Vlado Perkovic
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Vlado Perkovic (born March 8, 1969) is an Australian
renal The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and
researcher Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness ...
who is the Dean of the Faculty of Medicine at the
University of New South Wales The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...
, Sydney. He is also a Honorary Fellow at the
George Institute for Global Health The George Institute for Global Health, is an independent medical research institute headquartered in Australia with offices in China, India and the United Kingdom. The George Institute conducts research on non-communicable disease, including hea ...
Australia, and a board member and scientific leader at George Clinical, the commercial
clinical research Clinical research is a branch of healthcare science that determines the safety and effectiveness ( efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatm ...
arm of The
George Institute for Global Health The George Institute for Global Health, is an independent medical research institute headquartered in Australia with offices in China, India and the United Kingdom. The George Institute conducts research on non-communicable disease, including hea ...
, where he provides trial design and management expertise for a variety of
clinical trials Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietar ...
.


Career

Perkovic moved to Sydney and into professional academia after completing his PhD in 2005. The thesis undertaken at the University of Melbourne was entitled “The Cardiovascular Aspects of Kidney Disease”. Perkovic relocated to Sydney to take on a position as Associate Principal Director at The George Institute for Global Health (2007-2008), and was appointed Conjoint Senior Lecturer at the University of Sydney. Perkovic worked in a number of senior research and executive positions at The George Institute, before being appointed Executive Director of The George Institute, Australia in 2012. In 2017 Perkovic was appointed to lead the non-communicable diseases theme as part of the
University of New South Wales The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...
Medicine's thematic research strategy. In 2019, he was appointed as the Dean of Medicine at
University of New South Wales The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...
. From 2009-2014 Perkovic was the Executive Director of George Clinical, one of The George Institute's commercial enterprises. He was appointed to the board of George Clinical in 2010 and holds this position today. Perkovic regularly appears in the media worldwide as an authority in the fields
hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...
,
cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...
, and clinical trials. His research is widely cited and has been responsible for changing medical guidelines. He has an increasing advocacy and media profile, with a number of op-eds in major newspapers, as well as chairing a number of roundtables and interviews. For example, Perkovic shared the stage with Dr Jim Kim, President of The World Bank, when he visited Sydney in 2014. Perkovic is a fellow of the
Royal Australasian College of Physicians The Royal Australasian College of Physicians (RACP) is a not-for-profit professional organisation responsible for training and educating physicians and paediatricians across Australia and New Zealand. The RACP is responsible for training both ...
(1999), the
American Society of Nephrology Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical r ...
, (2008) and the
Australian Academy of Health and Medical Sciences The Australian Academy of Health and Medical Sciences is an academy to promote health and medical sciences in Australia. It was established in June 2014. It cites "The Academy will serve the three purposes identified as of high priority in the 20 ...
(2016). He holds a
National Health and Medical Research Council The National Health and Medical Research Council (NHMRC) is the main statutory authority of the Australian Government responsible for medical research. It was the eighth largest research funding body in the world in 2016, and NHMRC-funded rese ...
program grant. Some of Perkovic's previous positions include being President of the Association of Australian Medical Research Institutes (AAMRI, the peak body for Medical Research Institutes), Chairman of the
International Society of Nephrology The International Society of Nephrology (ISN) is an organization concerned with kidney health. Introduction The ISN has over 9,000 professional members from more than 156 countries. In addition, the ISN closely collaborates with over 100 nation ...
Advancing Clinical Trials initiative (ISN-ACT 2016-), a member of the Executive Committee and Board of Australian Clinical Trials Alliance, (2016-8), a member of the Executive Operations Secretariat, Australasian Kidney Trials Network (2016-) and Chair of the AKTN Scientific Committee 2013-6. He was previously a member of the Health Translation Advisory Committee (HTAC) of the National Health and Medical Research Council (2015-8)


