What Have I Done to Deserve This? may refer to:
*
''What Have I Done to Deserve This?'' (film), a 1984 film by Pedro Almodóvar
*
"What Have I Done to Deserve This?" (song), a song by Pet Shop Boys and Dusty Springfield
*
"What Have I Done to Deserve This?" (''Grey's Anatomy''), an episode of the TV series ''Grey's Anatomy''
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