ''The Globe and Mail'' is a Canadian newspaper printed in five cities in western and central Canada. With a weekly readership of approximately 2 million in 2015, it is Canada's most widely read newspaper on weekdays and Saturdays, although it ...

(Canada),

The Daily Nation The ''Daily Nation'' is the highest circulation Kenyan independent newspaper with 170,000 copies. History The ''Daily Nation'' was started in the year 1958 as a Swahili weekly called ''Taifa'' by the Englishman Charles Hayes. It was bought ...

(Kenya),

Nature News ''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It ...

and the

South African Medical Journal The ''South African Medical Journal'' is a monthly peer-reviewed open-access medical journal which has been published in South Africa since 1884. It is sponsored by the South African Medical Association and published by the association's publishin ...

. She has authored many scientific articles and has been a featured speaker at multiple high-level conferences and events, including the IAS Conference on HIV Pathogenesis, Treatment and Prevention, the

International AIDS Conference The International AIDS Society (IAS) is the world's largest association of HIV/AIDS professionals, with 11,600 members from over 170 countries , including clinicians, people living with HIV, service providers, policy makers and others. It aims to r ...

, Women Deliver, and the

United Nations General Assembly The United Nations General Assembly (UNGA or GA; french: link=no, Assemblée générale, AG) is one of the six principal organs of the United Nations (UN), serving as the main deliberative, policymaking, and representative organ of the UN. Curr ...

Special Session on HIV/AIDS.

Early career history

From 1999 to 2002, Rosenberg was the scientific director for the HIV Prevention Trials Network (HPTN) at

Family Health International FHI 360 (formerly Family Health International) is a nonprofit human development organization based in North Carolina. FHI 360 operates in more than 70 countries and all U.S. states and territories. Established in 1971, the organization manages ...

(FHI). In that role, she managed scientific and operational coordination of international clinical trials in the prevention of mother-to-child transmission of HIV, sexual transmission and transmission of HIV through intravenous drug use. From 1987 to 1999, Rosenberg worked in several capacities at the

National Institute of Allergy and Infectious Diseases The National Institute of Allergy and Infectious Diseases (NIAID, ) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's ...

(NIAID) at the U.S.

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

(NIH). She was senior scientist in the Division of AIDS from 1995 to 1999. In that capacity, she directed HIV prevention clinical trials, providing leadership, planning, implementation, administration and evaluation of a global program of extramural research on the prevention of HIV transmission in adult populations. Rosenberg was the assistant to the director and then assistant director for prevention research at NIAID from 1987 to 1995. In this position, she was responsible for all scientific research areas related to

AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...

, functioning as a liaison and facilitating scientific exchange between intramural research laboratories and the office of the director. She also coordinated the NIAID

Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...

(TB) Research effort, representing NIH on the Public Health Service Task Force to Combat Multi-Drug Resistant TB and co-chairing the TB Research Subcommittee. In addition, she was responsible for coordinating other Institute disease-prevention activities, including in the areas of HIV and other

sexually transmitted disease Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs) and the older term venereal diseases, are infections that are spread by sexual activity, especially vaginal intercourse, anal sex, and oral ...

At IPM

Rosenberg provides vision, leadership and direction to IPM, which has become a leading product development partnership in the HIV prevention field. Under Dr. Rosenberg's leadership, IPM has entered into six non-exclusive, royalty-free licenses with five major

pharmaceutical companies The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate symptoms. ...

—

Bristol-Myers Squibb The Bristol Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the lar ...

Gilead Sciences Gilead Sciences, Inc. () is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and CO ...

, Merck & Co.,

Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...

and Tibotec Pharmaceuticals (division of

Johnson & Johnson Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...

) — to develop, manufacture and distribute eight

antiretroviral The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multipl ...

(ARV) products as

. In 2011, IPM will initiate a Phase III clinical program to evaluate the dapivirine vaginal ring, an antiretroviral-based product that could potentially provide women with HIV protection for a month or longer. The program will involve up to 6,000 women in many communities throughout sub-Saharan Africa, where the HIV/AIDS epidemic has hit hardest.

