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Third-party reproduction or donor-assisted reproduction is any
human reproduction Human reproduction is sexual reproduction that results in human fertilization to produce a human offspring. It typically involves sexual intercourse between a sexually mature human male and female. During sexual intercourse, the interaction ...
in which DNA or
gestation Gestation is the period of development during the carrying of an embryo, and later fetus, inside viviparous animals (the embryo develops within the parent). It is typical for mammals, but also occurs for some non-mammals. Mammals during pr ...
is provided by a third party or donor other than the one or two
parent A parent is a caregiver of the offspring in their own species. In humans, a parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A ''biological parent'' is a person whose gamete resulted in a child, a male t ...
s who will raise the resulting child. This goes beyond the traditional
father A father is the male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental, legal, and social relationship with the child that carries with it certain rights and obligations. An adoptive fathe ...
mother ] A mother is the female parent of a child. A woman may be considered a mother by virtue of having given birth, by raising a child who may or may not be her biological offspring, or by supplying her ovum for fertilisation in the case of ...
model, and the third party's involvement is limited to the reproductive process and does not extend into the raising of the child. Third-party reproduction is used by couples unable to reproduce by traditional means, by
same-sex couple A same-sex relationship is a romantic or sexual relationship between people of the same sex. '' Same-sex marriage'' refers to the institutionalized recognition of such relationships in the form of a marriage; civil unions may exist in countries ...
s, and by men and women without a partner. Where donor gametes are provided by a donor, the donor will be a biological parent of the resulting child, but in third party reproduction, he or she will not be the caring parent.


Categories

One can distinguish several categories, some of which may be combined: *
Sperm donation Sperm donation is the provision by a man of his sperm with the intention that it be used in the artificial insemination or other 'fertility treatment' of a woman or women who are not his sexual partners in order that they may become pregnant by ...
. A donor provides
sperm Sperm is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one). Animals produce motile sperm with a tail known as a flagellum, ...
in order to father a child for a third-party female. *
Egg donation Egg donation is the process by which a woman donates eggs to enable another woman to conceive as part of an assisted reproduction treatment or for biomedical research. For assisted reproduction purposes, egg donation typically involves in vitro ...
. A donor provides ova to a woman or couple in order for the egg to be fertilized and implanted in the recipient woman. ** Spindle transfer. A third party's
mitochondrial DNA Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial D ...
is transferred to the future mother's ovum. This is used to prevent
mitochondrial disease Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells. They convert the energy of ...
. *
Embryo donation Embryo donation is one disposition option for users of in vitro fertilisation with remaining fresh or frozen embryos. It is defined as the giving—generally without compensation—of embryos remaining after in vitro fertilization procedures to rec ...
** with
embryo An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male spe ...
s which were originally created for a genetic mother's assisted pregnancy. Once the genetic mother has completed her own treatment, she may donate unused embryos for use by a third party. ** or where embryos are specifically created for donation using donor eggs and donor sperm. *
Embryo adoption Embryo donation is one disposition option for users of in vitro fertilisation with remaining fresh or frozen embryos. It is defined as the giving—generally without compensation—of embryos remaining after in vitro fertilization procedures to rec ...
. Embryos created during a donor's assisted pregnancy are adopted to be implanted in a third party recipient. *
Surrogacy Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman agrees to delivery/labour for another person or people, who will become the child's parent(s) after birth. People may seek a surrogacy arrangement when pregna ...
. An embryo is gestated in a third party's uterus (traditional surrogacy) or a woman is inseminated in order to gestate a child for a third party (straight surrogacy).


Gestation

Gestation is typically initiated by
artificial insemination Artificial insemination is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatment ...
in the case of sperm donation and by
embryo transfer Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy. This technique (which is often used in connection with in vitro fertilizati ...
after
in vitro fertilisation In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...
(IVF) in the case of egg donation, embryo donation, and surrogacy. Thus a child can have a genetic and social (non-genetic, non-biological) father, and a genetic, gestational, and social (non-biological) mother, and any combinations thereof. Theoretically a child thus could have 5 parents.


