Vernolepin is a

sesquiterpene lactone Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) an ...

isolated from the dried fruit of ''

Vernonia amygdalina ''Vernonia amygdalina'', a member of the daisy family, is a small shrub that grows in tropical Africa. ''V. amygdalina'' typically grows to a height of . The leaves are elliptical and up to long. Its bark is rough. ''V. amygdalina'' is common ...

''. It shows platelet anti-aggregating properties and is also an irreversible

DNA polymerase A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create ...

inhibitor, hence may have

antitumor Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...

properties.

References

{{Organic-compound-stub Sesquiterpene lactones Secondary alcohols Alkene derivatives DNA polymerase inhibitors