Very-long-chain (3R)-3-hydroxyacyl-(acyl-carrier Protein) Dehydratase
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Very-long-chain (3''R'')-3-hydroxyacyl-CoA dehydratase (, ''PHS1 (gene)'', ''PAS2 (gene)'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
''very-long-chain (3''R'')-3-hydroxyacyl-CoA hydro-lyase''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: a very-long-chain (3''R'')-3-hydroxyacyl-CoA \rightleftharpoons a very-long-chain ''trans''-2,3-dehydroacyl-CoA + H2O This is the third component of the
elongase Elongase is a generic term for an enzyme that catalyzes carbon chain extension of an organic molecule, especially a fatty acid In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either ...
.


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* {{Portal bar, Biology, border=no EC 4.2.1