UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diamino-pimelate Ligase

UDP-''N''-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase (, ''MurE synthetase'', ''UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming)'', ''UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase'', ''UDP-N-acetylmuramoylalanyl-D-glutamate—2,6-diaminopimelate ligase'') is an enzyme with systematic name ''UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)''. This enzyme catalyses the following chemical reaction

: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate $\rightleftharpoons$ ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate

This enzyme takes part in synthesis of a cell-wall peptide.

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EC 6.3.2