Vesnarinone ( INN) is a

cardiotonic A cardiac stimulant is a substance which acts as a stimulant of the heart – e.g., via positive chronotropic or inotropic action. Examples of cardiac stimulant drugs are cocaine and methamphetamine Methamphetamine (contracted from ) is a p ...

agent. A mixed

phosphodiesterase 3 inhibitor A PDE3 inhibitor is a drug which inhibits the action of the phosphodiesterase enzyme PDE3. They are used for the therapy of acute heart failure and cardiogenic shock. Medical uses Cardiac Amrinone, milrinone and enoximone are used clinically f ...

and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. Vesnarinone improves ventricular performance most in patients with the worst degree of

heart failure Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, a ...

References

External links

* N-benzoylpiperazines Inotropic agents PDE3 inhibitors Catechol ethers Phenylpiperazines 2-Quinolones {{cardiovascular-drug-stub