William Brooke O'Shaughnessy
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Sir William Brooke O'Shaughnessy (from 1861 as William O'Shaughnessy Brooke) MD FRS (October 1809, in
Limerick Limerick ( ; ga, Luimneach ) is a western city in Ireland situated within County Limerick. It is in the province of Munster and is located in the Mid-West which comprises part of the Southern Region. With a population of 94,192 at the 2016 ...
, Ireland – 8 January 1889, in Southsea, England) was an Irish physician famous for his wide-ranging scientific work in pharmacology, chemistry, and inventions related to
telegraphy Telegraphy is the long-distance transmission of messages where the sender uses symbolic codes, known to the recipient, rather than a physical exchange of an object bearing the message. Thus flag semaphore is a method of telegraphy, whereas ...
and its use in India. His medical research led to the development of intravenous therapy and introduced the therapeutic use of ''
Cannabis sativa ''Cannabis sativa'' is an annual herbaceous flowering plant indigenous to Eastern Asia, but now of cosmopolitan distribution due to widespread cultivation. It has been cultivated throughout recorded history, used as a source of industrial fibe ...
'' to Western medicine.


Early life

O'Shaughnessy was born at Limerick in 1809 to Daniel O'Shaughnessy and Sarah Boswell. His mother was a Protestant and many in the family were clergymen. An uncle of his was the Dean of Ennis and a great uncle the Roman Catholic Bishop of Killaloe. William studied briefly at Trinity College, Dublin matriculating in 1825 but moved to Scotland before graduating. O'Shaughnessy studied
forensic toxicology Forensic toxicology is the use of toxicology and disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. The primary concern for forensic toxicology is ...
and chemistry in Scotland, and graduated in 1829 with an MD from the
University of Edinburgh Medical School The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the University of Edinburgh College of Medicine and Veterinar ...
. In 1829 he was a clinical assistant of
William Alison William Pulteney Alison FRSE FRCPE FSA (12 November 1790 – 22 September 1859) was a Scottish physician, social reformer and philanthropist. He was a distinguished professor of medicine at the University of Edinburgh. He served as president ...
. In 1831, at the age of 22, as a result of his analysis of the blood of cholera victims, O'Shaughnessy laid the foundation, along with Thomas Aitchison Latta, for what was to become intravenous fluid and electrolyte-replacement therapy in the treatment of cholera. O'Shaughnessy analyzed the urine and blood of cholera patients and came to the conclusion that oxygen in the blood could reverse the actions. He found the blood deficient in water, salt, and "free alkali" and suggested that injecting salts would help. The method used by O'Shaughnessy on a dog and was developed further by Latta. Mikuriya, Tod H., MD, Marijuana Medical Papers, 1839-1972 O'Shaughnessy failed to obtain a position Professor of Medical Jurisprudence in the University of London and his first marriage forced him to join the service of the
British East India Company The East India Company (EIC) was an English, and later British, joint-stock company founded in 1600 and dissolved in 1874. It was formed to trade in the Indian Ocean region, initially with the East Indies (the Indian subcontinent and South ...
on 8 August 1833 and he moved to
Calcutta Kolkata (, or , ; also known as Calcutta , List of renamed places in India#West Bengal, the official name until 2001) is the Capital city, capital of the Indian States and union territories of India, state of West Bengal, on the eastern ba ...
, remaining in
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
and serving initially at Gyah and Cuttack before joining the 72nd Bengal Native Infantry. He joined the 10th Regiment Bengal Light Cavalry in 1835 and was an assistant to the Opium Agent in Bihar till 5 August 1835 when he became Professor of the medical college in Calcutta. He served on the committee of the Materia Medica until 1840 and later was Chemical Examiner to the government. As chemical examiner he developed methods for forensic studies for detecting arsenic poisoning as well as botanical toxins (such as from ''
Plumbago ''Plumbago'' is a genus of 10–20 species of flowering plants in the family Plumbaginaceae, native to warm temperate to tropical regions of the world. Common names include plumbago and leadwort (names which are also shared by the genus ''Cerato ...
'' used as an abortifacient). He went on furlough to England in 1841 to 1844 and returned to join as Chemical Examiner and additionally as Deputy Assay Master of the Calcutta Mint.


