William J. Dreyer, Ph.D. (1928 – April 23, 2004) was a molecular immunologist and California Institute of Technology (Caltech) professor of biology from 1963 to 2004. He completed his Ph.D. in biochemistry at the University of Washington in 1956. Dreyer then went to work at the

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

as a National Polio Foundation postdoctoral and as a research scientist studying the genetic code. While at NIH, he invented machinery for automating biochemical analyses. In 1963, he was appointed professor in biology division of Caltech. He collaborated with J. Claude Bennett researching the genetic coding for protein structure, gene splicing and monoclonal antibodies. Dreyer developed the automated protein sequencer while he was consulting with the Spinco division of Beckman Instruments and patented it in 1977. Dreyer died of cancer in 2004. The automated protein sequencer made it possible to obtain sequence information from very small quantities of protein, which then allowed corresponding genes to be identified in DNA libraries. This technology jump-started the modern-day genetic revolution. It is part of Historical Collections of the

National Museum of Health and Medicine The National Museum of Health and Medicine (NMHM) is a museum in Silver Spring, Maryland, near Washington, DC. The museum was founded by U.S. Army Surgeon General William A. Hammond as the Army Medical Museum (AMM) in 1862; it became the NMHM in ...

in Washington, D.C.

References

1928 births 2004 deaths American immunologists California Institute of Technology faculty Reed College alumni University of Washington alumni {{US-scientist-stub