Valentín Fuster Carulla, 1st Marquess of Fuster (born January 20, 1943) is a Spanish

cardiologist Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular ...

and aristocrat. He is

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ...

of the ''

Journal of the American College of Cardiology The ''Journal of the American College of Cardiology'' is a peer-reviewed medical journal covering all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the-a ...

'' (JACC), past President of the American Heart Association, past President of the

World Heart Federation The World Heart Federation (WHF) is a non-governmental organization based in Geneva, Switzerland, formed in 1972. The current President for World Heart Federation is Fausto Pinto. In 1978 the International Society of Cardiology merged with the In ...

, Editor-in-Chief, ''

'' and has been a member of the US

National Academy of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Eng ...

and Member of the European Horizon 2020 Scientific Panel of Health. In 2016 he co-chaired, with

Jendayi Frazer Jendayi Elizabeth Frazer (born 1961) is the former U.S. Assistant Secretary of State for African Affairs, heading the Bureau of African Affairs. She was a Distinguished Service Professor at Carnegie Mellon University's Heinz College and Departm ...

, the Advisory Committee on ''The Role of the United States on Global Health''. Fuster serves as President of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, and Director of the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, and the Richard Gorlin, MD/Heart Research Foundation Professor at

Icahn School of Medicine at Mount Sinai The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eig ...

."Doctor Profile", Mount Sinai Hospital
retrieved May 13, 2015 He serves in

Madrid Madrid ( , ) is the capital and most populous city of Spain. The city has almost 3.4 million inhabitants and a Madrid metropolitan area, metropolitan area population of approximately 6.7 million. It is the Largest cities of the Europ ...

as the General Director of the National Centre for Cardiovascular Research (CNIC)Centro Nacional de Investigaciones Cardiovasculare and also chairs an international project, the SHE Foundation (Science for Health and Education). In 2014,

King Juan Carlos I Juan Carlos I (;, * ca, Joan Carles I, * gl, Xoán Carlos I, Juan Carlos Alfonso Víctor María de Borbón y Borbón-Dos Sicilias, born 5 January 1938) is a member of the Spanish royal family who reigned as King of Spain from 22 Novem ...

of Spain granted him the title of Marquis for his "outstanding and unceasing research efforts and his educational outreach work".

Life and career

Fuster was born in Barcelona, Spain. He is the son of a psychiatrist, and his brother is a

neuroscientist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial ...

. In Spain he competed in tennis at a national level. Pedro Farreras Valentí, the author of the widely used Spanish textbook ''Farreras-Rozman Internal Medicine'', encouraged Fuster to study cardiology. Fuster graduated first in his class with an MD from

University of Barcelona The University of Barcelona ( ca, Universitat de Barcelona, UB; ; es, link=no, Universidad de Barcelona) is a public university located in the city of Barcelona, Catalonia, in Spain. With 63,000 students, it is one of the biggest universities i ...

in 1967. He completed an internship at the Hospital Clinic in Barcelona, then attended

University of Edinburgh Medical School The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the University of Edinburgh College of Medicine and Veterinar ...

for a PhD on the role of

platelet Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby i ...

s in

myocardial Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle that ...

infarction Infarction is tissue death ( necrosis) due to inadequate blood supply to the affected area. It may be caused by artery blockages, rupture, mechanical compression, or vasoconstriction. The resulting lesion is referred to as an infarct (from th ...

. Fuster served as a Research Fellow in Cardiology at the

Royal Infirmary of Edinburgh The Royal Infirmary of Edinburgh, or RIE, often (but incorrectly) known as the Edinburgh Royal Infirmary, or ERI, was established in 1729 and is the oldest voluntary hospital in Scotland. The new buildings of 1879 were claimed to be the largest v ...

from 1968 to 1971 After completing his PhD in 1971 from the

. Fuster spent several years at the Mayo Clinic, first as a resident and later as Professor of Medicine and Consultant in Cardiology. In 1981, he became head of cardiology at Mount Sinai School of Medicine. From 1991 to 1994, he was Mallinckrodt Professor of Medicine at

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

and Chief of Cardiology at the Massachusetts General Hospital. He returned to Mount Sinai in 1994 as Director of the Zena and Michael A. Wiener Cardiovascular Institute and in 2006 named the Director of Mount Sinai Heart, and in 2022, he was appointed president. Fuster serves as physician-in-chief and President of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josee and Henry R. Kravis Center for Cardiovascular Health. He is also the

Richard Gorlin Richard Gorlin (June 30, 1926 – October 16, 1997) was an American cardiologist known for his contributions to the fields of valvular heart disease, coronary artery disease and cardiac catheterization, digitalis and vasodilators in congestive h ...

