Triple smear, also known as vaginal-cervical-endocervical (VCE) smear is a cytopathology technique for identifying lesions of the female genital tract. The smear is prepared on separate areas of a single slide with three distinct samples, each from

ectocervix The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes during ...

vagina In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...

and

endocervix The cervical canal is the spindle-shaped, flattened canal of the cervix, the neck of the uterus. Anatomy The cervical canal communicates with the uterine cavity via the internal orifice of the uterus (or internal os) and with the vagina via the ...

. Each sample occupies one-third of the glass slide. This method requires expertise as three samples need to be collected rapidly to avoid drying up of the smear. Triple smear is recommended in patients who had a previous abnormal smear (or endometrial debris in previous smear in a climacteric woman), in postmenopausal women, women with perimenopausal bleeding and those with high risk for

endometrial carcinoma Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb). It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. The first sign is most o ...

References

Cytopathology Medical tests Gynaecological cancer {{med-diagnostic-stub