XEFE may refer to:
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XEFE-TV, a television station serving the Laredo-Nuevo Laredo Metropolitan Area
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XEFE-AM
XEFE-AM (790 kHz) is a radio station in Nuevo Laredo, Tamaulipas
Nuevo Laredo () is a city in the Municipality of Nuevo Laredo in the Mexican state of Tamaulipas. The city lies on the banks of the Rio Grande, across from Laredo, United Sta ...
, a radio station serving the Laredo-Nuevo Laredo Metropolitan Area
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