The vimentin 3′ UTR protein-binding region is an
RNA element that contains a Y-shaped structure which has been shown to have
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
-binding activity. The same region has been implicated in the control of
mRNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein.
mRNA is ...
localisation to the perinuclear region of the
cytoplasm
In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus. The material inside the nucleus and contained within the nuclear membrane is termed the nucleoplasm. The ...
, possibly at sites of intermediate filament assembly.
The identity of the proteins involved and the localisation mechanism are not known.
References
External links
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Transterm page for Vimentin Localisation Element
Cis-regulatory RNA elements
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