The tubarial salivary glands, also known as the tubarial glands, are a pair of
salivary gland
The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. Salivary gla ...
s found in
humans
Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, ...
between the
nasal cavity
The nasal cavity is a large, air-filled space above and behind the nose in the middle of the face. The nasal septum divides the cavity into two cavities, also known as fossae. Each cavity is the continuation of one of the two nostrils. The nasal c ...
and
throat
In vertebrate anatomy, the throat is the front part of the neck, internally positioned in front of the vertebrae. It contains the pharynx and larynx. An important section of it is the epiglottis, separating the esophagus from the trachea (windpipe ...
.
Description
The tubarial glands are found in the lateral walls of the
nasopharynx
The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the oesophagus and trachea (the tubes going down to the stomach and the lungs). It is found in vertebrates and invertebrates, though its struct ...
overlying the
torus tubarius
The base of the cartilaginous portion of the Eustachian tube (auditory tube) lies directly under the mucous membrane of the nasal part of the pharynx, where it forms an elevation or cushion, the torus tubarius or torus of the auditory tube, behind ...
.
The tubarial salivary glands bind to
PSMA,
which is how they were discovered.
History
The glands were discovered by a group of Dutch scientists at the
Netherlands Cancer Institute
The Netherlands Cancer Institute (NKI) in Amsterdam was founded in 1913 by, among others, the surgeon Jacob Rotgans.
The NKI, together with the Antoni van Leeuwenhoekziekenhuis, is formed into the NKI-AVL, which combines a scientific research i ...
in September 2020 using
PET/CT scans.
Significance
Most of the significance of the tubarial glands stems from their significance in
radiotherapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radia ...
. It is believed that avoiding the
irradiation
Irradiation is the process by which an object is exposed to radiation. The exposure can originate from various sources, including natural sources. Most frequently the term refers to ionizing radiation, and to a level of radiation that will serve ...
of the glands will prevent many of the side effects of radiotherapy, such as
xerostomia
Xerostomia, also known as dry mouth, is dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause.
This symptom is very common and is often seen as a side ef ...
.
References
Glands
Human throat
2020 in science
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