Research Focus and Publications

Perkovic has published more than 250 peer reviewed papers, and his career has been based on clinical research investigating the prevention and treatment of
kidney disease Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can ...
, and its complications. As well as
epidemiological research Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
identifying important risk factors, Perkovic has led a broad suite of clinical trials and
meta-analyses A meta-analysis is a statistical analysis that combines the results of multiple scientific studies. Meta-analyses can be performed when there are multiple scientific studies addressing the same question, with each individual study reporting me ...
aiming to identify effective interventions that slow the progression of kidney disease and reduce the risk of developing the many complications of kidney disease. Some of Perkovic's key outputs here have been work on
diabetic nephropathy Diabetic nephropathy, also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease ...
published in a range of journals, and studies of blood pressure lowering, lipid lowering and a range of other interventions for the prevention of kidney failure and cardiovascular outcomes in people with kidney disease. Perkovic's ongoing work includes further systematic reviews, large scale global trials of steroids for the prevention of kidney failure in IgA nephropathy (Co-Principal Investigator), and Steering Committee roles in a number of global, pharma-funded trials studying treatments for the prevention of
kidney failure Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as eit ...
in diabetic nephropathy. This includes a role as Chair of the CREDENCE trial Steering Committee, the first trial to convincingly demonstrate the benefits of the SGLT2 inhibitor
canagliflozin Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exe ...
on the risk of kidney failure and
cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
outcomes in people with diabetes and kidney disease. Perkovic's research has led to major publications in the New England Journal of Medicine, Lancet, BMJ, Annals of Internal Medicine, PLoS Medicine and a range of specialty journals. He was appointed to the Editorial Board of the New England Journal of Medicine in 2017, the first Australian to receive this honour.


Personal life

Perkovic was born in Brinje, Croatia and moved to Australia with his family before the age of one. He lived in Melbourne and trained in medicine at the University of Melbourne and the Royal Melbourne Hospital, receiving his
MBBS Bachelor of Medicine, Bachelor of Surgery ( la, Medicinae Baccalaureus, Baccalaureus Chirurgiae; abbreviated most commonly MBBS), is the primary medical degree awarded by medical schools in countries that follow the tradition of the United King ...
and
Doctor of Philosophy A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common Academic degree, degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields ...
qualifications from The
University of Melbourne The University of Melbourne is a public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in Victoria. Its main campus is located in Parkville, an inner suburb nor ...
in 1992 and 2005 respectively. He is married with three sons. Prior to pursuing a career in academia, he worked as a
nephrologist Nephrology (from Greek'' nephros'' "kidney", combined with the suffix ''-logy'', "the study of") is a specialty of adult internal medicine and pediatric medicine that concerns the study of the kidneys, specifically normal kidney function (ren ...
and general physician at the
Royal Melbourne Hospital The Royal Melbourne Hospital (RMH), located in Parkville, Victoria, an inner suburb of Melbourne, is one of Australia's leading public hospitals. It is a major teaching hospital for tertiary health care with a reputation in clinical research. Th ...
, (2002-2005), and was appointed Head of
Haemodialysis Hemodialysis, also spelled haemodialysis, or simply dialysis, is a process of purifying the blood of a person whose kidneys are not working normally. This type of dialysis achieves the extracorporeal removal of waste products such as creatinin ...
for the North West Dialysis Service, Royal Melbourne Hospital. From 2005 when he moved to
Sydney Sydney ( ) is the capital city of the state of New South Wales, and the most populous city in both Australia and Oceania. Located on Australia's east coast, the metropolis surrounds Sydney Harbour and extends about towards the Blue Mountain ...
, Perkovic has held a part-time appointment as a specialist in
nephrology Nephrology (from Greek'' nephros'' "kidney", combined with the suffix ''-logy'', "the study of") is a specialty of adult internal medicine and pediatric medicine that concerns the study of the kidneys, specifically normal kidney function (ren ...
and
hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...
at the
Royal North Shore Hospital The Royal North Shore Hospital (RNSH) is a major public teaching hospital in Sydney, Australia, located in St Leonards. It serves as a teaching hospital for Sydney Medical School at the University of Sydney and has over 600 beds. It is the prin ...
, Sydney.


References


External links


Vlado Perkovic Google Scholars CitationsGeorge InstituteGeore Clinical
{{DEFAULTSORT:Perkovic, Vlado Australian nephrologists Australian people of Croatian descent 1969 births Living people