Professional affiliations

International AIDS Society The International AIDS Society (IAS) is the world's largest association of HIV/AIDS professionals, with 11,600 members from over 170 countries , including clinicians, people living with HIV, service providers, policy makers and others. It aims to r ...

(IAS), 2004-current *

Global Health Council The Global Health Council is a United States-based non-profit leading networking organization "supporting and connecting advocates, implementers and stakeholders around global health priorities worldwide". The Council is the world's largest membe ...

, 2002-current * Global HIV Prevention Working Group, 2002-current * IAS Industry Liaison Forum, 2004-current

Publications

# Haseltine, W.A., Pederson, F.S., Sahagan, B.G., Rosenberg, Z.F., and Koslov, J. Comparative analysis of RNA tumor virus genomes. In: R. Neth and R. Gallo, eds., Modern Trends in Human Leukemia III, pps. 529–552, Springer-Verlag, Berlin (1979) # Rosenberg, Z.F., and Haseltine, W.A. A transfection assay for transformation by feline sarcoma virus proviral DNA. Virology 102: 240-244 (1980). # Rosenberg, Z.F., Pederson, F.S. and Haseltine, W.A. Comparative analysis of the genomes of feline leukemia viruses. J. Virol. 35: 542-546 (1980). # Rosenberg, Z.F., Snyder, H.W., Jr., and Haseltine, W.A. Characterization of murine cells transformed by feline sarcoma virus (FeSV) proviral DNA. In: W. Hardy, Jr., M. Essex, and A.J. McClelland, eds., Feline Leukemia Virus, Elsevier North-Holland Inc., NY, pps. 335-344 (1980). # Rosenberg, Z.F., Pederson, F.S. and Haseltine, W.A. Comparative analysis of the genomes of feline leukemia viruses. In: W. Hardy, Jr., M. Essex, and A.J. McClelland, eds., Feline Leukemia Virus, Elsevier North-Holland Inc., NY, pps. 355-359 (1980). # Sahagan, B.G., Rosenberg, Z.F., and Haseltine, W.A. Restriction enzyme analysis of the feline sarcoma virus provirus in murine fibroblasts transformed by transfection. In: W. Hardy, Jr., M. Essex, and A.J. McClelland, eds., Feline Leukemia Virus, Elsevier North-Holland Inc., NY, pps 345-352 (1980). # Rosenberg, Z.F., Sahagan, B.G., Snyder, H.W., Jr., Worley, M.B., Essex, M., and Haseltine, W.A. Biochemical characterization of cells transformed via transfection by feline sarcoma virus proviral DNA. J. Virol. 38: 782-788 (1981). # Rosenberg, Z.F., Sahagan, B.G., Worley, M.B., Essex, M., and Haseltine, W.A. Transformation with subgenomic fragments of feline sarcoma virus proviral DNA. Virology 112: 496-504 (1981). # Rosenberg, Z.F., Crowther, R.L., Essex, M., Jarrett, O. and Haseltine, W.A. Isolation via transfection of feline leukemia viruses from DNA of mediastinal tumors. Virology 115: 203-210 (1981). # Koenig, S. and Rosenberg, Z.F. Immunology of infection with the human immunodeficiency virus (HIV): A view from the III International Conference on AIDS. Ann. Intern. Med. 107: 409-412 (1987). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenesis of human immunodeficiency virus infection. Clin. Immunol. News. 9: 1-4 (1988). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infections. Ann. N.Y. Acad. Sci. 546:164- 174 (1988). # Rosenberg, Z.F. and Fauci, A.S. Update of HIV vaccine trials at the National Institutes of Health. In: M. Girard and L. Valette, eds., Proceedings of the Third Cent Gardes Symposium, Pasteur Vaccine, Marnes-La-Coquette, France, pps.287-292 (1988). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenic mechanism of HIV infection. Clin. Immunol. Immunopathol. 50: S149-S156 (1989). # Rosenberg, Z.F. and Fauci, A.S. Induction of expression of HIV in latently or chronically infected cells. AIDS Res. Hum. Retroviruses 5:1-4 (1989). # Rosenberg, Z.F. and Fauci, A.S. The immunopathogenesis of HIV infection. Adv. Immunol. 