When Breath Becomes Air
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''When Breath Becomes Air'' is a
non-fiction Nonfiction, or non-fiction, is any document or media content that attempts, in good faith, to provide information (and sometimes opinions) grounded only in facts and real life, rather than in imagination. Nonfiction is often associated with be ...
autobiographical An autobiography, sometimes informally called an autobio, is a self-written account of one's own life. It is a form of biography. Definition The word "autobiography" was first used deprecatingly by William Taylor in 1797 in the English peri ...
book written by American neurosurgeon
Paul Kalanithi Paul Sudhir Arul Kalanithi (April 1, 1977 – March 9, 2015) was an American neurosurgeon and writer. His book ''When Breath Becomes Air'' is a memoir about his life and illness with stage IV metastatic lung cancer. It was posthumously published ...
. It is a
memoir A memoir (; , ) is any nonfiction narrative writing based in the author's personal memories. The assertions made in the work are thus understood to be factual. While memoir has historically been defined as a subcategory of biography or autobi ...
about his life and battling stage IV
metastatic Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, ...
lung cancer Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from tran ...
. It was posthumously published by
Random House Random House is an American book publisher and the largest general-interest paperback publisher in the world. The company has several independently managed subsidiaries around the world. It is part of Penguin Random House, which is owned by Germ ...
on January 12, 2016. In his last year of neurosurgical residency at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
, Kalanithi experiences negative changes in his health. Rapid weight loss, and severe back and chest pains begin to raise concern for him and his wife, Lucy Kalanithi. Kalanithi worries that cancer might have caused his symptoms and his decline of health – unlikely for people in their thirties. However, when X-ray results in a routine medical check-up return normal, his
primary care physician A primary care physician (PCP) is a physician who provides both the first contact for a person with an undiagnosed health concern as well as continuing care of varied medical conditions, not limited by cause, organ system, or diagnosis. The term ...
and he attribute the symptoms to aging and work overload. Determined to finish the last months of his residency, he ignores whatever symptoms have not subsided. A few weeks later, the symptoms come back, stronger than before. Around this time, Kalanithi and his wife experience conflict in their relationship when Lucy feels that he is not communicating with her. Visiting friends in New York, Kalanithi is almost certain that he has cancer and says it out loud for the first time to his friend Mike. Returning home, upon landing in
San Francisco San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of Ca ...
, Kalanithi receives a call from his doctor telling him that his lungs "look blurry." When he arrives home with Lucy, both of them know what is happening. The next day, Kalanithi checks in to the hospital, and the room where he examined his patients, delivering good and bad news, becomes his own.


Background

Before writing ''When Breath Becomes Air'', Kalanithi was in residency in neurological surgery and a postdoctoral fellowship in neuroscience. In May 2013, Kalanithi was diagnosed with stage-4 non-small-cell EGFR-positive lung cancer. As Kalanithi underwent cancer treatment, he shared his reflections on illness and medicine, authoring essays in ''The New York Times'', ''The Paris Review'', and ''Stanford Medicine'', and participating in interviews for media outlets and public forums. He also began work on an autobiographical book of his experiences as a doctor and a patient facing a terminal illness. Kalanithi died in March 2015 at the age of 37. His memoir was published posthumously 10 months later. The book includes a foreword by
Abraham Verghese Abraham Verghese (born 1955) is an American physician, author, Professor for the Theory and Practice of Medicine at Stanford University Medical School and Senior Associate Chair of the Department of Internal Medicine. He is also the author of ...
and an epilogue by Kalanithi's widow, Lucy Goddard Kalanithi.


