Transient neonatal diabetes mellitus (TNDM) is a form of
neonatal diabetes
Neonatal diabetes mellitus (NDM) is a disease that affects an infant and their body's ability to produce or use insulin. NDM is a monogenic (controlled by a single gene) form of diabetes that occurs in the first 6 months of life. Infants do not pr ...
presenting at birth that is not permanent. This disease is considered to be a type of
maturity onset diabetes of the young (MODY).
Types
Cause
This condition has to do with genetics and is often associated with having an added Chromosome 7 gene (mostly from the paternal side).
The form on chromosome 6 can involve
imprinting.
Diagnosis
Management
See also
*
Permanent neonatal diabetes mellitus
Permanent neonatal diabetes mellitus (PNDM) is a newly identified and potentially treatable form of monogenic diabetes. This type of neonatal diabetes is caused by activating mutations of the ''KCNJ11'' gene, which codes for the Kir6.2 subunit of t ...
References
Further reading
GeneReview/NIH/UW entry on 6q24-Related Transient Neonatal Diabetes Mellitush1>
External links
Diabetes
Neonatology
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