47:377-431 (1989). # Rosenberg, Z.F. and Fauci, A.S. Immunology of AIDS: Approaches to understanding the immunopathogenesis of HIV infection. La Ricerca 19:189-209 (1989). # Fauci, A.S. and Rosenberg, Z.F. Immunopathogenic mechanisms of HIV infection. In: F. Melchers et al., eds., Progress in Immunology VII, Springer-Verlag, Berlin, pps. 1028-1035 (1989). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenic Mechanisms of HIV Infection: Cytokine induction of HIV expression. Immunol. Today 11:176-180 (1990). # Rosenberg, Z.F. and Fauci, A.S. Immunopathology and pathogenesis of HIV infection. In: P. Pizzo and C. Wilfert, eds., Pediatric AIDS: The Challenge of HIV Infection in Infants, Children, and Adolescents. Williams and Wilkins, Baltimore, MD, pp. 82–94, (1990). # Rosenberg, Z.F. and Fauci, A.S. Inside the AIDS Virus. New Scientist 1703:51-54 (1990). # Rosenberg, Z.F. and Fauci A.S. Activation of latent HIV infection. J. NIH Res. 2:41-45 (1990). # Fauci, A.S. and Rosenberg, Z.F. Human Retroviruses. In: S. Baron and P.M. Jennings, eds., Medical Microbiology, Churchill Livingstone Inc., New York, pps. 801-816 (1991). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenic mechanisms of HIV infection. In: R.C. Gallo and G. Jay, eds., The Human Retroviruses, Academic Press, Inc., Orlando, Fla., pps. 141–162, (1991). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenesis of HIV infection. FASEB J. 5:2382-2390 (1991). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenesis of human immunodeficiency virus infection. In: W.C. Koff, F. Wong-Staal, and R.C. Kennedy, eds., AIDS Research Reviews, Vol. 1, Marcel Dekker, Inc., N.Y., pp. 65–80, (1991). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenesis of HIV infection. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg, eds., AIDS: Etiology, Diagnosis, Treatment and Prevention, 3rd ed., J. B. Lippincott Company, Philadelphia, pp. 61–76, (1992). # Rosenberg, Z.F. and Fauci, A.S. Immunopathogenesis of HIV infection. In: T. C. Quinn, ed., Advances in Host Defense Mechanisms (Sexually Transmitted Diseases), Vol. 8. Raven Press, N. Y., pp. 165–200, (1992). # Rosenberg, Z.F. The research agenda: NIH research portfolio. In: Tuberculosis in New York City, Proceedings of the Julia M. Jones Sixth Annual Preventive Medicine Day, New York Lung Association, November 5, 1992, New York, N.Y., pp 4–5, (1992). # Rosenberg, Z.F. and Fauci, A.S. Immunology of HIV infection. In: W.E. Paul, ed., Fundamental Immunology, Third Edition, Raven Press, New York, NY, pp. 1375–1397, (1993). # Rosenberg, Z.F. and Fauci, A.S. Immunopathology and pathogenesis of HIV infection. In: P. Pizzo and C. Wilfert, eds., Pediatric AIDS: The Challenge of HIV Infection in Infants, Children, and Adolescents (2nd edition). Williams and Wilkins, Baltimore, MD, pp. 115–127, (1994). # Fauci, A.S. and Rosenberg, Z.F. Immunopathogenesis. In: S. Broder, T.C. Merigan, Jr., and D. Bolognesi, eds., Textbook of AIDS Medicine, Williams and Wilkins, Baltimore, MD, pp. 55–75, (1994). # Van Damme, L. and Rosenberg, Z.F. Microbicides and Barrier Methods in HIV Prevention. AIDS (13; Suppl A): S85-92; 1999. # Mayer, K.H., Peipert, J., Fleming, T., Fullem, A., Moench, T., Cu-Uvin, S., Bentley, M., Chesney, M., and Rosenberg, Z. Safety and Tolerability of Buffergel, a Novel Vaginal Microbicide, in Women in the United States. Clin. Infect. Dis. 32: 476–82; 2001. # Mauck, C., Rosenberg, Z., and Van Damme, L. Recommendations for the Clinical Development of Topical Microbicides: an Update. AIDS 15:857-868, 2001. # Cates, W., Jr., Rosenberg, Z., and Raymond, E. When Should the Public Be Informed of the Results of Medical Research?

etter Etter is a surname. Notable people with the surname include: *Albert Etter (born 1872), American horticulturist *Bill Etter (born 1950), American football quarterback *Bob Etter (born 1945), American football placekicker, bridge player, and profess ...