Paul Kalanithi

The author of the book, Paul Kalanithi, was born in
Bronxville, New York Bronxville is a village in Westchester County, New York, United States, located approximately north of Midtown Manhattan. It is part of the town of Eastchester. The village comprises one square mile (2.5 km2) of land in its entirety, a ...
on April 1, 1977. At the age of 10, his family moved to
Kingman, Arizona Kingman is a city in, and the county seat of, Mohave County, Arizona, United States. It is named after Lewis Kingman, an engineer for the Atlantic and Pacific Railroad. It is located southeast of Las Vegas, Nevada, and northwest of Arizona's ...
where he spent most of his youth. At the early age of 10, his mother gave him books to read in order to educate his young mind. Kalanithi attended
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
where he earned Bachelor and Master of Arts in English literature and Bachelor of Science in human biology. He attended Cambridge for history and philosophy of science and medicine where he obtained his Masters. After Cambridge, Kalanithi attended
Yale Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wor ...
for medical school where he met his future wife, Lucy Goddard. After graduating Yale, they got married and began their residencies in California. Kalanithi started his residency back at Stanford while his wife attended
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Francisco, ...
, San Francisco. Paul and Lucy have a daughter together.


Synopsis

Following the prospect of a better life, Kalanithi's father moves the family from
Bronxville, New York Bronxville is a village in Westchester County, New York, United States, located approximately north of Midtown Manhattan. It is part of the town of Eastchester. The village comprises one square mile (2.5 km2) of land in its entirety, a ...
to
Kingman, Arizona Kingman is a city in, and the county seat of, Mohave County, Arizona, United States. It is named after Lewis Kingman, an engineer for the Atlantic and Pacific Railroad. It is located southeast of Las Vegas, Nevada, and northwest of Arizona's ...
when Kalanithi is ten. A doctor himself, Kalanithi's father dedicates most of his time to medicine and is notably absent from the house. Believing that to be a doctor, he would have to be away from the family like his father, Kalanithi becomes disenchanted with medicine. Although Kalanithi and his two brothers enjoy the newfound liberty of their desert town, their mother constantly worries for their academic future in a town that the U.S. census has declared “the least educated district in America.” Unwilling to let anything halt their learning, she acquires college reading lists and instills in her sons a love for literature. The summer before heading to
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
for school, Kalanithi reads '' Satan, His Psychotherapy and Cure by the Unfortunate Dr. Kassler, J.S.P.S.'', by
Jeremy Leven Jeremy Leven (born August 16, 1941) is an American screenwriter, director, producer, and novelist. Born in South Bend, Indiana, Leven lives in Woodbridge, Connecticut, Paris, and New York City. Early life Leven was educated at St. John's Colle ...
. The book's idea that the mind is the result of the brain doing its work awakes a curiosity in Kalanithi for neuroscience. After completing degrees in English literature and human biology, Kalanithi feels there is still much to learn. He is accepted to a master's program in English literature at Stanford, and one afternoon—pushed by his desire to understand the meaning of life— discovers the calling to practice medicine for the first time. Preparing to apply to medical school, Kalanithi uses the time off to study the history and philosophy of science and medicine at
Cambridge Cambridge ( ) is a university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cambridge bec ...
. He later starts medical school at
Yale Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wor ...
. During his time at Yale, Kalanithi meets his wife, Lucy, and sees the patient-doctor relationship as an example of life, death, and morality coming together. After two years of classroom learning, Kalanithi experiences his first birth and death in his OB-GYN clinical rotation, when a set of twins could not be carried to term. It is then that Kalanithi understands that intelligence is not enough in the practice of medicine, and that morality is also needed. After medical school, Lucy Kalanithi starts internal medicine residency at
UCSF The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It condu ...
and Paul Kalanithi begins a neurosurgical residency at Stanford. Though he finds it hard at first, Kalanithi grows used to the rigor of neurosurgery and, in his fourth year, joins the neuroscience lab of a professor affectionately called “V.” In the sixth year of residency, Kalanithi returns to his hospital duties and having reached professional recognition, he feels he has finally found his place in the world. Kalanithi's life takes an unexpected turn when, after weeks of health problems, it is confirmed that he has lung cancer. Images obtained from a CT scan show organ systems compromised by the cancer, causing him and his wife great sadness. Searching for the best experts in the field of oncology, Kalanithi begins treatment with a doctor named Emma Hayward. Because of his status, rather than stepping back and letting Hayward offer her professional opinion, Kalanithi expects to be treated as a consultant, even if it is his own case. Hayward suggests to find the root of his cancer before determining treatment options. In the meantime, Kalanithi's family helps him through his transition from doctor to patient and, together with Lucy, he decides to explore reproductive options before he dies. They visit a sperm bank and make the decision to have a child. Test results arrive and Kalanithi discovers that his cancer is derived from a mutation in the
epidermal growth factor receptor The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor recept ...
(EGFR). This fact gives him a bit of relief because it means that he can be treated with
Tarceva Erlotinib, sold under the brand name Tarceva among others, is a medication used to treat non-small cell lung cancer (NSCLC) and pancreatic cancer. Specifically it is used for NSCLC with mutations in the epidermal growth factor receptor (EGFR) ...
, which typically results in less-severe side effects compared to traditional chemotherapy. Symptoms subside with the treatment and, in Dr. Hayward's office, Kalanithi feels like himself again. After weeks of using the medication, CT scans show a reduced number of tumors in Kalanithi's lungs and he becomes determined to return to the operating room. Back in the OR, he cannot finish his first surgery because of his health. However, his strength and technique improve over time. With both graduation and a baby due in June, he takes another CT scan after months since the last. He discovers a big tumor in his right lung and without getting scared, he and Lucy research what other options are available. Kalanithi retires from surgery indefinitely and begins chemotherapy. His response to chemotherapy is adverse and his health worsens, forcing him to skip graduation. With the failure of chemotherapy, other treatment options do not provide him much hope. His condition becomes so severe that even Dr. Hayward gives an approximation of how much time he has left – something she had strongly refused to do before. On July 4, 2014, their daughter is born and Kalanithi is filled with joy. Eventually, Kalanithi dies in the intensive care unit of his hospital. The epilogue is written by his wife Lucy Kalanithi, after his death. It shows her point of view of the experience with her husband Paul Kalanithi's lung cancer. It is an in-depth personal explanation of her experience.


