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Walter Reed (September 13, 1851 – November 22, 1902) was a U.S. Army physician who in 1901 led the team that confirmed the theory of Cuban doctor Carlos Finlay that yellow fever is transmitted by a particular mosquito species rather than by direct contact. This insight gave impetus to the new fields of epidemiology and biomedicine, and most immediately allowed the resumption and completion of work on the Panama Canal (1904–1914) by the United States. Reed followed work started by Finlay and directed by
George Miller Sternberg Brigadier General George Miller Sternberg (June 8, 1838 – November 3, 1915) was a U.S. Army physician who is considered the first U.S. bacteriologist, having written ''Manual of Bacteriology'' (1892). After he survived typhoid and yellow fever, ...
, who has been called the "first U.S. bacteriologist".


Early and family life

Reed was born in Gloucester, Virginia, the fifth child of Lemuel Sutton Reed (a traveling Methodist minister) and his first wife, Pharaba White. During his youth, the family resided at Murfreesboro, North Carolina with his mother's family during his father's preaching tours. Two of his elder brothers later achieved distinction: J.C. became a minister in Virginia like their father, and Christopher a judge in Wichita, Kansas and later St. Louis, Missouri. Their childhood home is included in the
Murfreesboro Historic District Murfreesboro Historic District is a national historic district located at Murfreesboro, Hertford County, North Carolina. The district encompasses nine contributing buildings in the oldest section of the city of Murfreesboro. The buildings incl ...
. in December 1866, Rev. Reed remarried, to Mrs. Mary C. Byrd Kyle of
Harrisonburg, Virginia Harrisonburg is an independent city in the Shenandoah Valley region of the Commonwealth of Virginia in the United States. It is also the county seat of the surrounding Rockingham County, although the two are separate jurisdictions. At the 2 ...
, with whom he had a daughter. Young Walter enrolled at the University of Virginia. After two years, Reed completed the M.D. degree in 1869, two months before he turned 18. He was the youngest-ever recipient of an M.D. from the university. Reed then enrolled at the New York University's
Bellevue Hospital Medical College NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of ...
in Manhattan, New York City, where he obtained a second M.D. in 1870, as his brother Christopher attempted to set up a legal practice. After interning at several New York City hospitals, Reed worked for the New York Board of Health until 1875.


Personal life

He married Emily Blackwell Lawrence (1856–1950) of North Carolina on April 26, 1876, and took her West with him. Later, Emily gave birth to a son, Walter Lawrence Reed (1877–1956) and a daughter, Emily Lawrence Reed (1883–1964). While posted at frontier camps, the couple also adopted a Native American girl named Susie.