JAMA 286: 2944–45, 2001. # Rosenberg, Z. and Brown, G. Placing HIV Prevention in the Hands of Women: The Promise of Microbicides. SDI/UGF World Summit 2002. # Rosenberg, Z. A New Public-Private Partnership for Microbicides. Health and Sexuality 7: 15–17, 2002. # Mayer, K.H., Abdool Karim, S., Kelly, C., Maslankowski, L., Rees, H., Profy, A.T., Day, J., Welch, J., Rosenberg, Z., for the HIV Prevention Trials Network (HPTN) 020 Protocol Team. Safety and Tolerability of Vaginal PRO 2000 Gel in Sexually Active HIV-uninfected and Abstinent HIV-infected Women. AIDS 17: 321–329, 2003. # Harrison, P., Rosenberg, Z, and Bowcut, J. Topical Microbicides for Disease Prevention: Challenges and Opportunities for Scientific Collaboration. Clin Infect Dis 36: 1290–1294, 2003. # Coplan, P.M, Mitchnick, M, Rosenberg Z.F. Public Health: Regulatory Challenges in Microbicide Development. Science 304:1911-2, 2004. # Hoffman, I.F., Taha, T.E., Padian, N.S., Kelly, C.W., Welch, J.D., Martins.on, F.E., Kumwenda, N.I., Rosenberg, Z.F., Chilongozi, D.A., Brown J.M., Chirenje, M, Richardson, B.A. Nonoxynol-9 100 mg gel: multi-site safety study from sub-Saharan Africa. AIDS 18:2191-2195, 2004. # Tassiopoulos, K.K., Seage, G., Sam, N., Kiweli, I., Shao, J., Trong, T.H., Essex, M., Coplan, P., Rosenberg, Z., Hughes, M., Kapiga, S. Predictors of herpes simplex type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania. J Infect Dis 195: 493–501, 2007 # Kapiga, S.H., Sam N.E., Bang, H., Ni, Q, Ao, T.T., Kiwelu, I., Chiduo, S., Ndibe, U., Seage, G. 3rd, Coplan, P., Shao, J., Rosenberg, Z.F., Essex, M. The role of herpes simplex virus type 2 and other genital infections in the acquisition of HIV-1 among high-risk women in northern Tanzania. J Infect Dis 195:1260-1269, 2007 # Nuttall, J., Romano, J., Douville, K., Galbreath, C., Nel, A., Heyward, W., Mitchnick, M., Walker, S., Rosenberg, Z. The future of HIV prevention: prospects for an effective anti-HIV microbicide. Infect Dis Clin N Am 21: 219–239, 2007 # Nuttall, J., Douville, K., Galbreath, C., Walker, S., Norick, P., Rosenberg, Z. Challenges of producing a drug primarily for use in developing countries: microbicides for HIV prevention. Therapy 4: 725–730, 2007 # Cates, W. and Rosenberg, Z. Vaginal microbicides: What does the future hold? Contemp OBGYN pgs 22–28, April 15, 2008 # Romano J, Variano B, Coplan P, Van Roey J, Douville K, Rosenberg Z, Temmerman M, Verstraelen H, Van Bortel L, Weyers S, Mitchnick M. Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring. AIDS Res Hum Retro. 25: 483–488, 2009. # Nel A, Smythe S, Young K, Malcolm K, McCoy C, Rosenberg Z, Romano J. Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr. 51: 416–423, 2009.

References

{{DEFAULTSORT:Rosenberg, Zeda Living people American women epidemiologists American epidemiologists HIV/AIDS researchers Rutgers University alumni Harvard T.H. Chan School of Public Health alumni Year of birth missing (living people) 21st-century American women