Tricetin 3',4',5'-O-trimethyltransferase (, ''FOMT'', ''TaOMT1'', ''TaCOMT1'', ''TaOMT2'') is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

with systematic name ''S-adenosyl-L-methionine:tricetin 3',4',5'-O-trimethyltransferase''. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

: 3 S-adenosyl-L-methionine +

tricetin Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as ''Eucalyptus globulus''. This compound shows anticancer effects on human breast adenocarcinoma ...

\rightleftharpoons

3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin (overall reaction) :(1a) S-adenosyl-L-methionine + tricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3'-O-methyltricetin :(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin :(1c) S-adenosyl-L-methionine + 3',5'-O-dimethyltricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin The enzyme from ''

Triticum aestivum Common wheat (''Triticum aestivum''), also known as bread wheat, is a cultivated wheat species. About 95% of wheat produced worldwide is common wheat; it is the most widely grown of all crops and the cereal with the highest monetary yield. Ta ...

'' catalyses the sequential O-methylation of

via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin.

References

External links

* {{Portal bar, Biology, border=no EC 2.1.1 O-methylated flavones metabolism