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The Trudeau Institute is an independent, not-for-profit, biomedical research center located on a campus in
Saranac Lake, New York Saranac Lake is a village in the state of New York, United States. As of the 2010 census, the population was 5,406, making it the largest community by population in the Adirondack Park. The village is named after Upper, Middle and Lower Saran ...
. Its scientific mission is to make breakthrough discoveries that lead to improved human health. Trudeau scientists work to discover the basic rules governing immunity (the body's natural defense system). The Institute presently employs eight research teams comprising 7 Ph.D.-level scientists, each studying some aspect of immunity. Their studies focus on immune responses to major infectious diseases, such as influenza, sepsis, and tuberculosis, as well as on the role of the immune system in cancer, asthma, allergy, arthritis, colitis, multiple sclerosis and aging. Trudeau researchers use experimental methodologies and mouse models to conduct their research. Shared facilities include animal, flow cytometry, molecular biology, and microscopy cores, as well as biosafety level 2 (BSL-2) and 3 (BSL-3) containment laboratories.


History

The Institute was founded in 1884 as th
Saranac Laboratory for the Study of Tuberculosis
by Dr. Edward Livingston Trudeau as a
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
treatment and research facility. Trudeau had trained as a physician after his elder brother succumbed to tuberculosis. Trudeau himself was diagnosed with tuberculosis in 1873. Following the thinking of the time, his physicians and friends urged a change of climate. He went to live in the
Adirondack Mountains The Adirondack Mountains (; a-də-RÄN-dak) form a massif in northeastern New York with boundaries that correspond roughly to those of Adirondack Park. They cover about 5,000 square miles (13,000 km2). The mountains form a roughly circular ...
, initially at
Paul Smith's Hotel Paul Smith's Hotel, formally known as the Saint Regis House, was founded in 1859 by Apollos (Paul) Smith in the town of Brighton, Franklin County, New York, in what would become the village of Paul Smiths; it was one of the first wilderness r ...
, spending time outdoors, and regained his health. In 1876, he moved to Saranac Lake and established a medical practice. In 1882, Trudeau read about German physician Hermann Brehmer's success treating tuberculosis with a systematic rest cure in cold, clear mountain air. Following this example, Trudeau founded the
Adirondack Cottage Sanitarium The Adirondack Cottage Sanitarium was a tuberculosis sanatorium established in Saranac Lake, New York in 1885 by Dr. Edward Livingston Trudeau. After Trudeau's death in 1915, the institution's name was changed to the Trudeau Sanatorium, followi ...
for the treatment of tuberculosis with the support of several wealthy businessmen. In 1894, after a fire destroyed his small laboratory, Trudeau built the Saranac Laboratory for the Study of Tuberculosis, the first laboratory in the United States dedicated to the study of tuberculosis. He subsequently dedicated his life to pursuing a cure for tuberculosis and was elected the first president of th
National Association for the Study and Prevention of Tuberculosis
the predecessor of th
American Lung Association
He died i
1915
at age 67. Following Trudeau's death, the sanitarium's name was changed to the Trudeau Sanatorium, and a foundation and school were established to train physicians and healthcare professionals in the latest tuberculosis treatment methods. By 1947, more than 15,000 patients had received treatment there. The sanatorium closed in 1954, after the discovery of effective antibiotic treatments for tuberculosis. In 1957 Trudeau's grandson

sold the property to the
American Management Association The American Management Association (AMA) is an American non-profit educational membership organization for the promotion of management, based in New York City. Besides its headquarters there, it has local head offices throughout the world. It o ...
. The proceeds were invested in a new medical research facility built on
Lower Saranac Lake Lower Saranac Lake is one of three connected lakes, part of the Saranac River, near the village of Saranac Lake in the Adirondacks in northern New York. With Middle Saranac Lake and Upper Saranac Lake, a paddle with only one portage is possible. ...
, which became the Trudeau Institute and opened in 1964. Trudeau's Saranac Laboratory has been restored by
Historic Saranac Lake Historic Saranac Lake is a non-profit, membership organization dedicated to the preservation of the history and architectural heritage of the Saranac Lake area of New York State in the Adirondacks. History Founded on 15 January 1980, the organ ...
and now serves as its headquarters and a museum. In July 2020, due to their role in assisting the regional community during the COVID-19 pandemic, the Saranac Lake Chamber of Commerce honored Adirondack Health and the Trudeau Institute as joint partners of the year. The dialogue included a look at what role the Institute plays in global research into pandemic vaccines as the award was presented.


References


External links


Official site
{{authority control Adirondacks Biotechnology organizations Medical research institutes in the United States Saranac Lake, New York Organizations established in 1884 Non-profit organizations based in New York (state) Research institutes in New York (state)