U.S. Army Medical Corps

Finding his youth limited his influence, and dissatisfied with urban life, Reed joined the
U.S. Army Medical Corps The Medical Corps (MC) of the U.S. Army is a staff corps (non-combat specialty branch) of the U.S. Army Medical Department (AMEDD) consisting of commissioned medical officers – physicians with either an M.D. or a D.O. degree, at least one ye ...
. This allowed him both professional opportunities and modest financial security to establish and support a family. After Reed passed a grueling thirty-hour examination in 1875, the army medical corps enlisted him as an assistant surgeon. By this time, two of his brothers were working in Kansas, and Walter soon was assigned postings in the American West. Over the next sixteen years, the Army assigned the career officer to different outposts, where he was responsible not only for American military and their dependents, but also various Native American tribes, at one point looking after several hundred
Apache The Apache () are a group of culturally related Native American tribes in the Southwestern United States, which include the Chiricahua, Jicarilla, Lipan, Mescalero, Mimbreño, Ndendahe (Bedonkohe or Mogollon and Nednhi or Carrizaleño an ...
s, including
Geronimo Geronimo ( apm, Goyaałé, , ; June 16, 1829 – February 17, 1909) was a prominent leader and medicine man from the Bedonkohe band of the Ndendahe Apache people. From 1850 to 1886, Geronimo joined with members of three other Central Apache ba ...
. Reed noticed the devastation epidemics could wreak and maintained his concerns about sanitary conditions. During one of his last tours, he completed advanced coursework in pathology and bacteriology in the Johns Hopkins University Hospital Pathology Laboratory. While stationed at Fort Robinson, Nebraska, Reed treated the ankle of Swiss immigrant Jules Sandoz, broken by a fall into a well. Reed wanted to amputate Sandoz's foot, but Sandoz refused his consent, and Reed succeeded in saving the foot by an extensive course of treatment. A photograph of a letter from Reed to Sandoz's father is reproduced in the first edition of ''Old Jules'', the 1935 biography of Sandoz by his daughter Mari Sandoz. In 1893, Reed joined the faculty of George Washington University School of Medicine & Health Sciences and the newly opened Army Medical School in Washington, D.C., where he held the professorship of Bacteriology and Clinical Microscopy. In addition to his teaching responsibilities, he actively pursued medical research projects and served as the curator of the Army Medical Museum, which later became the National Museum of Health and Medicine (NMHM). These positions also allowed Reed to break free from the fringes of the medical world. In 1896, Reed first distinguished himself as a medical investigator. He proved that yellow fever among enlisted men stationed near the Potomac River was not a result of drinking the river water. He showed officials that the enlisted men who got yellow fever had a habit of taking trails through the local swampy woods at night. Their fellow officers without yellow fever did not do so. Reed also proved that the local civilians drinking from the Potomac River had no relation to the incidence of the disease. Reed traveled to Cuba to study diseases in U.S. Army encampments there during the Spanish–American War. Appointed chairman of a panel formed in 1898 to investigate an epidemic of typhoid fever, Reed and his colleagues showed that contact with fecal matter and food or drink contaminated by flies caused that epidemic. Yellow fever also became a problem for the Army during this time, felling thousands of soldiers in Cuba. In May 1900, Major Reed returned to Cuba when he was appointed head of an investigative board charged by
Army Surgeon General The Surgeon General of the United States Army is the senior-most officer of the U.S. Army Medical Department (AMEDD). By policy, the Surgeon General (TSG) serves as Commanding General, U.S. Army Medical Command (MEDCOM) as well as head of the ...
George Miller Sternberg Brigadier General George Miller Sternberg (June 8, 1838 – November 3, 1915) was a U.S. Army physician who is considered the first U.S. bacteriologist, having written ''Manual of Bacteriology'' (1892). After he survived typhoid and yellow fever, ...
to study tropical diseases, particularly yellow fever. Sternberg was an early expert in bacteriology during a time of great advances due to widespread acceptance of the germ theory of disease and new methods for studying microbial infections. During Reed's leadership of the U.S. Army Yellow Fever Commission in Cuba, the Board demonstrated that yellow fever was transmitted by mosquitoes and disproved the common belief that it was transmitted by fomites (clothing and bedding soiled by the body fluids and excrement of yellow fever victims). These points were demonstrated in a dramatic series of experiments at the US Army's Camp Lazear, named in November 1900 for Reed's assistant and friend Jesse William Lazear, who had died of yellow fever while working on the project. This dangerous research was done using human volunteers, including some of the medical personnel, who allowed themselves to be bitten by mosquitos infected with yellow fever. The conclusions from this research were soon applied in Panama, where mosquito eradication was largely responsible for stemming the incidence of yellow fever during the construction of the Panama Canal. Epidemics of yellow fever in Panama had confounded French attempts to build a canal across the
Isthmus of Panama The Isthmus of Panama ( es, Istmo de Panamá), also historically known as the Isthmus of Darien (), is the narrow strip of land that lies between the Caribbean Sea and the Pacific Ocean, linking North and South America. It contains the country ...
only 20 years earlier. Although Reed received much of the credit for "beating" yellow fever, Reed himself credited Cuban medical scientist Carlos Finlay with identifying a mosquito as the vector of yellow fever and proposing how the disease might be controlled. Reed often cited Finlay in his own articles and gave him credit for the idea in his personal correspondence. The Cuban physician was a persistent advocate of the hypothesis that mosquitos were the vector of yellow fever and correctly identified the species that transmits the disease. His experiments to prove the hypothesis were discounted by many medical experts, but served as the basis for Reed's research. More recently, the politics and ethics of using medical and military personnel as research subjects have been questioned. Reed returned from Cuba in 1901, continuing to speak and publish on the topic of yellow fever. In recognition of his research, Reed received honorary degrees from Harvard and the University of Michigan. In November 1902, Reed suffered a ruptured
appendix Appendix, or its plural form appendices, may refer to: __NOTOC__ In documents * Addendum, an addition made to a document by its author after its initial printing or publication * Bibliography, a systematic list of books and other works * Index (pub ...
. He died on November 23, 1902, of the resulting peritonitis, at age 51. He was buried in Arlington National Cemetery.


