William Kirk may refer to:
*William Arthur Kirk, American mathematician
*William Astor Kirk, (1922–2011), American civil rights activist and author
*William F. Kirk, (1877–1927), American baseball writer and poet
*Billy Kirk, rugby league footballer of the 1930s for England, and Warrington
*William Kirk (cricketer), (1866–1904), English cricketer
*William L. Kirk, (1932–2017), American air force officer
*William Umpleby Kirk, (1843–1928), photographer
*Bill Kirk (1934–2009), American baseball player
*William Kirk (MP), (1795–1870), Member of the UK Parliament for Newry
*William Kirke, MP for Clitheroe (UK Parliament constituency), Clitheroe
*Will Kirk, Furniture restorer The Repair Shop
{{hndis, Kirk, William