Work in India

His first stint in India was marked by work in the subjects of botanical pharmacology, chemistry, galvanic electricity, and underwater conduction, among others. He worked on modifications to the
Daniell cell The Daniell cell is a type of electrochemical cell invented in 1836 by John Frederic Daniell, a British chemist and meteorologist, and consists of a copper pot filled with a copper (II) sulfate solution, in which is immersed an unglazed earthenw ...
and the use of tanned leather semi-permeable membranes in them. He identified the use of zinc to reduce the rusting of iron before the process of galvanizing had been established. O'Shaughnessy also analyzed the gun-cotton developed by Christian Friedrich Schönbein and recognized the role of nitrogen and correctly identified the role of sulphuric acid in removing water from the cotton. He also developed a silver chloride electrode and experimented on adding colour tones to the Daguerre photographic process. At
Calcutta Kolkata (, or , ; also known as Calcutta , List of renamed places in India#West Bengal, the official name until 2001) is the Capital city, capital of the Indian States and union territories of India, state of West Bengal, on the eastern ba ...
, he was a member of the
Medical and Physical Society of Calcutta The ''Medical and Physical Society of Calcutta'' was a society of British officials, mostly physicians, formed on March 1, 1823. The society published a quarterly journal and met at the Asiatic Society. The journal published articles on diseases pr ...
, where he published one of his first papers on medical applications of
cannabis ''Cannabis'' () is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: '' Cannabis sativa'', '' C. indica'', and '' C. ruderalis''. Alternative ...
. He validated folk uses of cannabis in India, discovered new applications, and ultimately recommended cannabis for a great variety of therapeutic purposes. O'Shaughnessy established his reputation by successfully relieving the pain of rheumatism and stilling the convulsions of an infant with cannabis. He eventually popularized its use back in England. His most famous success came when he quelled the wrenching muscle spasm of tetanus and rabies with resin. While he could not cure tetanus, he observed that the cannabis mixture reduced their symptoms of
spasticity Spasticity () is a feature of altered skeletal muscle performance with a combination of paralysis, increased tendon reflex activity, and hypertonia. It is also colloquially referred to as an unusual "tightness", stiffness, or "pull" of muscles ...
and their suffering. In 1837 he published his independent design of an electric motor. In 1839, O'Shaughnessy conducted experiments on an experimental telegraphy system that he set up in the Botanical Garden at Calcutta with the assistance of Nathaniel Wallich. A length of 22 miles of wire was laid by zigzagging them over bamboo posts. In 1841, he returned to England, where he introduced ''
Cannabis indica ''Cannabis indica'' is an annual plant species in the family Cannabaceae which produces large amounts of tetrahydrocannabinol (THC) and is cultivated for purposes including hashish in India. The high concentrations of THC provide euphoric effec ...
'' to Western medicine and continued his scientific writings. He was a member of the
London Electrical Society The London Electrical Society was established in 1837 to enable amateur electricians to meet and share their interests in “experimental investigation of Electrical Science in all its various branches”. Although it initially flourished the societ ...
and was elected a
fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathemat ...
on 16 March 1843. The Candidature for Election to Fellow of the Royal Society stated that he was "distinguished for his acquaintance with the science of Medicine and Chemistry, eminent as a Physician and as a promoter of education among the natives of Bengal". O'Shaughnessy was a supporter of the idea of education in native languages in medicine. He also wanted locally available sources of medicine to be utilized to provide inexpensive aid. As a teacher, he took students on field trips to the Botanical Garden to introduce them to the local medicinal plants. In 1837 he prepared a ''Manual of Chemistry'' of which a thousand copies were printed for use in Calcutta. A second edition was produced in 1842. Another major book was the ''Bengal Dispensatory and Pharmacopeia'' which included an appendix on the "improvement of Bengal pottery" (1840) since earthenware imports from Europe were proving to be expensive. The ''Bengal Dispensatory'' included descriptions of several plant species that were made or overseen by Wallich including those of ''Abelmoschus longifolius'', ''Pharbitis caerulea'', ''Hebradendron pictorium'' and ''Garcinia pictoria''. These descriptions have often been overlooked by botanists in the past.


