Zaltoprofen (
JAN
Jan, JaN or JAN may refer to:
Acronyms
* Jackson, Mississippi (Amtrak station), US, Amtrak station code JAN
* Jackson-Evers International Airport, Mississippi, US, IATA code
* Jabhat al-Nusra (JaN), a Syrian militant group
* Japanese Article Num ...
; trade name Soleton) is a
nonsteroidal anti-inflammatory drug
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
(NSAID) used as an
analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
,
antipyretic, and
anti-inflammatory agent. It is a selective
COX-2 inhibitor and also inhibits
bradykinin
Bradykinin (BK) (Greek brady-, slow; -kinin, kīn(eîn) to move) is a peptide that promotes inflammation. It causes arterioles to dilate (enlarge) via the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor and ...
-induced pain responses without blocking
bradykinin receptors.
It was approved for use in Japan in 1993.
References
{{analgesic-stub
COX-2 inhibitors
Nonsteroidal anti-inflammatory drugs
Carboxylic acids