enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

, an UDP-N-acetylglucosamine diphosphorylase () is an enzyme that

catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...

the chemical reaction :UTP + N-acetyl-alpha-D-glucosamine 1-phosphate

\rightleftharpoons

diphosphate + UDP-N-acetyl-D-glucosamine Thus, the two substrates of this enzyme are UTP and products are diphosphate">product_(chemistry).html" ;"title="-acetyl-alpha-D-glucosamine 1-phosphate, whereas its two product (chemistry)">products are diphosphate and UDP-N-acetyl-D-glucosamine. This enzyme participates in aminosugars metabolism.

Nomenclature

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase. Other names in common use include UDP-N-acetylglucosamine pyrophosphorylase, uridine diphosphoacetylglucosamine pyrophosphorylase, UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate, uridylyltransferase, UDP-GlcNAc pyrophosphorylase, GlmU uridylyltransferase, Acetylglucosamine 1-phosphate uridylyltransferase, UDP-acetylglucosamine pyrophosphorylase, uridine diphosphate-N-acetylglucosamine pyrophosphorylase, uridine diphosphoacetylglucosamine phosphorylase, and acetylglucosamine 1-phosphate uridylyltransferase.

References

* * EC 2.7.7 Enzymes of known structure {{2.7-enzyme-stub