, MD/Heart Research Foundation Professor at

. Fuster was the President of Science, and is now the General Director of the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) in

, (Spain)."Valentin Fuster Carulla", CNIC
retrieved March 12, 2013 Fuster was elected

at the ''

'' in 2014. Former positions include President of the American Heart Association, past president of the

, member of the Institute of Medicine of the National Academy of Sciences where he serves as Chair of the Committee on Preventing the Global Epidemic of Cardiovascular Disease, former member of the National Heart, Lung, and Blood Institute Advisory Council, and former Chairman of the Fellowship Training Directors Program of the

American College of Cardiology The American College of Cardiology (ACC), based in Washington, D.C., is a nonprofit medical association established in 1949. It bestows credentials upon cardiovascular specialists who meet its qualifications. Education is a core component of the ...

. He has thirty-four university Honorary Doctorates. According to Google Scholar, his peer-reviewed publications, as of 2020, have been cited 319,356. His h-index is 209 and i10-index is 1,206. He was the inspiration for a character on the Spanish version of ''

Sesame Street ''Sesame Street'' is an American educational children's television series that combines live-action, sketch comedy, animation and puppetry. It is produced by Sesame Workshop (known as the Children's Television Workshop until June 2000) ...

'' named "Valentin Ruster" that educated children in healthier lifestyles through exercise and healthy diet.

Honors and awards

* 1992 Andreas Gruntzig Award of the International Society of Interventionalists (Paris)"Valentin Fuster Honored with Grand Prix Award", TheHeart
retrieved March 21, 2013 *1993 Distinguished Scientist Award, American College of Cardiology"Previous Years Distinguished Scientists", American Heart Association
retrieved March 21, 2013 * 1996 Principe de Asturias Award of Science and Technology, Fundacion Principe de Asturias, Oviedo, Spain * 2001 James B. Herrick Award, Council of Clinical Cardiology of the American Heart Association * 2005 2009 Distinguished Researcher Award, Interamerican Society of Cardiology * 2008 Polzer Prize, European Academy of Science and Arts * 2011 The LeFoulon Delalande Grand Prize, Institute of France, Paris, France * 2012 AHA Research Achievement Award, Los Angeles, CA"New York City scientist wins American Heart Association award for major additions to knowledge of artery disease process, treatments", American Heart Association
retrieved March 12, 2013 * 2014 Made ''Marquess of Fuster'' in the

Spanish nobility Spanish nobles are persons who possess the legal status of hereditary nobility according to the laws and traditions of the Spanish monarchy and historically also those who held personal nobility as bestowed by one of the three highest orders of ...

by King Juan Carlos I. * 2017 Knight Grand Cross of the Civil Order of Alfonso X, the Wise *2020

Prince Mahidol Award The Prince Mahidol Award ( th, รางวัลสมเด็จเจ้าฟ้ามหิดล) is an annual award for outstanding achievements in medicine and public health worldwide. The award is given by the Prince Mahidol Award Found ...

in Medicine

Scientific investigator

Contributions in
translational medicine Translational medicine (often called translational science, of which it is a form) is defined by the European Society for Translational Medicine as "an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, bed ...

Chronology Fuster’s contributions for disease-to-health transitions encompass five phases leading to 4 guidelines Class I: 1980s: Demonstrating the role of platelets in coronary artery bypass graft ( CABG) occlusion based on imaging studies in dogs, and a pioneering trial of aspirin in human atherothrombotic disease. 1990s: Demonstrating that acute coronary events arise from small plaques, explaining their unpredictability, and developing diagnostic MRI imaging to characterize these “vulnerable plaques” and inhibiting post coronary angioplasty (PCI) fibrosis in pigs by

Rapamycin Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosi ...

, prompting the introduction of

drug-eluting stent A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly release a drug to block cell proliferation. This prevents fibrosis that, together with clots ( ...

s (DES) to prevent PCI

restenosis Restenosis is the recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage and s ...

. 2000s: Following upon experience with CABG and DES for

revascularization In medical and surgical therapy, revascularization is the restoration of perfusion to a body part or organ that has had ischemia. It is typically accomplished by surgical means. Vascular bypass and angioplasty are the two primary means of rev ...

in patients with diabetes and multivessel coronary disease changing American and European practice guidelines. 2010s: To improve poor medication adherence, as observed in FREEDOM and other studies, a fixed-dose

polypill A polypill is a type of drug combination consisting of a single drug product in pill form (i.e., tablet or capsule) and thus ''combines'' multiple medications (that is, more than one active pharmaceutical ingredient). The prefix "poly" means "mu ...

(aspirin,

ramipril Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 yea ...

and

statin Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs. Low ...

