Windber Research Institute (WRI), now known as the Chan Soon-Shiong Institute of Molecular Medicine at Windber, is a

private Private or privates may refer to: Music * " In Private", by Dusty Springfield from the 1990 album ''Reputation'' * Private (band), a Denmark-based band * "Private" (Ryōko Hirosue song), from the 1999 album ''Private'', written and also recorde ...

non-profit A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in co ...

biomedical Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)

research institute that is focused on

women A woman is an adult female human. Prior to adulthood, a female human is referred to as a girl (a female child or Adolescence, adolescent). The plural ''women'' is sometimes used in certain phrases such as "women's rights" to denote female hum ...

health Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organiza ...

cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...

and processes of

aging Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In ...

, is located on Somerset Avenue in

Windber Windber is a borough in Somerset County, Pennsylvania, Somerset County, Pennsylvania, United States, about south of Johnstown, Pennsylvania, Johnstown. It was at one time a place of industrial activities which included coal mining, lumbering, and ...

, Pennsylvania. It opened in 2001. The first president, one of the co-founders of the institute, was Mr Nicholas Jacobs. Dr Richard Somiari was a co-founder and the first Scientific Director, Chief Scientific Officer and Chief Operating Officer of Windber Research Institute

Description

The research of WRI is mainly divided into tissue banking, data warehousing of clinical,

molecular A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...

(

genomic Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...

and

proteomic Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...

) and imaging data and data analysis and interpretation along with the biomedical informatics team. Through an existing relationship with the

Walter Reed Army Medical Center The Walter Reed Army Medical Center (WRAMC)known as Walter Reed General Hospital (WRGH) until 1951was the U.S. Army's flagship medical center from 1909 to 2011. Located on in the District of Columbia, it served more than 150,000 active and ret ...

, in the Clinical Breast Care Program, WRI currently has greater than 14,000 highly annotated breast tissues, alone, with more than 500 data fields and single pathologist review on each patient, integrated with all the molecular and imaging data as well. Studies are ongoing regarding

tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...

heterogeneity Homogeneity and heterogeneity are concepts often used in the sciences and statistics relating to the uniformity of a substance or organism. A material or image that is homogeneous is uniform in composition or character (i.e. color, shape, siz ...

disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...

and patient

stratification Stratification may refer to: Mathematics * Stratification (mathematics), any consistent assignment of numbers to predicate symbols * Data stratification in statistics Earth sciences * Stable and unstable stratification * Stratification, or str ...

, environment and

lifestyle Lifestyle often refers to: * Lifestyle (sociology), the way a person lives * ''Otium'', ancient Roman concept of a lifestyle * Style of life (german: Lebensstil, link=no), dealing with the dynamics of personality Lifestyle may also refer to: Bus ...

risk factors,

ethnicity An ethnic group or an ethnicity is a grouping of people who identify with each other on the basis of shared attributes that distinguish them from other groups. Those attributes can include common sets of traditions, ancestry, language, history, ...

, and biomarker development, all with a focus on addressing existing clinical problems. In addition, WRI is examining the impact of lifestyle modification programs, using diet, stress management and exercise along with group support, to reduce

cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...

risk factors, control

obesity Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's we ...

and impact

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

. This is part of the Ornish Lifestyle Program that is offered at Windber. Its diagnostic capabilities include digital and film

mammography Mammography (also called mastography) is the process of using low-energy X-rays (usually around 30 kVp) to examine the human breast for diagnosis and screening. The goal of mammography is the early detection of breast cancer, typically through d ...

, 4-D ultrasound, 16-slice PET/CT and a 3T HD MRI which are integrated into the clinical data, molecular data and image repository. In 2015, the Windber Medical Center and the WRI entered into an agreement with the Chan Soon-Shiong Institute of Molecular Medicine (SSSIOMM), founded by Dr.

Patrick Soon-Shiong Patrick Soon-Shiong (born July 29, 1952) is a Chinese-South African transplant surgeon, billionaire businessman, bioscientist, and media proprietor. He is the inventor of the drug Abraxane, which became known for its efficacy against lung, brea ...

and his wife Michelle Chan, to create an integrated health care organization. The agreement included creating a precision cancer treatment and research institute.

References

External links

Official web site
{{Authority control Companies based in Somerset County, Pennsylvania Health care companies established in 2001 American companies established in 2001 2001 establishments in Pennsylvania Privately held companies based in Pennsylvania