Reception

''When Breath Becomes Air'' is a ''New York Times'' bestseller, spending 68 weeks on the non-fiction bestseller list. The book was well-received by critics, included starred reviews from ''
Kirkus Reviews ''Kirkus Reviews'' (or ''Kirkus Media'') is an American book review magazine founded in 1933 by Virginia Kirkus (1893–1980). The magazine is headquartered in New York City. ''Kirkus Reviews'' confers the annual Kirkus Prize to authors of fic ...
'' and ''
Library Journal ''Library Journal'' is an American trade publication for librarians. It was founded in 1876 by Melvil Dewey. It reports news about the library world, emphasizing public libraries, and offers feature articles about aspects of professional prac ...
''. ''Kirkus'' called the book a "moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity." Matt McCarthy of ''
USA Today ''USA Today'' (stylized in all uppercase) is an American daily middle-market newspaper and news broadcasting company. Founded by Al Neuharth on September 15, 1982, the newspaper operates from Gannett's corporate headquarters in Tysons, Virgini ...
'' gave it 4 out of 4 stars and said, "It's a story so remarkable, so stunning, and so affecting that I had to take dozens of breaks just to compose myself enough to get through it." Nick Romeo of ''The Boston Globe'' wrote that it, "possesses the gravity and wisdom of an ancient Greek tragedy." Melissa Maerz of ''
Entertainment Weekly ''Entertainment Weekly'' (sometimes abbreviated as ''EW'') is an American digital-only entertainment magazine based in New York City, published by Dotdash Meredith, that covers film, television, music, Broadway theatre, books, and popular cul ...
'' stated that the book was "so original—and so devastating. . . . Its only fault is that the book, like his life, ends much too early."


Awards and honors


References


External links

* * * * {{cite web, title=When Breath Becomes Air: A Conversation About Life, Death, and Humanity in Health Care, date=June 24, 2018, publisher=The Aspen Institute, website=YouTube, url=https://www.youtube.com/watch?v=wi3aXaKr2TM 2016 non-fiction books Random House books American memoirs The Bodley Head books