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Warfield Theobald Longcope (29 March 187725 April 1953) was an American
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
. He served as physician-in-chief of the
Johns Hopkins Hospital The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 mo ...
and president of the
American Association of Immunologists The American Association of Immunologists (AAI) is an international scientific society dedicated to furthering the study of immunology. AAI provides its members with a variety of platforms in which to exchange ideas and present the latest immunolo ...
,
Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine." ...
, and
American Society for Clinical Investigation The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 ph ...
.


Early life and education

Warfield Longcope was born in
Baltimore, Maryland Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...
to George and Ruth (Theobald) Longcope. Tillett, William S.
"Warfield Theobald Longcope"
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
,
Washington, D.C. ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...
His mother's family had a long history of achievement in medicine, starting with Nathan Smith, the third graduate of Harvard College's medical department. Longcope graduated from
Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...
in 1897. In 1901 he graduated from the university's medical school, part of their fifth class of students."Memorial: Warfield Theobald Longcope, M.D."
Trans Am Clin Climatol Assoc. 1954; 65: liii–lvi.
Among the significant influences in his education were
William H. Welch William Henry Welch (April 8, 1850 – April 30, 1934) was an American physician, pathologist, bacteriologist, and medical-school administrator. He was one of the "Big Four" founding professors at the Johns Hopkins Hospital.William Osler Sir William Osler, 1st Baronet, (; July 12, 1849 – December 29, 1919) was a Canadian physician and one of the "Big Four" founding professors of Johns Hopkins Hospital. Osler created the first Residency (medicine), residency program for spec ...
. As a result of these influences, he elected to concentrate on pathology in his post-doctoral education."Portrait Collection: Warfield Theobald Longcope"
The Johns Hopkins Medical Institutions


Early medical career

After completing medical school, Longcope took a position as the resident pathologist at
Pennsylvania Hospital Pennsylvania Hospital is a private, non-profit, 515-bed teaching hospital located in Center City Philadelphia and is part of the University of Pennsylvania Health System. Founded on May 11, 1751, by Benjamin Franklin and Dr. Thomas Bond, Pennsylv ...
's Ayer Clinical Laboratory, working under the direction of
Simon Flexner Simon Flexner, M.D. (March 25, 1863 in Louisville, Kentucky – May 2, 1946) was a physician, scientist, administrator, and professor of experimental pathology at the University of Pennsylvania (1899–1903). He served as the first director of t ...
. By 1904, he was the laboratory director, a position he held until 1911. Between 1909 and 1911, he was also an assistant professor at the
University of Pennsylvania School of Medicine The Perelman School of Medicine, commonly known as Penn Med, is the medical school of the University of Pennsylvania, a private research university in Philadelphia, Pennsylvania. Founded in 1765, the Perelman School of Medicine is the oldest medi ...
. In 1911, he left to become an assistant professor at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
and physician at Presbyterian Hospital; by 1914, he was the medical director.


Wartime service

Longcope served in
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
as an
Army An army (from Old French ''armee'', itself derived from the Latin verb ''armāre'', meaning "to arm", and related to the Latin noun ''arma'', meaning "arms" or "weapons"), ground force or land force is a fighting force that fights primarily on ...
physician, his active duty service beginning in August 1917 and continuing through 1919. He was part of the Office of the Surgeon General of the Army, and later consulted for the
American Expeditionary Forces The American Expeditionary Forces (A. E. F.) was a formation of the United States Army on the Western Front of World War I. The A. E. F. was established on July 5, 1917, in France under the command of General John J. Pershing. It fought alon ...
.


Later career

At the end of his military service, Longcope returned to his positions at Columbia and Presbyterian. For a brief time in 1922, he was a professor at
Cornell University Medical School The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York (state), New York. Weill Cornell Medicine is af ...
, before returning to his alma mater later that year as director of the Johns Hopkins University medical department and physician-in-chief of Johns Hopkins Hospital."Warfield T. Longcope, M.D."
American Association of Immunologists
Longcope was one of the founding members of the American Society for Clinical Investigation,Brainard, Ellen R.
"History of the American Society for Clinical Investigation, 1909-1959"
J Clin Invest. 1959 Oct; 38(10 Pt 1-2): 1784–1837
and served as the organization's president in 1919. He was the president of the American Association of Immunologists from 1935-6, having already served as one of their councillors from 1934-5 (and again from 1936-1940). From 1945-6 he was president of the Association of American Physicians.


Awards and honors

During his long career, Longcope accumulated a number of awards. He was made a Fellow of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...
in 1923, was awarded the Bronze Medal of
American Roentgen Ray Society The American Roentgen Ray Society (ARRS) is the first and oldest radiology society in the United States. It was founded in 1900, in the early days of X-ray and radiation study. Headquartered in Leesburg, Virginia, the society publishes a monthly p ...
in 1937, became a member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
in 1943, and was awarded the Kober Medal in 1948.


Research interests

From the earliest phases of his medical education, Longcope had a particular interest in bacteriology and pathological anatomy. He spent much of his career studying antigen-antibody mechanisms. During his time with the military, he studied influenza and hemolytic streptococcus, both of which were major wartime concerns. He was one of the researchers on
Dimercaprol Dimercaprol, also called British anti-Lewisite (BAL), is a medication used to treat acute poisoning by arsenic, mercury, gold, and lead. It may also be used for antimony, thallium, or bismuth poisoning, although the evidence for those uses is not ...
("British Anti-Lewisite") during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
, and also encouraged its postwar civilian use as an antidote to metal poisoning. In total, he published 125 papers, including a major one after his retirement on
sarcoidosis Sarcoidosis (also known as ''Besnier-Boeck-Schaumann disease'') is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly af ...
. Longcope was noted for keeping files on his "favorite" diseases, with case notes, photographs, and other information for each; he kept these files current up through the final weeks of his life.


Family

Longcope married Janet Percy Dana in 1915. She was the daughter of
Paul Dana Paul Dana (; April 15, 1975 – March 26, 2006) was an American racing driver in the IndyCar Series. Early life Born in St. Louis, Missouri, Dana graduated from the Medill School of Journalism at Northwestern University. Before becoming a race ...
, editor of the
New York Sun ''The New York Sun'' is an American online newspaper published in Manhattan; from 2002 to 2008 it was a daily newspaper distributed in New York City. It debuted on April 16, 2002, adopting the name, motto, and masthead of the earlier New York ...
. They had four children, two boys and two girls. Continuing the family tradition, one of the sons became a physician as well. Christopher Longcope (1928–2003), one of Warfield Longcope's two sons, received his M.D. from Johns Hopkins Medical School and became a professor of medicine at the University of Massachusetts Medical School. (This obituary incorrectly attributes the founding of Dartmouth Medical School to Nathan R. Smith; the founder is Nathan Smith (1762–1829), who was Nathan R. Smith's father.) Warfield Longcope retired from active practice in 1946. He died of emphysema in 1953, at his farm in
Lee, Massachusetts Lee is a town in Berkshire County, Massachusetts, United States. It is part of the Pittsfield, Massachusetts, metropolitan statistical area. The population was 5,788 at the 2020 census. Lee, which includes the villages of South and East Lee, is p ...
.


References

{{DEFAULTSORT:Longcope, Warfield Theobald 1877 births 1953 deaths American pathologists American medical researchers Columbia University faculty Johns Hopkins University faculty Members of the United States National Academy of Sciences Johns Hopkins University alumni Cornell University faculty