Tricin Synthase
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Tricin synthase (, ''ROMT-17'', ''ROMT-15'', ''HvOMT1'', ''ZmOMT1'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
''S-adenosyl-L-methionine:tricetin 3',5'-O-dimethyltransferase''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: 2
S-adenosyl-L-methionine ''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throug ...
+
tricetin Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as ''Eucalyptus globulus''. This compound shows anticancer effects on human breast adenocarcinoma ...
\rightleftharpoons 2 S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin (overall reaction) :(1a) S-adenosyl-L-methionine + tricetin \rightleftharpoons S-adenosyl-L-homocysteine + 3'-O-methyltricetin :(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin \rightleftharpoons S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin The enzymes from ''
Oryza sativa ''Oryza sativa'', commonly known as Asian rice or indica rice, is the plant species most commonly referred to in English as ''rice''. It is the type of farmed rice whose cultivars are most common globally, and was first domesticated in the Yan ...
'' (ROMT-15 and ROMT-17) catalyses the stepwise
methylation In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These t ...
of tricetin to its 3'-mono- and 3',5'-dimethyl ethers.


References


External links

* {{Portal bar, Biology, border=no EC 2.1.1 Flavones metabolism