Valerie Daggett is a

professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...

bioengineering Biological engineering or bioengineering is the application of principles of biology and the tools of engineering to create usable, tangible, economically-viable products. Biological engineering employs knowledge and expertise from a number o ...

at the

University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...

Seattle Seattle ( ) is a seaport city on the West Coast of the United States. It is the seat of King County, Washington. With a 2020 population of 737,015, it is the largest city in both the state of Washington and the Pacific Northwest regio ...

Washington Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered o ...

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

Education and career

Daggett has a B.S. from

Reed College Reed College is a private liberal arts college in Portland, Oregon. Founded in 1908, Reed is a residential college with a campus in the Eastmoreland neighborhood, with Tudor-Gothic style architecture, and a forested canyon nature preserve at ...

. She received her Ph.D. from the

University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It con ...

, advised by Irwin Kuntz and

Peter Kollman Peter Andrew Kollman (July 24, 1944–May 25, 2001) was a professor of chemistry and pharmaceutical chemistry at the University of California, San Francisco. He is known for his work in computational chemistry, molecular modeling and bioinfo ...

, and subsequently held a postdoctoral position at

Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...

with

Michael Levitt Michael Levitt, ( he, מיכאל לויט; born 9 May 1947) is a South African-born biophysicist and a professor of structural biology at Stanford University, a position he has held since 1987. Levitt received the 2013 Nobel Prize in Chemistr ...

, a co-recipient of the 2013

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

. As of 2021, she is also the chief executive officer of AltPep, a biomedical startup that was a spinoff from her research at the University of Washington.

Research

Her laboratory focuses on work in

molecular dynamics Molecular dynamics (MD) is a computer simulation method for analyzing the physical movements of atoms and molecules. The atoms and molecules are allowed to interact for a fixed period of time, giving a view of the dynamic "evolution" of the ...

simulations of

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

s and other biomolecules. Daggett is well known for large-scale simulations of

protein folding Protein folding is the physical process by which a protein chain is translated to its native three-dimensional structure, typically a "folded" conformation by which the protein becomes biologically functional. Via an expeditious and reproduc ...

, especially unfolding, and native state dynamics through her "dynameomics" project. In 2005, the Daggett laboratory was awarded a supercomputing grant by the U.S.

Department of Energy A Ministry of Energy or Department of Energy is a government department in some countries that typically oversees the production of fuel and electricity; in the United States, however, it manages nuclear weapons development and conducts energy-re ...

, which was renewed for almost two million processor-hours in 2006; the group has also participated in

Microsoft Research Microsoft Research (MSR) is the research subsidiary of Microsoft. It was created in 1991 by Richard Rashid, Bill Gates and Nathan Myhrvold with the intent to advance state-of-the-art computing and solve difficult world problems through technologi ...

high-performance computing High-performance computing (HPC) uses supercomputers and computer clusters to solve advanced computation problems. Overview HPC integrates systems administration (including network and security knowledge) and parallel programming into a mult ...

projects.

Awards and honors

In 2011, Daggett was named a fellow of the Biophysical Society. Daggett was one of two University of Washington scientists named 2015

American Institute for Medical and Biological Engineering The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington. It represents 50,000 medical and biomedical engineers, and academic institutions, private industry, ...

fellows.

References

External links

Daggett Laboratory website
21st-century American biologists 21st-century American women scientists American women biochemists American women biologists Fellows of the American Institute for Medical and Biological Engineering Living people Year of birth missing (living people) {{US-biochemist-stub