![Pre and post chemotherapy colorectal cancer](https://upload.wikimedia.org/wikipedia/commons/4/40/Pre_and_post_chemotherapy_colorectal_cancer.png)
CAPOX (also called XELOX) is a
chemotherapy regimen
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combinat ...
consisting of
capecitabine
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. For breast cancer it is often used together with docetaxel. It is taken by mouth.
Comm ...
(
trade name
A trade name, trading name, or business name, is a pseudonym used by companies that do not operate under their registered company name. The term for this type of alternative name is a "fictitious" business name. Registering the fictitious name w ...
Xeloda) combined with
oxaliplatin
Oxaliplatin, sold under the brand name Eloxatin among others, is a cancer medication (platinum-based antineoplastic class) used to treat colorectal cancer. It is given by injection into a vein.
Common side effects include numbness, feeling ti ...
.
Xelox regime operates in 3-week cycles, usually with 8 cycles in total; Xeloda is orally taken for twice daily for two weeks, while oxaliplatin is administrated by IV on the first day of the cycle; there is a one-week rest period before the next cycle.
Adverse effects
*
Neuropathy
Peripheral neuropathy, often shortened to neuropathy, is a general term describing disease affecting the peripheral nerves, meaning nerves beyond the brain and spinal cord. Damage to peripheral nerves may impair sensation, movement, gland, or o ...
*Diarrhea
References
Chemotherapy regimens used in colorectal cancer
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