Walborg Thorsell
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Walborg Susanna Thorsell (12 February 1919 – January 2016) was a Swedish scientist who performed research mainly on
mosquito Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning " gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "li ...
es and mosquito repellents.


Education

Thorsell defended her thesis for her
doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ...
in
veterinary medicine Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutri ...
at the Swedish Veterinarian Institute in 1967, and was a
docent The title of docent is conferred by some European universities to denote a specific academic appointment within a set structure of academic ranks at or below the full professor rank, similar to a British readership, a French " ''maître de conf ...
in experimental
parasitology Parasitology is the study of parasites, their hosts, and the relationship between them. As a biological discipline, the scope of parasitology is not determined by the organism or environment in question but by their way of life. This means it fo ...
.


Research

Thorsell started her studies on mosquitoes while working at the
Swedish National Defence Research Institute Swedish National Defence Research Institute ( sv, Försvarets forskningsanstalt, FOA) was a Swedish government agency in defense research existing from 1945 to 31 December 2000. It was amalgamated with the National Aeronautical Research Institute ...
(FOA). At that time claims circulated, from both the United States and the Soviet Union, that the other part was conducting experiments with malaria mosquitos in relations to
biological warfare Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm or incapacitate humans, animals or plants as an act of war. Bio ...
. The Swedish military therefore felt it necessary to develop a mosquito repellent, especially for malaria mosquitoes, to be used by Swedish soldiers. The existing repellents were either not efficient enough or had unwanted side effects, so Thorsell and her group of researchers at FOA began looking for a better agent. The substance ''diethylamide'' proved to be an excellent repellent for both malaria mosquitoes and ordinary Swedish forest mosquitoes. But in its unmodified form, it is water-soluble and was washed away by the sweat when applied on the soldiers. Thorsells' solution to this was to add the same
functional group In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the rest ...
s as in ''diethylamide'' to
mandelic acid Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H. It is a white crystalline solid that is soluble in water and polar organic solvents. It is a useful precursor to various drugs. The molecule is chiral. Th ...
. This resulted in a mosquito repellent called ''DEMIDEX'', that was manufactured during a number of years. ''DEMIDEX'' was more efficient than the American
DEET ''N'',''N''-Diethyl-''meta''-toluamide, also called DEET () or diethyltoluamide, is the most common active ingredient in insect repellents. It is a slightly yellow oil intended to be applied to the skin or to clothing and provides protection ag ...
, which was and still is the most common active ingredient in insect repellents. After retiering from FOA, Thorsell continued her research on mosquito repellents at the Department of Zoology at
Stockholm University Stockholm University ( sv, Stockholms universitet) is a public research university in Stockholm, Sweden, founded as a college in 1878, with university status since 1960. With over 33,000 students at four different faculties: law, humanities, so ...
. That research resulted in the repellent ingredient ''IXNIX''. She died in January 2016 at the age of 96.


Honours

A family of bacteria, ''
Thorselliaceae Thorselliaceae is a family of bacteria belonging to the class Gammaproteobacteria and it was first described in February 2015. It is not assigned to an order. The family consists of four species in two genera. The bacteria are Gram-negative and r ...
'', found in
vector Vector most often refers to: *Euclidean vector, a quantity with a magnitude and a direction *Vector (epidemiology), an agent that carries and transmits an infectious pathogen into another living organism Vector may also refer to: Mathematic ...
mosquitoes, mainly with vectors of
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, has been named after Thorsell. The family contains the genus '' Thorsellia'' of which three species are known so far.


Bibliography

A selection. * ''Krigsepidemiologi och hälsovård för totalförsvaret: dokumentation från FOA informationsdag, översiktsdag, Stockholm, 1982-05-05'' (Warfare epidemiology and health care within the Swedish total defence : documentation from the FOA conference, Stockholm, 82-05-05) 1983 * ''Människans fysiska tålighet i brandmiljö: brandgaser och rök'' (Man's physical tolerance in fires: fumes and smoke) 1984 * ''Människan och ohyran - bekämpningsmedel i Sverige förr och nu'' (Man and Vermin - pesticides in Sweden, past and present) 2001


References


Further reading

* {{DEFAULTSORT:Thorsell, Walborg 1919 births 2016 deaths Swedish women biologists Swedish parasitologists 20th-century Swedish scientists 20th-century women scientists 20th-century biologists 20th-century Swedish women