Legacy

Reed's breakthrough in yellow fever research is widely considered a milestone in biomedicine, opening new vistas of research and humanitarianism. It was largely an extension of Carlos J. Finlay's work, carried out during the 1870s in Cuba, which finally came to prominence in 1900. Finlay was the first to theorize, in 1881, that a mosquito was a carrier, now known as a disease vector, of the organism causing yellow fever: a mosquito that bites a victim of the disease could subsequently bite and thereby infect a healthy person. He presented this theory at the 1881 International Sanitary Conference, where it was well received. A year later Finlay identified a mosquito of the genus '' Aedes'' as the organism transmitting yellow fever. His theory was followed by the recommendation to control the mosquito population as a way to control the spread of the disease. This discovery helped
William C. Gorgas William Crawford Gorgas KCMG (October 3, 1854 – July 3, 1920) was a United States Army physician and 22nd Surgeon General of the U.S. Army (1914–1918). He is best known for his work in Florida, Havana and at the Panama Canal in abating the ...
reduce the incidence and prevalence of mosquito-borne diseases in Panama during the American campaign, from 1903 onwards, to construct the Panama Canal. Prior to this, about 10% of the workforce had died each year from malaria and yellow fever. In 1912, he posthumously received what came to be known as the Walter Reed Medal in recognition of his work to combat yellow fever. A tropical medicine course is also named after him,
Walter Reed Tropical Medicine Course The Walter Reed Tropical Medicine Course (now called 'Operational Clinical Infectious Disease' Course ) at Walter Reed Army Institute of Research, Walter Reed Army Institute of Research (WRAIR) is one of the many Tropical Medicine Training Courses ...
. The National Library of Medicine in Bethesda, Maryland holds a collection of his papers regarding typhoid fever studies. Philip Showalter Hench, a Nobel Prize winner for Physiology or Medicine in 1950, maintained a long interest in Walter Reed and yellow fever. His collection of thousands of items—documents, photographs, and artifacts—is at the University of Virginia in the Philip S. Hench Walter Reed Yellow Fever Collection. More than 7,500 of these items, including several hundred letters written by Reed himself, are accessible online at the web exhibit devoted to this Collection. In addition to that medal, course, and a stamp issued in his honor (shown), locations and institutions named after the medical pioneer include: *
Walter Reed General Hospital The Walter Reed Army Medical Center (WRAMC)known as Walter Reed General Hospital (WRGH) until 1951was the U.S. Army's flagship medical center from 1909 to 2011. Located on in the District of Columbia, it served more than 150,000 active and reti ...
(WRGH), Washington, D.C. was opened on May 1, 1909, seven years after his death. It merged into the
Walter Reed National Military Medical Center The Walter Reed National Military Medical Center (WRNMMC), formerly known as the National Naval Medical Center and colloquially referred to as the Bethesda Naval Hospital, Walter Reed, or Navy Med, is a United States' tri-service military medi ...
, a new hospital complex constructed on the grounds of the National Naval Medical Center, Bethesda, Maryland, dedicated in 2011. * Reed Hall at Radford College (now
Radford University Radford University is a public university in Radford, Virginia. It is one of the state's eight doctorate-granting public universities. Founded in 1910, Radford offers curricula for undergraduates in more than 100 fields, graduate programs inclu ...
) was constructed in 1939 as the original home for the sciences and named for Dr. Walter Reed. It is now part of the Artis College for Science and Technology at Radford. * Walter Reed Army Medical Center (WRAMC) opened in 1977 as the successor to WRGH and closed in 2011; it was the worldwide tertiary care medical center for the U.S. Army and was utilized by congressmen and presidents. *
Walter Reed Army Institute of Research The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD). The institute is centered at the Forest Glen Annex, in the Forest Glen Park part of the uni ...
(WRAIR), near Washington, D.C., is the largest biomedical research facility administered by the DoD and successor to the Army Medical School. * Walter Reed Biosystematics Unit, operating under the direction of the
Walter Reed Army Institute of Research The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD). The institute is centered at the Forest Glen Annex, in the Forest Glen Park part of the uni ...
conducting research on the
systematics Biological systematics is the study of the diversification of living forms, both past and present, and the relationships among living things through time. Relationships are visualized as evolutionary trees (synonyms: cladograms, phylogenetic tre ...
of medically important
arthropods Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a Segmentation (biology), segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and Arth ...
. *
Walter Reed Birthplace Walter Reed Birthplace is a historic home located near Belroi, Gloucester County, Virginia. It was built around 1825 and is a one-story, gable-roofed frame dwelling. It has a rear shed addition. The house was restored in 1927 and again in 197 ...
, added to the National Register of Historic Places in 1973. * Riverside Walter Reed Hospital in Gloucester, Virginia (near Reed's birthplace) opened on September 13, 1977. * Arlington County, Virginia has two facilities named for Reed: the Reed School in Westover and a community/senior center near Walter Reed Drive in Arlington Village. * Walter Reed Middle School, North Hollywood, California is named in Reed's honor. * Walter Reed Army Medical Center Firefighters Washington D.C. IAFF F151 * Reed appears in sculpture on the great stone
chancel screen In church architecture, the chancel is the space around the altar, including the choir and the sanctuary (sometimes called the presbytery), at the liturgical east end of a traditional Christian church building. It may terminate in an apse. Over ...
at Riverside Church, NYC. (Section 4: "Humanitarians", rather than Section 1: "Physicians".) John Miltern portrayed Reed in the 1934 Broadway play, ''Yellow Jack,'' written by Pulitzer Prize winner Sidney Howard, in collaboration with Paul de Kuif . Harcourt Brace and Co. published the play in book form, titled ''Yellow Jack : A History'', in 1934.
Lewis Stone Lewis Shepard Stone (November 15, 1879 – September 12, 1953) was an American film actor. He spent 29 years as a contract player at Metro-Goldwyn-Mayer and was best known for his portrayal of Judge James Hardy in the studio's popular '' Andy ...
took the part in Metro-Goldwyn-Mayer's 1938 film adaptation of the play, '' Yellow Jack''. The play and screenplay were adapted for television in episodes (both titled "Yellow Jack") of ''Celanese Theatre'' (1952) and of '' Producers' Showcase'' (1955). In the latter, Reed was portrayed by
Broderick Crawford William Broderick Crawford (December 9, 1911 – April 26, 1986) was an American stage, film, radio, and television actor, often cast in tough-guy roles and best known for his Oscar- and Golden Globe-winning portrayal of Willie Stark in ''All t ...
.
Jeffrey Hunter Jeffrey Hunter (born Henry Herman McKinnies Jr.; November 25, 1926 – May 27, 1969) was an American film and television actor and producer known for his roles in films such as ''The Searchers'' and ''King of Kings (1961 film), King of Kin ...
played Reed in a 1962 episode of the anthology show '' Death Valley Days,'' titled "Suzie". In 2006, PBS's '' American Experience'' television series broadcast
"The Great Fever"
a program exploring Reed's yellow fever campaign. The PBS website contains a great deal of additional information, including links to primary sources. Reed's name is featured on the frieze of the London School of Hygiene & Tropical Medicine. Twenty-three names of public health and tropical medicine pioneers were originally chosen to be displayed on the School building in Keppel Street when it was constructed in 1926.