Return to India

In 1844, O'Shaughnessy returned to India, where he worked in various government positions in the fields of pharmacology and assay.
Lord Dalhousie James Andrew Broun-Ramsay, 1st Marquess of Dalhousie (22 April 1812 – 19 December 1860), also known as Lord Dalhousie, styled Lord Ramsay until 1838 and known as The Earl of Dalhousie between 1838 and 1849, was a Scottish statesman and co ...
became interested in the establishment of a telegraphic network and he learnt of the work of O'Shaugnessy and found that he could work on the scheme. Dalhousie informed the Military Board that O'Shaugnessy was to work directly under Dalhousie's supervision and report directly without any other intermediary authorities. During this period he began work on various telegraph instruments and systems. After briefly returning to England in 1852, O'Shaughnessy was appointed Superintendent of Telegraphs in 1852. During the years 1853-5 3500 miles of telegraph were installed across India and he wrote numerous manuals and reports on his telegraph inventions. O'Shaughnessy was on leave in England during the mutiny year but in the same year Morse code was introduced into India and a message from Delhi to Punjab helped in moving troops in time. In 1858 a cable was laid in the Gulf of Mannar between India and Ceylon. O'Shaughnessy introduced a coil of fine wire in the circuit to protect the cables from lightning. His successor in the telegraphs department, Charles Adley, became a fierce critic of O'Shaughnessy's work.


Knighthood and return to England

In 1856 he was
knight A knight is a person granted an honorary title of knighthood by a head of state (including the Pope) or representative for service to the monarch, the church or the country, especially in a military capacity. Knighthood finds origins in the Gr ...
ed by
Queen Victoria Victoria (Alexandrina Victoria; 24 May 1819 – 22 January 1901) was Queen of the United Kingdom of Great Britain and Ireland from 20 June 1837 until her death in 1901. Her reign of 63 years and 216 days was longer than that of any previo ...
for his work on the telegraph in India. He was appointed Director-General of Telegraphs at this time. During the following years O'Shaughnessy wrote on telegraphy-related subjects, including a book of private codes for
encrypted In cryptography, encryption is the process of encoding information. This process converts the original representation of the information, known as plaintext, into an alternative form known as ciphertext. Ideally, only authorized parties can deci ...
telegraphy. In 1860, O'Shaughnessy returned to Europe for sick leave where he remained in obscurity until his death from senile asthenia at Southsea on 8 January 1889. He was buried at Highland Road Cemetery, Portsmouth. He adopted the surname Brooke by Royal Licence in 1861 on the death of a relative. He was married twice. His second wife was the daughter of Francis O'Shaughnessy and his third was Julia Greenly, daughter of Captain Sabine.


References


External links


The Life & Work of Sir William O'Shaughnessy Brooke

W. B. O’Shaughnessy and the Introduction of Cannabis to Modern Western Medicine
* {{DEFAULTSORT:Oshaughnessy, William Brooke 1808 births 1889 deaths Irish people of Scottish descent Cannabis researchers People from Limerick (city) Alumni of the University of Edinburgh British East India Company Army officers Fellows of the Royal Society Irish expatriates in India Medical College and Hospital, Kolkata British forensic scientists 19th-century Irish medical doctors Irish cannabis activists Irish healthcare managers 19th-century Irish businesspeople Scientists from County Limerick Medical doctors from County Limerick