Uveal autoantigen with coiled-coil domains and ankyrin repeats is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

that in humans is encoded by the ''UACA''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

. Diseases associated with UACA include

Graves' Disease Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyr ...

. Among its related pathways are signaling by Rho GTPases and Intrinsic Pathway for Apoptosis. An important paralog of this gene is

ANKRD24 Ankyrin repeat domain-containing protein 24 is a protein in humans that is coded for by the ''ANKRD24'' gene. The gene is also known as ''KIAA1981'.'' The protein's function in humans is currently unknown. ANKRD24 is in the protein family that c ...

References

Further reading