See also

* Human experimentation in the United States


References


Further reading

* Bean, William B., ''Walter Reed: A Biography'', Charlottesville: University Press of Virginia, 1982. * Bean, William B., "Walter Reed and Yellow Fever", '' JAMA'' 250.5 (August 5, 1983): 659–62. * Pierce J.R., (2005). ''Yellow Jack: How Yellow Fever Ravaged America and Walter Reed Discovered its Deadly Secrets''. John Wiley and Sons. *


External links


WRAMC Website Reed History

WRAIR Website Reed History

University of Virginia, Philip S. Hench – Walter Reed Yellow Fever Collection: Walter Reed Biography

University of Virginia, Yellow Fever and the Reed Commission: The Walter Reed Commission

University of Virginia, Walter Reed Typhoid Fever, 1897–1911


at ArlingtonCemetery.net, an unofficial website {{DEFAULTSORT:Reed, Walter 1851 births 1902 deaths Burials at Arlington National Cemetery Congressional Gold Medal recipients American entomologists Methodists from Virginia George Washington University faculty University of Virginia School of Medicine alumni New York University Grossman School of Medicine alumni Deaths from peritonitis Human subject research in the United States United States Army Medical Corps officers People from Gloucester County, Virginia Hall of Fame for Great Americans inductees Scientists from Virginia Yellow fever