The trigeminovascular system consists of
neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. N ...
s in the
trigeminal nerve
In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and chewin ...
that innervate
cerebral blood vessel
Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Arterie ...
s.
It has been hypothesized that the trigeminovascular system may be involved in some types of
headache
Headache is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of depression in those with severe headaches.
Headaches can occur as a result ...
s.
See also
* Umbellulone
Umbellulone is a headache-inducing monoterpene ketone found in the leaves of the tree ''Umbellularia californica'', sometimes known as the "headache tree".
It is hypothesized to cause headaches by influencing the trigeminovascular system via TRPA ...
References
{{reflist
External links
''Pain: Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery, Second Edition'' by Rajesh Munglani, William K. Schmidt and Chas Bountra, page 321
''Functional MRI'' by Chrit T. W. Moonen, P. A. Bandettini, page 21
''Craniofacial dysfunction and pain: manual therapy, assessment and management'' by Harry Von Piekartz, Lynn Bryden, page 90
Trigeminal nerve