Whitfield's ointment
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Whitfield's ointment is an acidic ointment used for the topical treatment of
dermatophytosis Dermatophytosis, also known as ringworm, is a fungal infection of the skin. Typically it results in a red, itchy, scaly, circular rash. Hair loss may occur in the area affected. Symptoms begin four to fourteen days after exposure. Multiple a ...
, such as
athlete's foot Athlete's foot, known medically as ''tinea pedis'', is a common skin infection of the feet caused by a fungus. Signs and symptoms often include itching, scaling, cracking and redness. In rare cases the skin may blister. Athlete's foot fungus ...
. It can have a slight burning effect that goes away after a few minutes. It is named after Arthur Whitfield (1868–1947), a British dermatologist. The original ointment contains 3%
salicylic acid Salicylic acid is an organic compound with the formula HOC6H4CO2H. A colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone, and has been listed by the EPA Toxic Substance ...
and 6%
benzoic acid Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, wh ...
in a suitable base, such as
lanolin Lanolin (from Latin 'wool', and 'oil'), also called wool yolk, wool wax, or wool grease, is a wax secreted by the sebaceous glands of wool-bearing animals. Lanolin used by humans comes from domestic sheep breeds that are raised specifically fo ...
or
petrolatum Petroleum jelly, petrolatum, white petrolatum, soft paraffin, or multi-hydrocarbon, CAS number 8009-03-8, is a semi-solid mixture of hydrocarbons (with carbon numbers mainly higher than 25), originally promoted as a topical ointment for its he ...
. Alternatively, a short-chain
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
or
fatty alcohol Fatty alcohols (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4–6 carbons to as many as 22–26, derived from natural fats and oils. The precise chain length varies ...
can be used as the base. Whitfield's ointment is not advised for areas of thinner skin, such as the scrotum or the groin, and in such sites should only be used diluted to half-strength. A systematic review of the medical literature comparing treatments for ringworm and jock itch was generally critical of the quality of data available. It concluded that there was "insufficient evidence to determine if Whitfield's ointment, a widely used agent, is effective", implying that the studies were of poor quality and therefore effectiveness could not be determined.Individual studies support its use as a cost-effective treatment.


See also

* Castellani's paint *
Friar's Balsam Tincture of benzoin is a pungent solution of benzoin resin in ethanol. A similar preparation called Friar's Balsam or Compound Benzoin Tincture contains, in addition, Cape aloes or Barbados aloes and storax resin. Friar's balsam was invented by Jo ...


References

{{Antifungals Ointments Antifungals for dermatologic use