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Trichilemmoma (also known as "tricholemmoma"Busam Klaus J., ''Dermatopathology'' s.386; 2010 Saunders ) is a
benign
Malignancy () is the tendency of a medical condition to become progressively worse.
Malignancy is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous benign tumor, ''benign'' tumor in that a malign ...
cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other animal coverings, such as the arthropod exoskeleton, have different de ...
neoplasm
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
that shows differentiation toward cells of the outer root sheath The outer root sheath or external root sheath of the hair follicle encloses the inner root sheath and hair shaft.James, William; Berger, Timothy; Elston, Dirk (2005) ''Andrews' Diseases of the Skin: Clinical Dermatology'' (10th ed.). Saunders. Page ...
. The lesion is often seen in the face and neck region. Multifocal occurrence is associated with Cowden syndrome
Cowden syndrome (also known as Cowden's disease and multiple hamartoma syndrome) is an autosomal dominant inherited condition characterized by benign overgrowths called hamartomas as well as an increased lifetime risk of breast, thyroid, uterine, ...
, in which hamartomatous intestinal polyposis
A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended fr ...
is seen in conjunction with multiple tricholemmoma lesions.Additional images
See also
*Cowden syndrome
Cowden syndrome (also known as Cowden's disease and multiple hamartoma syndrome) is an autosomal dominant inherited condition characterized by benign overgrowths called hamartomas as well as an increased lifetime risk of breast, thyroid, uterine, ...
* Trichilemmal carcinoma
Trichilemmal carcinoma is a cutaneous condition reported to arise on sun-exposed areas, most commonly the face and ears.
See also
* Trichilemmoma
* Skin lesion
A skin condition, also known as cutaneous condition, is any medical condition t ...
* List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
* List of cutaneous neoplasms associated with systemic syndromes
Many cutaneous neoplasms occur in the setting of systemic syndromes.
See also
*List of cutaneous conditions
*List of contact allergens
*List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer
*List of cutaneous ...
References
External links
Epidermal nevi, neoplasms, and cysts {{Epidermal-growth-stub