Donor treatment

A donor treatment is where gametes, i.e. sperm, ova or embryos are provided, or 'donated' by a third party for the purpose of third-party reproduction.


Combinations

Surrogacy Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman agrees to delivery/labour for another person or people, who will become the child's parent(s) after birth. People may seek a surrogacy arrangement when pregna ...
includes, in its wider sense, all situations where a ''surrogate'' carries a pregnancy for another person. Recently, there has been a tendency to separate the gestational carrier situation from the "true" surrogate restricting the term for a woman who provides a combination of ovum donation and gestational carrier services. In a 'conventional surrogacy', a surrogate agrees to be inseminated with the sperm of the male partner of the 'commissioning' couple, or with the sperm of one of the male partners in a same-sex relationship, or with sperm provided by a sperm donor. The surrogate is inseminated, conceives, and hands over the baby at the completion of the pregnancy. In conventional surrogacy, the egg which is fertilized is therefore that of the surrogate. A famous case involving paternity rights and surrogacy is the
Baby M Baby M (born March 27, 1986) was the pseudonym used in the case ''In re Baby M'', 537 A.2d 1227, 109 N.J. 396 (N.J. 1988) for the infant whose legal parentage was in question. Origins ''In re Baby M'' was a custody case that became the first Am ...
case. In a 'gestational surrogacy', a surrogate agrees to the implantation in her of an embryo which may be created either by using an egg provided by another woman who may be part of a 'commissioning' couple, or she may be a single woman. Alternatively, an egg provided by a donor may be used to create the embryo. The embryo implanted in the surrogate may be fertilised using sperm from the male partner of the 'commissioning couple', or by using sperm provided by a sperm donor.
Embryo donation Embryo donation is one disposition option for users of in vitro fertilisation with remaining fresh or frozen embryos. It is defined as the giving—generally without compensation—of embryos remaining after in vitro fertilization procedures to rec ...
is where extra embryos from a successful IVF of a couple are given to other couples or women for transfer with the goal of producing a successful pregnancy. Embryos for
embryo donation Embryo donation is one disposition option for users of in vitro fertilisation with remaining fresh or frozen embryos. It is defined as the giving—generally without compensation—of embryos remaining after in vitro fertilization procedures to rec ...
may also be created specifically for
embryo transfer Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy. This technique (which is often used in connection with in vitro fertilizati ...
using donor eggs and sperm, or in some cases donor eggs and donor sperm. It may thus be seen as a combination of sperm donation and egg donation, since what is donated is a combination of these. Such embryos may also be donated to a 'commissioning' woman or a 'commissioning' couple and gestated by a surrogate where, for example, the 'commissioning' woman or the woman of the 'commissioning' couple is infertile and is unable to bring a pregnancy to full term on medical grounds, or is unwilling for social, medical or other reasons, to do so.


See also

*
Sexual surrogate Sex surrogates, sometimes referred to as surrogate partners, are practitioners trained in addressing issues of intimacy and sexuality. A surrogate partner works in collaboration with a sex therapist to meet the goals of their client. This triadi ...
*
Egg donation Egg donation is the process by which a woman donates eggs to enable another woman to conceive as part of an assisted reproduction treatment or for biomedical research. For assisted reproduction purposes, egg donation typically involves in vitro ...
*
Surrogacy Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman agrees to delivery/labour for another person or people, who will become the child's parent(s) after birth. People may seek a surrogacy arrangement when pregna ...


References


External links


Annotated Bibliography for Children and Parents of Third Party Reproduction
Compiled by the Education Committee, Spring 2007
UK Donorlink
(UK Voluntary Information Exchange and Contact Register for donors and donor-conceived people)

THIRD PARTY REPRODUCTION(Sperm, egg, and embryo donation and surrogacy) A Guide for Patients

Different treatments and methods available for Third Party Reproduction

Various articles on Third Party Reproduction

Third-Party Reproduction, A Comprehensive Guide. Editor. Goldfarb, James M {{Reproductive health Fertility medicine Obstetrics Family Human pregnancy Human reproduction Assisted reproductive technology Assistive technology Medical technology