) was developed, the first approved for secondary prevention in 40 countries. 2015 to present (2021): Established the predictive value of identifying atherosclerotic burden by noninvasive imaging (3D ultrasound, EBCT, PET, MRI) and genetics in 4 studies of 11,000 asymptomatic adults. Thus, in collaboration with the producers of Sesame Street television, conducted randomized studies of 3,000 children, 2,000 parents and 300 teachers in Colombia,

Spain , image_flag = Bandera de España.svg , image_coat = Escudo de España (mazonado).svg , national_motto = ''Plus ultra'' (Latin)(English: "Further Beyond") , national_anthem = (English: "Royal March") , i ...

and

Harlem Harlem is a neighborhood in Upper Manhattan, New York City. It is bounded roughly by the Hudson River on the west; the Harlem River and 155th Street on the north; Fifth Avenue on the east; and Central Park North on the south. The greater Ha ...

(New York). Sixty hours of health education over six months showed a significant impact on knowledge, attitude, habits and weight within three years.

Books

Author

*Hurst's the ''Heart Manual of Cardiology'', 12th Edition by Robert O'Rourke, Richard Walsh and Valentin Fuster (Jan 27, 2009) *''The Heart Manual: My Scientific Advice for Eating Better, Feeling Better, and Living a Stress-Free Life Now'' by Valentin Fuster (Feb 2, 2010) *The ''AHA Guidelines and Scientific Statements Handbook'' (Fuster, The AHA Guidelines And Scientific Statements Handbook) by Valentin Fuster (Jan 6, 2009) *''Atherothrombosis and Coronary Artery Disease'' by Valentin Fuster, Eric J. Topol and Elizabeth G. Nabel (Nov 8, 2004) *Platelets in Thrombotic and Non-Thrombotic Disorders Pathophysiology, Pharmacology and Therapeutics Paolo Gresele, Clive P. Page, Valentin Fuster, Jos Vermylen Hardback () *Thrombosis in Cardiovascular Disorders ardcoverValentin Fuster (Author), Marc Verstraete (Author) *Update on Coronary Risk Factors, An Issue of Medical Clinics of North America ardcoverValentin Fuster, MD, PhD (Author), and Jagat Narula *La Ciencia de la Salud: Mis consejos para una vida sana (Spanish Edition) by Valentin Fuster (Dec 26, 2007) *Cardiovascular Thrombosis: Thrombocardiology and Thromboneurology ardcoverMarc Verstraete (Author), Valentin Fuster (Author), Fuster (Author) *La ciencia y la vida/ Science And Life (Spanish Edition) aperbackValentin Fuster (Author), Jose Luis Sampedro (Author) *[Cardiovascular Magnetic Resonance: Established and Emerging Applications ardcoverAlbert Lardo (Author), Zahi Fayad (Author), Nicolas Chronos (Author), Valentin Fuster (Author) *La pequeña ciencia de la salud erfect PaperbackValentin Fuster (Author) *Monstruos supersanos erfect PaperbackValentin Fuster (Author) *La cocina de la salud by Valentín Fuster / Ferran Adrià / Josep Corbella (2010) *La vostra salute mi sta a cuore erfect PaperbackJosep Corbella Valentín Fuster *La buona cucina della salute. La ricetta di un famoso chef e di un grande medico per vivere bene senza rinunce erfect PaperbackValentin Fuster, Josep Corbella Ferran Adrià (Author) *El Círculo de la motivación laneta de LibrosValentín Fuster con la colaboracíon de Emma Reverter

Editor

*The Vulnerable Atherosclerotic Plaque: Understanding, Identification and Modification ardcoverValentin Fuster (Editor) *Evolving Challenges in Promoting Cardiovascular Health by Annals of the New York Academy of Sciences Editorial Staff, Valentin Fuster (Editor) May 2012, Paperback *Assessing and Modifying the Vulnerable Atherosclerotic Plaque by Valentin Fuster (Editor) with William Insull Jr., MD June 2002, Hardcover *Oxidative Stress and Cardiac Failure by Marrick Kukin (Editor), Valentin Fuster (Editor) October 2002, Hardcover *Platelets in Hematologic and Cardiovascular Disorders: A Clinical Handbook ardcoverPaolo Gresele (Editor), Valentin Fuster (Editor), Jose A. Lopez (Editor), Clive P. Page (Editor), Jos Vermylen (Editor) *Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health] aperbackCommittee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries (Author), Institute of Medicine (Author), Valentin Fuster (Editor), Bridget B. Kelly (Editor) *Syndromes of Atherosclerosis: Correlations of Clinical Imaging and Pathology ardcoverValentin Fuster (Editor) *Efficacy of Myocardial Infarction Therapy ardcoverValentin Fuster (Editor) *Editor-in-chief of ''Nature Reviews Cardiology'', April 2009

References

External links

Mount Sinai Hospital homepageSHE Foundation
{{DEFAULTSORT:Fuster, Valentin 1940s births Spanish emigrants to the United States Living people Harvard Medical School faculty Icahn School of Medicine at Mount Sinai faculty People from Barcelona Recipients of the Civil Order of Alfonso X, the Wise Spanish cardiologists University of Barcelona alumni Alumni of the University of Edinburgh Fellows of the American College of Cardiology Members of the National Academy of Medicine