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A true-breeding organism, sometimes also called a purebred ''(biology slang: pure line'' or ''true-breeding line)'', is an organism that always passes down certain
phenotypic In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...
traits (i.e. physically expressed traits) to its offspring of many generations. An organism is referred to as true breeding for each trait to which this applies, and the term "true-breeding" is also used to describe individual genetic traits. In
Mendelian genetics Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later populari ...
, this means that an organism must be
homozygous Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism. Mo ...
for every trait for which it is considered true breeding; that is, the pairs of
allele An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. ::"The chro ...
s that express a given trait are the same. In a
purebred Purebreds are " cultivated varieties" of an animal species achieved through the process of selective breeding. When the lineage of a purebred animal is recorded, that animal is said to be "pedigreed". Purebreds breed true-to-type which means the ...
strain or breed, the goal is that the organism will "breed true" for the breed-relevant traits. Apomixis and
parthenogenesis Parthenogenesis (; from the Greek grc, παρθένος, translit=parthénos, lit=virgin, label=none + grc, γένεσις, translit=génesis, lit=creation, label=none) is a natural form of asexual reproduction in which growth and developmen ...
, types of asexual reproduction, also result in true breeding, although the organisms are usually not homozygous.


Examples

A purebred variety of cat, such as Siamese, only produces kittens with Siamese characteristics because their ancestors were
inbred Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. By analogy, the term is used in human reproduction, but more commonly refers to the genetic disorders and o ...
until they were homozygous for all of the genes that produce the physical characteristics and temperament associated with the Siamese breed.
Apples An apple is an edible fruit produced by an apple tree (''Malus domestica''). Apple trees are cultivated worldwide and are the most widely grown species in the genus ''Malus''. The tree originated in Central Asia, where its wild ancestor, ' ...
are notorious for not breeding true from seed, which means that they are propagated by grafting. The same is true of many fruit and nut trees. Many commercially produced plants for gardeners are
F1 hybrids An F1 hybrid (also known as filial 1 hybrid) is the first filial generation of offspring of distinctly different parental types. F1 hybrids are used in genetics, and in selective breeding, where the term F1 crossbreed may be used. The term is somet ...
, which if propagated from seed will produce F2 hydrids which are quite different from their parents; the F1 hybrids therefore don't breed true.


See also

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Inbreeding Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. By analogy, the term is used in human reproduction, but more commonly refers to the genetic disorders and o ...
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Homozygous Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") () is the degree to which both copies of a chromosome or gene have the same genetic sequence. In other words, it is the degree of similarity of the alleles in an organism. Mo ...
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Test cross Under the law of dominance in genetics, an individual expressing a dominant phenotype could contain either two copies of the dominant allele (homozygous dominant) or one copy of each dominant and recessive allele (heterozygous dominant). By pe ...
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Purebred Purebreds are " cultivated varieties" of an animal species achieved through the process of selective breeding. When the lineage of a purebred animal is recorded, that animal is said to be "pedigreed". Purebreds breed true-to-type which means the ...


References

{{reflist Classical genetics