Willem Einthoven (21 May 1860 – 29 September 1927) was a

Dutch Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People E ...

doctor Doctor or The Doctor may refer to: Personal titles * Doctor (title), the holder of an accredited academic degree * A medical practitioner, including: ** Physician ** Surgeon ** Dentist ** Veterinary physician ** Optometrist *Other roles ** ...

and

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...

. He invented the first practical electrocardiograph (ECG or EKG) in 1895 and received the

Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...

in 1924 for it ("for the discovery of the mechanism of the electrocardiogram"). original URL now redirects to https://ethw.org/Willem_Einthoven

Background

Willem Einthoven was born in

Semarang Semarang ( jv, ꦏꦸꦛꦯꦼꦩꦫꦁ , Pegon: سماراڠ) is the capital and largest city of Central Java province in Indonesia. It was a major port during the Dutch colonial era, and is still an important regional center and port today. ...

Java Java (; id, Jawa, ; jv, ꦗꦮ; su, ) is one of the Greater Sunda Islands in Indonesia. It is bordered by the Indian Ocean to the south and the Java Sea to the north. With a population of 151.6 million people, Java is the world's List ...

in the

Dutch East Indies The Dutch East Indies, also known as the Netherlands East Indies ( nl, Nederlands(ch)-Indië; ), was a Dutch colony consisting of what is now Indonesia. It was formed from the nationalised trading posts of the Dutch East India Company, which ...

(now

Indonesia Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania between the Indian and Pacific oceans. It consists of over 17,000 islands, including Sumatra, Java, Sulawesi, and parts of Borneo and New Guine ...

), the son of Louise Marie Mathilde Caroline de Vogel and Jacob Einthoven. His father, a doctor, died when Willem was a child. His mother returned to the

Netherlands ) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherl ...

with her children in 1870 and settled in

Utrecht Utrecht ( , , ) is the List of cities in the Netherlands by province, fourth-largest city and a List of municipalities of the Netherlands, municipality of the Netherlands, capital and most populous city of the Provinces of the Netherlands, pro ...

. His father was of Jewish and

descent, and his mother's ancestry was Dutch and

Swiss Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri * Swiss, North Carolina *Swiss, West Virginia * Swiss, Wisconsin Other uses *Swiss-system tournament, in various games and sports *Swiss Internation ...

. In 1885, Einthoven received a medical degree from the

University of Utrecht Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollme ...

. He became a professor at the

University of Leiden Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William, Prince of Orange, as a reward to the city of Le ...

in 1886. He married his first cousin Frédérique Jeanne Louise de Vogel (7 September 1861 31 January 1937) and supported her brother

Willem Willem () is a Dutch and West FrisianRienk de Haan, ''Fryske Foarnammen'', Leeuwarden, 2002 (Friese Pers Boekerij), , p. 158. masculine given name. The name is Germanic, and can be seen as the Dutch equivalent of the name William in English, Gui ...

through school at Leiden. In 1902, he became a member of the

Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...

. He died in

Leiden Leiden (; in English and archaic Dutch also Leyden) is a city and municipality in the province of South Holland, Netherlands. The municipality of Leiden has a population of 119,713, but the city forms one densely connected agglomeration wit ...

in the

and is buried in the graveyard of the Reformed "Green Church" () at 6 Haarlemmerstraatweg in

Oegstgeest Oegstgeest () is a town and municipality in the province of South Holland in the western Netherlands. Its population was in . Etymology The portion ''geest'' in the name refers to the geest lands, which were excavated in the seventeenth cent ...

. It is encouraged to visit his grave and pay respects.

Work

Before Einthoven's time, it was known that the beating of the heart produced electrical currents, but the instruments of the time could not accurately measure this phenomenon without placing electrodes directly on the heart. Beginning in 1901, Einthoven completed a series of prototypes of a

string galvanometer A string galvanometer is a sensitive fast-responding measuring instrument that uses a single fine filament of wire suspended in a strong magnetic field to measure small currents. In use, a strong light source is used to illuminate the fine filament ...

. This device used a very thin filament of conductive wire passing between very strong

electromagnet An electromagnet is a type of magnet in which the magnetic field is produced by an electric current. Electromagnets usually consist of wire wound into a coil. A current through the wire creates a magnetic field which is concentrated in the ...

s. When a current passed through the filament, the

magnetic field A magnetic field is a vector field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular to its own velocity and to ...

created by the current would cause the string to move. A light shining on the string would cast a shadow on a moving roll of photographic paper, thus forming a continuous curve showing the movement of the string. The original machine required water cooling for the powerful electromagnets, required five people to operate it and weighed some 270 kilograms. This device increased the sensitivity of the standard

galvanometer A galvanometer is an electromechanical measuring instrument for electric current. Early galvanometers were uncalibrated, but improved versions, called ammeters, were calibrated and could measure the flow of current more precisely. A galvanom ...

so that the electrical activity of the heart could be measured despite the insulation of flesh and bones. This invention allowed transthoracic electrocardiography. Willem Einthoven ECG

Although later technological advances brought about better and more portable EKG devices, much of the terminology used in describing an EKG originated with Einthoven. His assignment of the letters P, Q, R, S and T to the various deflections are still used. The term

Einthoven's triangle Einthoven's triangle is an imaginary formation of three limb leads in a triangle used in electrocardiography, formed by the two shoulders and the pubis. The shape forms an inverted equilateral triangle with the heart at the center. It is named aft ...

is named after him. It refers to the imaginary inverted

equilateral triangle In geometry, an equilateral triangle is a triangle in which all three sides have the same length. In the familiar Euclidean geometry, an equilateral triangle is also equiangular; that is, all three internal angles are also congruent to each othe ...

centered on the chest and the points being the standard

leads Lead is a chemical element with symbol Pb and atomic number 82. Lead or The Lead may also refer to: Animal handling * Leash, or lead * Lead (leg), the leg that advances most in a quadruped's cantering or galloping stride * Lead (tack), a lin ...

on the arms and leg. After his development of the string galvanometer, Einthoven went on to describe the electrocardiographic features of a number of

cardiovascular disorders Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, hea ...

. Later in life, Einthoven turned his attention to the study of

acoustics Acoustics is a branch of physics that deals with the study of mechanical waves in gases, liquids, and solids including topics such as vibration, sound, ultrasound and infrasound. A scientist who works in the field of acoustics is an acoustician ...

, particularly heart sounds which he researched with Dr. P. Battaerd. In 1924, Einthoven was awarded the

for inventing the first practical system of electrocardiography used in medical diagnosis.

Legacy

On 21 May 2019, on Einthoven's 159th birthday, he was honored with a

Google Doodle A Google Doodle is a special, temporary alteration of the logo on Google's homepages intended to commemorate holidays, events, achievements, and notable historical figures. The first Google Doodle honored the 1998 edition of the long-running an ...

References

External links

*
Willem Einthoven’s 159th Birthday
– Google Doodle {{DEFAULTSORT:Einthoven, Willem 1860 births 1927 deaths Nobel laureates in Physiology or Medicine Dutch people of Jewish descent Dutch people of Swiss descent Dutch physiologists 19th-century Dutch inventors Dutch Nobel laureates Electrophysiologists Indonesian Nobel laureates Utrecht University alumni Foreign Members of the Royal Society Academic staff of Leiden University Medical educators Members of the Royal Netherlands Academy of Arts and Sciences People from Semarang Burials in South Holland

Background

Work

Legacy

References

Further reading

External links